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Results for “Locally Advanced Unresectable or Metastatic Solid Tumor”

136 trials

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Showing 20 of 136 results

Testing effectiveness (Phase 2)Looking for participantsNCT05592626
What this trial is testing

A Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsGenital Neoplasm, FemaleUrogenital Neoplasms+11 more
Marengo Therapeutics, Inc. 366
Not applicableAvailableNCT06948955
What this trial is testing

Expanded Access to Bezuclastinib to be Coadministered With Sunitinib for Patients With Gastrointestinal Stromal Tumors

Who this might be right for
Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors
Cogent Biosciences, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT07105215
What this trial is testing

A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC278 in the Treatment of Solid Tumors

Who this might be right for
Solid Tumors
RemeGen Co., Ltd. 312
Testing effectiveness (Phase 2)Looking for participantsNCT07359820
What this trial is testing

Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

Who this might be right for
FGFR2 Gene Fusion/RearrangementOther Solid Tumors, Adult
Elevar Therapeutics 30
Early research (Phase 1)Active Not RecruitingNCT07131189
What this trial is testing

FL115 Monotherapy in Unresectable or Metastatic Solid Tumors

Who this might be right for
Locally Advanced/Metastatic Solid Tumors
Suzhou Forlong Biotechnology Co., Ltd 30
Testing effectiveness (Phase 2)Ended earlyNCT04800627
What this trial is testing

Pevonedistat and Pembrolizumab for the Treatment of dMMR/MSI-H Metastatic or Locally Advanced Unresectable Solid Tumor

Who this might be right for
Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
M.D. Anderson Cancer Center 2
Testing effectiveness (Phase 2)UnknownNCT05842785
What this trial is testing

TSN222 in Subjects With Advanced Solid Tumors or Lymphomas

Who this might be right for
Has a Pathologically Documented Unresectable Locally Advanced or Metastatic Solid Tumor or Lymphoma
Tyligand Bioscience (Shanghai) Limited 162
Testing effectiveness (Phase 2)Study completedNCT02401815
What this trial is testing

CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors

Who this might be right for
Gastrointestinal Stromal Tumors
Cogent Biosciences, Inc. 51
Early research (Phase 1)Ended earlyNCT06364696
What this trial is testing

Find a Suitable Dose of ASP4396 in Adults With Solid Tumors

Who this might be right for
Solid Tumor
Astellas Pharma Inc 60
Testing effectiveness (Phase 2)Ended earlyNCT00130936
What this trial is testing

Study of Epirubicin (Pharmorubicin®), Carboplatin (Paraplatin®) and Capecitabine (Xeloda®) (ECC) in the Treatment of Unresectable Locally Advanced or Metastatic Gastric/Gastroesophageal Junction Cancer With Pharmacogenetic Correlates

Who this might be right for
Gastric CancerEsophageal CancerTumors
AHS Cancer Control Alberta 50
Early research (Phase 1)Active Not RecruitingNCT05311397
What this trial is testing

A166 in Patients With Advanced Solid Malignant Tumors

Who this might be right for
Breast Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 120
Testing effectiveness (Phase 2)Active Not RecruitingNCT06003231
What this trial is testing

Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2

Who this might be right for
Carcinoma, Non-Small-Cell LungOvarian NeoplasmsEndometrial Neoplasms+1 more
Seagen, a wholly owned subsidiary of Pfizer 120
Testing effectiveness (Phase 2)UnknownNCT04215159
What this trial is testing

Trastuzumab Biosimilar (Samfenet®) Plus Treatment of Physician's Choice (TPC) in Patients With HER2-positive Solid Tumor

Who this might be right for
HER-2 Protein OverexpressionHER-2 Gene Amplification
Jin-Hee Ahn 42
Testing effectiveness (Phase 2)Ended earlyNCT04032704
What this trial is testing

Ladiratuzumab Vedotin in Advanced Solid Tumors

Who this might be right for
Small Cell Lung CancerNon-small Cell Lung Cancer, SquamousNon-small Cell Lung Cancer, Non-squamous+6 more
Seagen Inc. 205
Testing effectiveness (Phase 2)Ended earlyNCT05220098
What this trial is testing

First-in-Human Study of TAK-280 in Participants With Solid Tumors

Who this might be right for
Unresectable Locally Advanced or Metastatic Cancer
Takeda 69
Early research (Phase 1)Active Not RecruitingNCT05653869
What this trial is testing

APS03118 in Advanced Solid Tumors Harboring RET Mutations or Fusions

Who this might be right for
RET-altered Solid Tumors
Applied Pharmaceutical Science, Inc. 108
Testing effectiveness (Phase 2)Looking for participantsNCT05205850
What this trial is testing

RC118 in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Who this might be right for
Advanced Solid Tumor
RemeGen Co., Ltd. 135
Large-scale testing (Phase 3)Study completedNCT04799249
What this trial is testing

Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Gemcitabine and Carboplatin for Metastatic Triple-Negative Breast Cancer (TNBC)

Who this might be right for
TNBC - Triple-Negative Breast CancerBreast Cancer
G1 Therapeutics, Inc. 194
Testing effectiveness (Phase 2)Looking for participantsNCT07287995
What this trial is testing

ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 428
Early research (Phase 1)Looking for participantsNCT07524322
What this trial is testing

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

Who this might be right for
Breast CancerOvarian CancerEndometrial Cancer+6 more
Regor Pharmaceuticals Inc. 63
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