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Results for “Locally Advanced Urothelial Cancer”

208 trials

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Showing 20 of 208 results

Early research (Phase 1)WithdrawnNCT07217496
What this trial is testing

N-803 in Combination With Pembrolizumab and Enfortumab Vedotin for Treatment of Urothelial Cancer

Who this might be right for
Metastatic Urothelial CarcinomaUrothelial CarcinomaLocally Advanced Urothelial Carcinoma+1 more
Vadim S Koshkin
Testing effectiveness (Phase 2)Active Not RecruitingNCT05923190
What this trial is testing

Enfortumab Vedotin Schedule De-escalation in Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial CarcinomaMetastatic Urothelial CarcinomaLocally Advanced Urothelial Carcinoma
Fox Chase Cancer Center 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04953104
What this trial is testing

ARID1A and/or KDM6A Mutation and CXCL13 Expression

Who this might be right for
Locally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis Urothelial CarcinomaLocally Advanced Ureter Urothelial Carcinoma+29 more
M.D. Anderson Cancer Center 6
Early research (Phase 1)Looking for participantsNCT05614739
What this trial is testing

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Who this might be right for
Urinary Bladder NeoplasmsNeoplasm MetastasisUreteral Neoplasms
Eli Lilly and Company 535
Not applicableStudy completedNCT05366725
What this trial is testing

Learn About the Study Medicine (Called Avelumab) in People With Advanced Urothelial Cancer After Chemotherapy

Who this might be right for
Urothelial Cancer
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 106
Large-scale testing (Phase 3)Not Yet RecruitingNCT07526792
What this trial is testing

SYS6002 vs Chemotherapy in Patients With Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
CSPC Megalith Biopharmaceutical Co.,Ltd. 406
Large-scale testing (Phase 3)Active Not RecruitingNCT03967977
What this trial is testing

Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
BeiGene 420
Testing effectiveness (Phase 2)Looking for participantsNCT07287995
What this trial is testing

ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 428
Testing effectiveness (Phase 2)Active Not RecruitingNCT04579380
What this trial is testing

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Who this might be right for
Uterine NeoplasmsUterine Cervical NeoplasmsBiliary Tract Neoplasms+3 more
Seagen, a wholly owned subsidiary of Pfizer 217
Early research (Phase 1)Enrolling By InvitationNCT07218003
What this trial is testing

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

Who this might be right for
Non Small Cell Lung CancerCervical CancerHead and Neck Squamous Cell Cancer+7 more
Rondo Therapeutics 149
Large-scale testing (Phase 3)Active Not RecruitingNCT04223856
What this trial is testing

Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

Who this might be right for
Urothelial Cancer
Astellas Pharma Global Development, Inc. 886
Testing effectiveness (Phase 2)UnknownNCT04264936
What this trial is testing

RC48-ADC(Antibody Drug Conjugate) and JS001 to Evaluate the Safety and Pharmacokinetics of Subjects With Locally Advanced or Metastatic Urothelial Cancer

Who this might be right for
Urothelial Carcinoma
Peking University Cancer Hospital & Institute 36
Testing effectiveness (Phase 2)Study completedNCT03679767
What this trial is testing

INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203)

Who this might be right for
Metastatic Non-small Cell Lung CancerLocally Advanced Urothelial CancerMetastatic Urothelial Cancer+4 more
Incyte Corporation 121
Testing effectiveness (Phase 2)Study completedNCT01023958
What this trial is testing

Intravenous BI 6727 (Volasertib) in 2nd Line Treatment of Urothelial Cancer

Who this might be right for
Neoplasms
Boehringer Ingelheim 50
Large-scale testing (Phase 3)Study completedNCT03898180
What this trial is testing

Study of First-line Pembrolizumab (MK-3475) With Lenvatinib (MK-7902/E7080) in Urothelial Carcinoma Cisplatin-ineligible Participants Whose Tumors Express Programmed Cell Death-Ligand 1 and in Participants Ineligible for Platinum-containing Chemotherapy (MK-7902-011/E7080-G000-317/ LEAP-011)

Who this might be right for
Urothelial Carcinoma
Merck Sharp & Dohme LLC 505
Early research (Phase 1)Active Not RecruitingNCT05867303
What this trial is testing

A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
MelanomaUrothelial CarcinomaRenal Cell Carcinoma+3 more
RemeGen Co., Ltd. 48
Testing effectiveness (Phase 2)WithdrawnNCT05107427
What this trial is testing

Study of MRx0518 and Avelumab in Patients With Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
4D pharma plc
Testing effectiveness (Phase 2)Looking for participantsNCT07043972
What this trial is testing

Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Fox Chase Cancer Center 55
Early research (Phase 1)Looking for participantsNCT07492628
What this trial is testing

Dual-Target Nectin-4/HER2 CAR-NK Cells in Advanced Urothelial Carcinoma

Who this might be right for
Bladder CancerUrothelial CarcinomaMetastatic Urothelial Carcinoma+2 more
Beijing Biotech 42
Testing effectiveness (Phase 2)Looking for participantsNCT06405425
What this trial is testing

BL-B01D1 + PD-1 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Sichuan Baili Pharmaceutical Co., Ltd. 52
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