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Results for “Locally Advanced or Metastatic CRC”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03485209
What this trial is testing

Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors

Who this might be right for
Colorectal NeoplasmsCarcinoma, Non-Small-Cell LungExocrine Pancreatic Cancer+1 more
Seagen, a wholly owned subsidiary of Pfizer 350
Post-approval studies (Phase 4)Not Yet RecruitingNCT07446465
What this trial is testing

FOLFOX Chemotherapy Combined With Fruquintinib and Serplulimab as First-Line Conversion Therapy for Initially Unresectable pMMR/MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer (Locally Advanced or Metastatic)Colorectal Cancer Microsatellite Stable (MSS)
Ye Xu 42
Testing effectiveness (Phase 2)Study completedNCT00026299
What this trial is testing

Oxaliplatin With or Without Gefitinib in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
University of Chicago 14
Testing effectiveness (Phase 2)Looking for participantsNCT06682793
What this trial is testing

Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNon-Small Cell Lung+14 more
A2 Biotherapeutics Inc. 240
Early research (Phase 1)Study completedNCT03821233
What this trial is testing

A Dose Finding Study of ZW49 in Patients With HER2-Positive Cancers

Who this might be right for
HER2-expressing Cancers
Zymeworks BC Inc. 112
Early research (Phase 1)Study completedNCT02457793
What this trial is testing

The Safety, Tolerability, and Effects of Cobimetinib and GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer, Metastatic Colorectal Cancer, Metastatic Non Small Cell Lung Cancer, Metastatic Cancers, Melanoma
Genentech, Inc. 24
Early research (Phase 1)Ended earlyNCT06364696
What this trial is testing

Find a Suitable Dose of ASP4396 in Adults With Solid Tumors

Who this might be right for
Solid Tumor
Astellas Pharma Inc 60
Testing effectiveness (Phase 2)Looking for participantsNCT06008054
What this trial is testing

SI-B003, BL-B01D1+SI-B003 and BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Esophageal Cancer, Gastric Cancer, Colorectal Cancer and Other Gastrointestinal Tumors

Who this might be right for
Esophageal CancerGastric CancerColorectal Cancer
Sichuan Baili Pharmaceutical Co., Ltd. 376
Early research (Phase 1)Ended earlyNCT06625515
What this trial is testing

First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers

Who this might be right for
Advanced Solid TumorsBreast Cancer RecurrentColorectal Cancer Metastatic+3 more
Accent Therapeutics 17
Not applicableStudy completedNCT01811108
What this trial is testing

Assessment of Clinical Practice Administration of Chemotherapy and Anti-angiogenic Agent (Bevacizumab) in Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Hellenic Oncology Research Group 670
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07260058
What this trial is testing

Immune Cell Therapy for Advanced Solid Tumors

Who this might be right for
Lung Cancer (Locally Advanced or Metastatic)Liver Cancer (Locally Advanced or Metastatic)Colorectal Cancer (Locally Advanced or Metastatic)+2 more
Liaoning Medical Diagnosis and Treatment Technology Research and Development Co., Ltd. 48
Testing effectiveness (Phase 2)Looking for participantsNCT06051695
What this trial is testing

Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNSCLC+17 more
A2 Biotherapeutics Inc. 474
Testing effectiveness (Phase 2)Study completedNCT00094809
What this trial is testing

Chemotherapy Administered Every 2 Weeks With or Without Pegfilgrastim in Subjects With Advanced or Metastatic Colon Cancer

Who this might be right for
Colon CancerColorectal CancerRectal Cancer
Amgen 252
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07752875
What this trial is testing

LG00313112 in Participants With Advanced Solid Malignancies Harboring a TP53 Y220C Mutation

Who this might be right for
Ovarian CancerSmall Cell Lung CancerNon Small Cell Lung Cancer+7 more
LG Chem 250
Not applicableStudy completedNCT00040820
What this trial is testing

Oxaliplatin in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Roswell Park Cancer Institute
Testing effectiveness (Phase 2)Ended earlyNCT03435640
What this trial is testing

REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies

Who this might be right for
MelanomaMerkel Cell CarcinomaTriple Negative Breast Cancer+4 more
Nektar Therapeutics 64
Early research (Phase 1)Study completedNCT01390818
What this trial is testing

Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Solid TumorMetastatic Solid TumorBreast Cancer+3 more
EMD Serono 146
Early research (Phase 1)Active Not RecruitingNCT05581004
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid TumorsNSCLCHNSCC+9 more
Genentech, Inc. 165
Testing effectiveness (Phase 2)Looking for participantsNCT07693751
What this trial is testing

Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer (Locally Advanced or Metastatic)
SOTIO Biotech a.s. 100
Testing effectiveness (Phase 2)Study completedNCT02460198
What this trial is testing

Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Previously-Treated Locally Advanced Unresectable or Metastatic Colorectal Cancer (MK-3475-164/KEYNOTE-164)

Who this might be right for
Colorectal Carcinoma
Merck Sharp & Dohme LLC 124
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