Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Locally Advanced and Metastatic Solid Tumors”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT04770688
What this trial is testing

Advanced Lung Tumor Treated by Osimertinib Plus Anlotinib

Who this might be right for
Non-Small Cell Lung Cancer With EGFR MutationLocally Advanced Solid TumorMetastatic Cancer+1 more
Shanghai Chest Hospital 25
Early research (Phase 1)Study completedNCT03238027
What this trial is testing

Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

Who this might be right for
Solid TumorMetastatic TumorLocally Advanced Malignant Neoplasm+1 more
Syndax Pharmaceuticals 45
Testing effectiveness (Phase 2)Looking for participantsNCT03093116
What this trial is testing

Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

Who this might be right for
Locally Advanced Solid TumorsMetastatic Solid Tumors
Turning Point Therapeutics, Inc. 500
Early research (Phase 1)Looking for participantsNCT05857332
What this trial is testing

SG1906 for CLDN18.2-Positive Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Hangzhou Sumgen Biotech Co., Ltd. 60
Early research (Phase 1)Looking for participantsNCT06493864
What this trial is testing

BL-B16D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors

Who this might be right for
Breast CancerSolid Tumor
Sichuan Baili Pharmaceutical Co., Ltd. 21
Testing effectiveness (Phase 2)Looking for participantsNCT07227298
What this trial is testing

Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

Who this might be right for
Advanced/Metastatic Non-Small Cell Lung CancerCarcinoma, Non-Small Cell LungNon-Small Cell Lung Cancer
Pfizer 162
Early research (Phase 1)Ended earlyNCT02110563
What this trial is testing

Phase I, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Solid Tumors, Multiple Myeloma, or Lymphoma

Who this might be right for
Solid TumorsMultiple MyelomaNon-Hodgkins Lymphoma+3 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 50
Early research (Phase 1)Study completedNCT01449370
What this trial is testing

Dose Escalation Study of TAK-117 (MLN1117) in Subjects With Advanced Cancer

Who this might be right for
Metastatic Solid Tumors
Millennium Pharmaceuticals, Inc. 125
Testing effectiveness (Phase 2)UnknownNCT05102214
What this trial is testing

HLX301 (TIGIT×PDL1 Bispecific) in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid TumorsNon-small Cell Lung Cancer
Shanghai Henlius Biotech 150
Early research (Phase 1)Looking for participantsNCT07094204
What this trial is testing

Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Who this might be right for
Solid TumorNon-Small-Cell Lung CancerPancreatic Ductal Adenocarcinoma+1 more
Astellas Pharma Inc 364
Early research (Phase 1)Looking for participantsNCT07284186
What this trial is testing

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Esophageal Squamous Cell CarcinomaGastric AdenocarcinomaGastric Squamous Cell Carcinoma+7 more
Plexium, Inc. 155
Early research (Phase 1)Study completedNCT01976741
What this trial is testing

Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)

Who this might be right for
Neoplasms
Bayer 168
Early research (Phase 1)Study completedNCT00095914
What this trial is testing

Paclitaxel and ABI-007 in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
National Institutes of Health Clinical Center (CC)
Testing effectiveness (Phase 2)Looking for participantsNCT07213830
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

Who this might be right for
Advanced Solid TumorMetastatic Solid Tumor
Ipsen 102
Early research (Phase 1)Study completedNCT03027128
What this trial is testing

QUILT-3.028: Study of haNK™ for Infusion in Subjects With Metastatic or Locally Advanced Solid Tumors

Who this might be right for
Solid Tumor
ImmunityBio, Inc. 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT02568267
What this trial is testing

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)

Who this might be right for
Breast CancerCholangiocarcinomaColorectal Cancer+13 more
Hoffmann-La Roche 534
Testing effectiveness (Phase 2)UnknownNCT05086666
What this trial is testing

A Phase 1b/2 Clinical Study to Evaluate the Safety and Tolerability and Efficacy of AZD4547

Who this might be right for
Urothelial Carcinoma
Abbisko Therapeutics Co, Ltd 108
Early research (Phase 1)Looking for participantsNCT04777994
What this trial is testing

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

Who this might be right for
Advanced Solid Tumor Cancer
Calico Life Sciences LLC 248
Testing effectiveness (Phase 2)Study completedNCT02983045
What this trial is testing

A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors

Who this might be right for
MelanomaRenal Cell CarcinomaNon Small Cell Lung Cancer+4 more
Nektar Therapeutics 557
Early research (Phase 1)UnknownNCT03284502
What this trial is testing

HM95573 in Combination With Either Cobimetinib or Cetuximab in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Solid TumorMetastatic Solid Tumor
Hanmi Pharmaceutical Company Limited 148
Next Page