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Results for “Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma”

58 trials

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Showing 20 of 58 results

Testing effectiveness (Phase 2)Looking for participantsNCT06780111
What this trial is testing

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Who this might be right for
Esophageal Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 298
Testing effectiveness (Phase 2)UnknownNCT06055153
What this trial is testing

DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC

Who this might be right for
Esophageal Squamous CarcinomaHER-2 Protein Overexpression
Changhai Hospital 20
Early research (Phase 1)Looking for participantsNCT07390838
What this trial is testing

SH009 Injection in Patients With Advanced Solid Tumors.

Who this might be right for
Liver Cancer (Locally Advanced or Metastatic)Lung Cancer (NSCLC)Head and Neck Cancer Squamous Cell Carcinoma+4 more
Nanjing Sanhome Pharmaceutical, Co., Ltd. 150
Testing effectiveness (Phase 2)Looking for participantsNCT06339619
What this trial is testing

Combination Immunotherapy of Adebrelimab With Apatinib and Tegafur for Immune Rechallenge Therapy in Esophageal Squamous Cell Carcinoma

Who this might be right for
Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 32
Early research (Phase 1)Active Not RecruitingNCT04603287
What this trial is testing

SI-B001, an EGFR/HER3 Bispecific Antibody, in Locally Advanced or Metastatic Epithelial Tumors

Who this might be right for
Locally Advanced or Metastatic Epithelial Tumor
Sichuan Baili Pharmaceutical Co., Ltd. 60
Testing effectiveness (Phase 2)Study completedNCT00006245
What this trial is testing

Flavopiridol and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Esophageal Cancer That Has Not Responded to Previous Paclitaxel

Who this might be right for
Esophageal Cancer
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Looking for participantsNCT05581004
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid TumorsNSCLCHNSCC+9 more
Genentech, Inc. 450
Early research (Phase 1)UnknownNCT05927844
What this trial is testing

XH-30002 Capsule Combined With Afatinib Tablets for the Treatment of Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Fujian Cancer Hospital 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07128693
What this trial is testing

A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 60
Testing effectiveness (Phase 2)Study completedNCT00003055
What this trial is testing

Cisplatin and Irinotecan in Treating Patients With Locally Advanced or Metastatic Esophageal or Gastric Cancer

Who this might be right for
Esophageal CancerGastric Cancer
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)UnknownNCT05221658
What this trial is testing

A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy or Monotherapy in Patients With Advanced ESCC

Who this might be right for
ESCC or Esophageal Adenosquamous Carcinoma
Shanghai Henlius Biotech 60
Early research (Phase 1)Study completedNCT04641871
What this trial is testing

Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies

Who this might be right for
Metastatic CancerSolid Tumor
Symphogen A/S 78
Large-scale testing (Phase 3)Study completedNCT04540211
What this trial is testing

Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Carcinoma

Who this might be right for
Esophageal Cancer
Hoffmann-La Roche 461
Testing effectiveness (Phase 2)Looking for participantsNCT05267626
What this trial is testing

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
Advanced Solid TumorMetastatic CancerCutaneous Melanoma+1 more
Aulos Bioscience, Inc. 159
Testing effectiveness (Phase 2)Study completedNCT04732494
What this trial is testing

Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
BeiGene 125
Early research (Phase 1)Study completedNCT04925284
What this trial is testing

Study of XB002 in Subjects With Solid Tumors (JEWEL-101)

Who this might be right for
Non Small Cell Lung CancerCervical CancerSCCHN+8 more
Exelixis 269
Testing effectiveness (Phase 2)Ended earlyNCT05461794
What this trial is testing

Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
BeiGene 96
Testing effectiveness (Phase 2)Active Not RecruitingNCT04225117
What this trial is testing

Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 329
Testing effectiveness (Phase 2)Active Not RecruitingNCT05945823
What this trial is testing

Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors Including Esophageal CancerEsophageal AdenocarcinomaEsophageal Squamous Cell Cancer+2 more
Taiho Oncology, Inc. 53
Early research (Phase 1)Looking for participantsNCT07218003
What this trial is testing

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

Who this might be right for
Non Small Cell Lung CancerCervical CancerHead and Neck Squamous Cell Cancer+7 more
Rondo Therapeutics 149
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