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Results for “Locally Advanced Urothelial Carcinoma”

211 trials

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Showing 20 of 211 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03854474
What this trial is testing

Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma

Who this might be right for
Locally Advanced Urothelial CarcinomaMetastatic Urothelial CarcinomaStage III Bladder Cancer AJCC v8+1 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Study completedNCT03421652
What this trial is testing

Nivolumab and RT in Treating Patients With Localized/Locally Advanced Urothelial Bladder Cancer Ineligible for Chemo

Who this might be right for
Stage II Bladder Urothelial Carcinoma AJCC v6 and v7Stage III Bladder Urothelial Carcinoma AJCC v6 and v7Stage IV Bladder Urothelial Carcinoma AJCC v7
Barbara Ann Karmanos Cancer Institute 20
Large-scale testing (Phase 3)Looking for participantsNCT06738251
What this trial is testing

A Phase III Study of SHR-A2102 Versus Investigator-selected Therapy in Advanced Urothelial Carcinoma

Who this might be right for
Advanced Urothelial Carcinoma
Shanghai Hengrui Pharmaceutical Co., Ltd. 402
Not applicableNot Yet RecruitingNCT06798246
What this trial is testing

HEFTME System for Adjuvant Therapeutic Selection of Locally Advanced UTUC Postoperatively：A Perspective Cohort Study

Who this might be right for
Upper Tract Urothelial Carcinoma
Peking University First Hospital 200
Testing effectiveness (Phase 2)Study completedNCT01090466
What this trial is testing

Gemcitabine Hydrochloride, Cisplatin, and Temsirolimus as First-Line Therapy in Treating Patients With Locally Advanced and/or Metastatic Transitional Cell Cancer of the Urothelium

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and UreterUrethral Cancer
Cardiff University 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT04152499
What this trial is testing

Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)

Who this might be right for
Epithelial Ovarian CancerGastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma+7 more
Klus Pharma Inc. 1,410
Testing effectiveness (Phase 2)Looking for participantsNCT07043972
What this trial is testing

Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Fox Chase Cancer Center 55
Early research (Phase 1)Ended earlyNCT03915405
What this trial is testing

KHK2455 (IDO Inhibitor) Plus Avelumab in Adult Subjects With Advanced Bladder Cancer

Who this might be right for
Urothelial Carcinoma
Kyowa Kirin, Inc. 16
Testing effectiveness (Phase 2)UnknownNCT04211012
What this trial is testing

A Study on Toripalimab Plus Nab-Paclitaxel With or Without Cisplatin as First-line Treatment of Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Jun Guo 30
Large-scale testing (Phase 3)Study completedNCT00033436
What this trial is testing

Radiation Therapy With or Without Carbogen and Niacinamide in Treating Patients With Bladder Cancer

Who this might be right for
Bladder Cancer
Mount Vernon Cancer Centre at Mount Vernon Hospital 330
Testing effectiveness (Phase 2)Study completedNCT02236195
What this trial is testing

Study of Mocetinostat in Patients With Urothelial Carcinoma Having Inactivating Alterations of Specific Genes

Who this might be right for
Urothelial Carcinoma
Mirati Therapeutics Inc. 17
Large-scale testing (Phase 3)Study completedNCT02928406
What this trial is testing

Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract

Who this might be right for
Urinary Tract Cancer
Hoffmann-La Roche 1,004
Testing effectiveness (Phase 2)Active Not RecruitingNCT05544552
What this trial is testing

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations

Who this might be right for
Locally Advanced Urothelial CarcinomaMetastatic Urothelial CarcinomaSolid Tumor+11 more
Tyra Biosciences, Inc 310
Testing effectiveness (Phase 2)Study completedNCT00077688
What this trial is testing

TOCOSOL(TM) Paclitaxel in Metastatic or Locally Advanced Unresectable Transitional Cell Carcinoma of the Urothelium

Who this might be right for
Bladder NeoplasmsUreteral NeoplasmsUrethral Neoplasms+1 more
Achieve Life Sciences 44
Testing effectiveness (Phase 2)Study completedNCT00526656
What this trial is testing

Sunitinib in Treating Patients With Locally Advanced Bladder Cancer

Who this might be right for
Bladder Cancer
Case Comprehensive Cancer Center 9
Testing effectiveness (Phase 2)UnknownNCT05318339
What this trial is testing

Trastuzumab and Pyrotinib in HER2 Positive Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Carcinoma, Transitional CellHER-2 Gene Amplification
Chinese Academy of Medical Sciences 30
Testing effectiveness (Phase 2)Study completedNCT00714025
What this trial is testing

A Single Arm, Multicenter, Phase II Trial of RAD001 as Monotherapy in the Palliative Treatment of Patients With TCC After Failure of Chemotherapy

Who this might be right for
Transitional Cell Carcinoma
Cliniques universitaires Saint-Luc- Université Catholique de Louvain 40
Early research (Phase 1)Study completedNCT02573259
What this trial is testing

A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors

Who this might be right for
Part 1MELANOMASCCHN+6 more
Pfizer 147
Testing effectiveness (Phase 2)Ended earlyNCT03324282
What this trial is testing

First-line Gemcitabine/Cisplatin +/- Avelumab in Locally Advanced or Metastatic Bladder Carcinoma

Who this might be right for
Bladder Carcinoma
University Hospital, Bordeaux 65
Testing effectiveness (Phase 2)Looking for participantsNCT05923190
What this trial is testing

Enfortumab Vedotin Schedule De-escalation in Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial CarcinomaMetastatic Urothelial CarcinomaLocally Advanced Urothelial Carcinoma
Fox Chase Cancer Center 70
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