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Results for “Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma”

66 trials

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Showing 20 of 66 results

Early research (Phase 1)Ended earlyNCT03809624
What this trial is testing

Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer

Who this might be right for
Metastatic Solid TumorsNon-small Cell Lung CancerMelanoma+6 more
Inhibrx Biosciences, Inc 160
Testing effectiveness (Phase 2)UnknownNCT05522894
What this trial is testing

AK104 Alone or in Combination With Chemotherapy in the First-line Treatment of ESCC

Who this might be right for
Unresectable Esophageal Squamous Cell CarcinomaLocally Advanced Esophageal Squamous Cell CarcinomaMetastatic Esophageal Squamous Cell Carcinoma
Chinese Academy of Medical Sciences 80
Testing effectiveness (Phase 2)UnknownNCT05990231
What this trial is testing

Cadonilimab/Anlotinib in Locally Advanced or Relapsed/Metastatic ESCC Patients After Failure of PD-1 Combined With Platinum-containing Chemotherapy

Who this might be right for
Esophageal Squamous Cell Carcinoma
Second Affiliated Hospital, Zhejiang University, School of Medicine 35
Testing effectiveness (Phase 2)Looking for participantsNCT05592626
What this trial is testing

A Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsGenital Neoplasm, FemaleUrogenital Neoplasms+11 more
Marengo Therapeutics, Inc. 366
Testing effectiveness (Phase 2)Study completedNCT00003055
What this trial is testing

Cisplatin and Irinotecan in Treating Patients With Locally Advanced or Metastatic Esophageal or Gastric Cancer

Who this might be right for
Esophageal CancerGastric Cancer
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Study completedNCT00002984
What this trial is testing

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced or Metastatic Cancer of the Esophagus

Who this might be right for
Esophageal Cancer
UNC Lineberger Comprehensive Cancer Center 26
Testing effectiveness (Phase 2)Ended earlyNCT00093652
What this trial is testing

Oxaliplatin, Gefitinib, and Radiation Therapy in Treating Patients With Locally Advanced or Metastatic Esophageal Cancer

Who this might be right for
Esophageal Cancer
Roswell Park Cancer Institute
Early research (Phase 1)Active Not RecruitingNCT04603287
What this trial is testing

SI-B001, an EGFR/HER3 Bispecific Antibody, in Locally Advanced or Metastatic Epithelial Tumors

Who this might be right for
Locally Advanced or Metastatic Epithelial Tumor
Sichuan Baili Pharmaceutical Co., Ltd. 60
Testing effectiveness (Phase 2)Ended earlyNCT04032704
What this trial is testing

Ladiratuzumab Vedotin in Advanced Solid Tumors

Who this might be right for
Small Cell Lung CancerNon-small Cell Lung Cancer, SquamousNon-small Cell Lung Cancer, Non-squamous+6 more
Seagen Inc. 205
Early research (Phase 1)Looking for participantsNCT07390838
What this trial is testing

SH009 Injection in Patients With Advanced Solid Tumors.

Who this might be right for
Liver Cancer (Locally Advanced or Metastatic)Lung Cancer (NSCLC)Head and Neck Cancer Squamous Cell Carcinoma+4 more
Nanjing Sanhome Pharmaceutical, Co., Ltd. 150
Testing effectiveness (Phase 2)Looking for participantsNCT06780111
What this trial is testing

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Who this might be right for
Esophageal Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 298
Testing effectiveness (Phase 2)Ended earlyNCT05461794
What this trial is testing

Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
BeiGene 96
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07128693
What this trial is testing

A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06703047
What this trial is testing

Tislelizumab Combined with Chemotherapy and All Trans Retinoic Acid for Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Fudan University 180
Testing effectiveness (Phase 2)UnknownNCT06055153
What this trial is testing

DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC

Who this might be right for
Esophageal Squamous CarcinomaHER-2 Protein Overexpression
Changhai Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT07733180
What this trial is testing

A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCC

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaMetastatic Esophageal Squamous Cell Carcinoma
BeOne Medicines 30
Large-scale testing (Phase 3)Looking for participantsNCT07487896
What this trial is testing

YL201 Versus Investigator's Choice of Chemotherapy in Participants With Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-Line Therapy

Who this might be right for
Advanced Esophageal Squamous Cell Carcinoma
MediLink Therapeutics (Suzhou) Co., Ltd. 440
Large-scale testing (Phase 3)Study completedNCT03783442
What this trial is testing

Tislelizumab (BGB-A317) in Combination With Chemotherapy as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
BeiGene 649
Testing effectiveness (Phase 2)Study completedNCT00016900
What this trial is testing

PNU-93914 in Treating Patients With Locally Advanced or Metastatic Cancer of the Esophagus

Who this might be right for
Esophageal Cancer
Memorial Sloan Kettering Cancer Center
Large-scale testing (Phase 3)Looking for participantsNCT04415853
What this trial is testing

Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer

Who this might be right for
Esophageal Cancer
Sunshine Lake Pharma Co., Ltd. 416
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