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Results for “Locally Advanced or Metastatic and Unresectable HCC”

34 trials

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Showing 20 of 34 results

Testing effectiveness (Phase 2)Looking for participantsNCT07227012
What this trial is testing

Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

Who this might be right for
Carcinoma, HepatocellularHepatocellular CancerHepatocellular Carcinoma+4 more
Pfizer 138
Testing effectiveness (Phase 2)Study completedNCT03941873
What this trial is testing

Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma or Gastric/Gastroesophageal Junction Cancer

Who this might be right for
Carcinoma, HepatocellularGastric/Gastroesophageal Junction Cancer
BeiGene 111
Large-scale testing (Phase 3)Ended earlyNCT00658593
What this trial is testing

Gemcitabine With/Out Capecitabine in Locally Advanced, Unresectable, or Metastatic Biliary Cancer

Who this might be right for
Extrahepatic Bile Duct CancerGallbladder CancerLiver Cancer
NCIC Clinical Trials Group 19
Testing effectiveness (Phase 2)Study completedNCT03439891
What this trial is testing

Sorafenib and Nivolumab in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v7+4 more
Robin Kate Kelley 16
Early research (Phase 1)Ended earlyNCT00767468
What this trial is testing

Sorafenib in Treating Patients With Locally Advanced or Metastatic Liver Cancer and Cirrhosis

Who this might be right for
Liver Cancer
UNC Lineberger Comprehensive Cancer Center 6
Testing effectiveness (Phase 2)Ended earlyNCT00427973
What this trial is testing

AZD2171 in Treating Patients With Locally Advanced Unresectable or Metastatic Liver Cancer

Who this might be right for
Adult Primary Hepatocellular CarcinomaAdvanced Adult Primary Liver CancerLocalized Unresectable Adult Primary Liver Cancer+1 more
National Cancer Institute (NCI) 17
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06196775
What this trial is testing

Cadonilimab Combined With AK112 as Second-line Therapy in Patients With Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Harbin Medical University 36
Testing effectiveness (Phase 2)Looking for participantsNCT05733598
What this trial is testing

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

Who this might be right for
Hepatocellular CarcinomaBiliary Tract Cancer
Replimune Inc. 60
Early research (Phase 1)Study completedNCT02572687
What this trial is testing

Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies

Who this might be right for
Gastric CancerGastroesophageal Junction AdenocarcinomaNon-Small Cell Lung Cancer+1 more
Eli Lilly and Company 85
Testing effectiveness (Phase 2)Active Not RecruitingNCT05620134
What this trial is testing

Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
CancerTumor, SolidAdvanced Solid Tumor+19 more
Salubris Biotherapeutics Inc 263
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05897138
What this trial is testing

Evaluate Lenvatinib Plus Tislelizumab for Locally Advanced Unresectable or Metastatic Hepatocellular Carcinoma With Hepatitis B Virus Infection and Biomarker Analyses

Who this might be right for
Hepatocellular Carcinoma
Fujian Cancer Hospital 30
Large-scale testing (Phase 3)Study completedNCT01015833
What this trial is testing

Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer

Who this might be right for
Advanced Adult Hepatocellular CarcinomaRecurrent Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v7+7 more
National Cancer Institute (NCI) 356
Testing effectiveness (Phase 2)Looking for participantsNCT05168163
What this trial is testing

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Who this might be right for
Locally Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+6 more
Academic and Community Cancer Research United 122
Early research (Phase 1)Study completedNCT02595866
What this trial is testing

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Who this might be right for
AIDS-Related Non-Hodgkin LymphomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+16 more
National Cancer Institute (NCI) 58
Large-scale testing (Phase 3)Study completedNCT03764293
What this trial is testing

Evaluate SHR-1210 in Combination With Apatinib as First-Line Therapy in Patients With Advanced HCC

Who this might be right for
Locally Advanced or Metastatic and Unresectable HCC
Jiangsu HengRui Medicine Co., Ltd. 543
Testing effectiveness (Phase 2)Study completedNCT03044587
What this trial is testing

Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer

Who this might be right for
Adenocarcinoma MetastaticBiliary Tract CancerAdenocarcinoma of the Biliary Tract+4 more
AIO-Studien-gGmbH 93
Testing effectiveness (Phase 2)Study completedNCT00941967
What this trial is testing

Sorafenib With or Without Gemcitabine and Oxaliplatin in Treating Patients With Locally Advanced, Unresectable, or Metastatic Liver Cancer

Who this might be right for
Liver Cancer
Institut du Cancer de Montpellier - Val d'Aurelle 78
Testing effectiveness (Phase 2)Looking for participantsNCT05440708
What this trial is testing

TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Tvardi Therapeutics, Incorporated 178
Early research (Phase 1)Study completedNCT00010023
What this trial is testing

Capecitabine Combined With Cisplatin in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Cancer
NYU Langone Health
Not applicableLooking for participantsNCT07223411
What this trial is testing

Opdualag vs. Cemiplimab/Fianlimab in Relation to the Immunological Response in Tumor and Peripheral Blood in Unresectable or Metastatic Melanoma

Who this might be right for
Locally Advanced Melanoma
John Kirkwood 20
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