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Results for “Locally Metastatic Malignant Neoplasm”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT07018570
What this trial is testing

An Open Label Phase 2 Study of Total Neoadjuvant Therapy (TNT) Consisting of FLOT With Pembrolizumab and Short Radiation for Patients With Locally Advanced Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastroesophageal Junction (GEJ) Adenocarcinoma
National Cancer Center Hospital East 26
Large-scale testing (Phase 3)Looking for participantsNCT06345729
What this trial is testing

Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

Who this might be right for
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 600
Not applicableActive Not RecruitingNCT03281902
What this trial is testing

Genetic Analysis in Blood and Tumor Samples From Patients With Advanced or Metastatic Estrogen Receptor Positive and HER2 Negative Breast Cancer Receiving Palbociclib and Endocrine Therapy

Who this might be right for
Advanced Breast CarcinomaLocally Advanced Breast CarcinomaMetastatic Breast Carcinoma+6 more
Mayo Clinic 68
Large-scale testing (Phase 3)Looking for participantsNCT06838273
What this trial is testing

BL-B01D1 in Combination With Osimertinib Versus Osimertinib as First-Line Treatment in Patients With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer(PANKU-Lung04)

Who this might be right for
Non-small Cell Lung Cancer
Sichuan Baili Pharmaceutical Co., Ltd. 720
Testing effectiveness (Phase 2)Ended earlyNCT04424641
What this trial is testing

A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumor(s)Prostate CancerEsophageal Cancer+5 more
Genmab 48
Early research (Phase 1)Study completedNCT02350673
What this trial is testing

Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 70
Early research (Phase 1)Ended earlyNCT02346370
What this trial is testing

A Phase 1b Study of PEGylated Recombinant Human Hyaluronidase (PEGPH20) Combined With Docetaxel in Subjects With Recurrent Previously Treated Locally Advanced or Metastatic NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Halozyme Therapeutics 16
Very early researchActive Not RecruitingNCT06853769
What this trial is testing

Neoadjuvant Therapy for Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 48
Not applicableEnrolling By InvitationNCT04195503
What this trial is testing

Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma

Who this might be right for
Cholangiocarcinoma, Intrahepatic
University Health Network, Toronto 10
Large-scale testing (Phase 3)Active Not RecruitingNCT00569127
What this trial is testing

Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor

Who this might be right for
Colorectal Neuroendocrine Tumor G1Gastric Neuroendocrine Tumor G1Neuroendocrine Neoplasm+2 more
National Cancer Institute (NCI) 427
Early research (Phase 1)Looking for participantsNCT07027488
What this trial is testing

AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Melanoma and Normal or ImpairedAdvanced Melanoma
Yale University 50
Early research (Phase 1)Looking for participantsNCT05136846
What this trial is testing

Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

Who this might be right for
Locally Advanced Lung Non-Small Cell CarcinomaStage II Lung Cancer AJCC v8Stage IIA Lung Cancer AJCC v8+6 more
Ohio State University Comprehensive Cancer Center 28
Testing effectiveness (Phase 2)Looking for participantsNCT06761027
What this trial is testing

MFOLFIRINOX Plus Anlotinib and Sintilimab for Advanced Pancreatic Cancer

Who this might be right for
Locally Advanced Pancreatic CancerMetastatic Pancreatic Cancer
Fujian Provincial Hospital 29
Testing effectiveness (Phase 2)Study completedNCT04504942
What this trial is testing

Basket Study of Leronlimab (PRO 140) in Patients With CCR5+ Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumor, Adult
CytoDyn, Inc. 16
Testing effectiveness (Phase 2)Study completedNCT00382720
What this trial is testing

Docetaxel and Oxaliplatin in Gastric Cancer

Who this might be right for
Stomach Neoplasms
Sanofi 275
Testing effectiveness (Phase 2)Study completedNCT00222469
What this trial is testing

Combination Chemotherapy for 1st Line Treatment of Advanced or Metastatic Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Cancer
University of Oklahoma 50
Testing effectiveness (Phase 2)UnknownNCT01234051
What this trial is testing

Docetaxel and Oxaliplatin Combination With Locally Advanced or Metastatic Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
Korean South West Oncology Group 53
Testing effectiveness (Phase 2)Active Not RecruitingNCT06041802
What this trial is testing

Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) (Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180)) in Japanese Participants With Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC) or Locally Advanced (LA) Unresectable cSCC (MK-3475A-E39)

Who this might be right for
Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 19
Testing effectiveness (Phase 2)UnknownNCT06178601
What this trial is testing

RC48-ADC Combined With Cadonilimab（AK104）in the Treatment of HER2-expression Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Shanxi Province Cancer Hospital 36
Testing effectiveness (Phase 2)Looking for participantsNCT06385730
What this trial is testing

Neoadjuvant PD-1 Blockade for Elderly Esophageal Squamous Cell Carcinoma (BLESS)

Who this might be right for
Esophageal Cancer
Shanghai Chest Hospital 60
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