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Results for “Locally Advanced Urothelial Carcinoma”

224 trials

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Showing 20 of 224 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03093922
What this trial is testing

Two Dosing Schedules of Atezolizumab in Combination With Gemcitabine and Cisplatin as First-Line Treatment for Metastatic Bladder Cancer

Who this might be right for
Urothelial CarcinomaLocally AdvancedUnresectable
Memorial Sloan Kettering Cancer Center 32
Large-scale testing (Phase 3)Study completedNCT03410693
What this trial is testing

Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Carcinoma, Transitional Cell
Bayer 175
Testing effectiveness (Phase 2)Active Not RecruitingNCT06483334
What this trial is testing

Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab in Advanced Urothelial Carcinoma (MK-3475-04C/KEYMAKER-U04)

Who this might be right for
Metastatic Urothelial CarcinomaLocally Advanced Urothelial Carcinoma
Merck Sharp & Dohme LLC 38
Testing effectiveness (Phase 2)UnknownNCT03676946
What this trial is testing

A Clinical Study of PD-L1 Antibody ZKAB001（Drug Code） in Locally Advanced and Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Lee's Pharmaceutical Limited 15
Testing effectiveness (Phase 2)Looking for participantsNCT05600127
What this trial is testing

Chemotherapy and Sequential Immunotherapy for Locally Advanced Urothelial Cancer

Who this might be right for
Urothelial Carcinoma
Erasmus Medical Center 64
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more
Mayo Clinic 138
Testing effectiveness (Phase 2)Ended earlyNCT03029832
What this trial is testing

MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-Based Therapy

Who this might be right for
Urothelial Carcinoma
Genentech, Inc. 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Looking for participantsNCT07034053
What this trial is testing

Clofarabine Therapy in Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Advanced Urothelial CarcinomaMetastatic Urothelial Cancer
Ekaterina Laukhtina 50
Not applicableStudy completedNCT05902494
What this trial is testing

HER2 and LA/mUC: A Multi-country Chart Review Cohort Study

Who this might be right for
Urothelial Carcinoma
Seagen, a wholly owned subsidiary of Pfizer 389
Not applicableNot Yet RecruitingNCT06798246
What this trial is testing

HEFTME System for Adjuvant Therapeutic Selection of Locally Advanced UTUC Postoperatively：A Perspective Cohort Study

Who this might be right for
Upper Tract Urothelial Carcinoma
Peking University First Hospital 200
Not applicableApproved For MarketingNCT04136808
What this trial is testing

An Expanded Access Treatment Protocol of Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Locally Advanced or Metastatic Urothelial Carcinoma (UC)
Astellas Pharma Global Development, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT05267626
What this trial is testing

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
Advanced Solid TumorMetastatic CancerCutaneous Melanoma+1 more
Aulos Bioscience, Inc. 159
Testing effectiveness (Phase 2)Active Not RecruitingNCT03601455
What this trial is testing

Radiation Therapy and Durvalumab With or Without Tremelimumab in Treating Participants With Unresectable, Locally Advanced, or Metastatic Bladder Cancer

Who this might be right for
Bladder Urothelial CarcinomaStage IV Bladder Cancer AJCC v8Stage IVA Bladder Cancer AJCC v8+1 more
Jonsson Comprehensive Cancer Center 13
Testing effectiveness (Phase 2)Ended earlyNCT01374789
What this trial is testing

PURO Panitumumab in Combination With Gemcitabine/Cisplatin in Advanced Urothelial Cancer

Who this might be right for
Urinary Bladder Cancer
WiSP Wissenschaftlicher Service Pharma GmbH 2
Testing effectiveness (Phase 2)Ended earlyNCT04047693
What this trial is testing

Neoadjuvant Dose Dense MVAC in MIBC and Locally Advanced Urothelial Carcinoma

Who this might be right for
Muscle Invasive Bladder CancerUrothelial CarcinomaNeoadjuvant Chemotherapy
Pusan National University Yangsan Hospital 24
Large-scale testing (Phase 3)Not Yet RecruitingNCT07526792
What this trial is testing

SYS6002 vs Chemotherapy in Patients With Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
CSPC Megalith Biopharmaceutical Co.,Ltd. 406
Testing effectiveness (Phase 2)Study completedNCT00003175
What this trial is testing

Fluorouracil in Treating Patients With Recurrent or Metastatic Bladder Cancer

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and UreterUrethral Cancer
Medical Research Council 45
Testing effectiveness (Phase 2)Looking for participantsNCT05732831
What this trial is testing

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Tango Therapeutics, Inc. 225
Testing effectiveness (Phase 2)Ended earlyNCT05714553
What this trial is testing

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Who this might be right for
Advanced CancerAdvanced Solid TumorNeoplasm Malignant+14 more
NuCana plc 19
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