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Results for “Locally Recurrent Skin Squamous Cell Carcinoma”

20 trials

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Showing 20 of 20 results

Testing effectiveness (Phase 2)Temporarily pausedNCT07042295
What this trial is testing

Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System

Who this might be right for
Locally Recurrent Skin Squamous Cell CarcinomaMetastatic Skin Squamous Cell Carcinoma
National Cancer Institute (NCI) 86
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT01598597
What this trial is testing

An Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizing Subject Provided Information in Subjects With Locally Recurrent or MBC, MCRC, MNSCLC, RGBM or MRCC Treated With Avastin (Bevacizumab) (InVite)

Who this might be right for
Breast CancerColorectal CancerNon-Small Cell Lung Cancer+2 more
Genentech, Inc. 276
Testing effectiveness (Phase 2)Ended earlyNCT03435640
What this trial is testing

REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies

Who this might be right for
MelanomaMerkel Cell CarcinomaTriple Negative Breast Cancer+4 more
Nektar Therapeutics 64
Testing effectiveness (Phase 2)Looking for participantsNCT06682793
What this trial is testing

Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNon-Small Cell Lung+14 more
A2 Biotherapeutics Inc. 240
Testing effectiveness (Phase 2)Ended earlyNCT04242173
What this trial is testing

Cemiplimab-rwlc for Unresectable Locally Recurrent and/or Metastatic CSCC

Who this might be right for
Cutaneous Squamous Cell CarcinomaCutaneous Squamous Cell Carcinoma of the Head and Neck
H. Lee Moffitt Cancer Center and Research Institute 3
Not applicableStudy completedNCT02324608
What this trial is testing

Cetuximab Before Surgery in Treating Patients With Aggressive Locally Advanced Skin Cancer

Who this might be right for
Recurrent Skin CancerSquamous Cell Carcinoma of the Skin
Rutgers, The State University of New Jersey 15
Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Study completedNCT02964559
What this trial is testing

Pembrolizumab in Patients With Locally Advanced or Metastatic Skin Cancer

Who this might be right for
Recurrent Skin CarcinomaSkin Squamous Cell Carcinoma
Emory University 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT04305795
What this trial is testing

An Open-label Study Using ASP-1929 Photoimmunotherapy in Combination With Anti-PD1 Therapy in EGFR Expressing Advanced Solid Tumors

Who this might be right for
Recurrent Head and Neck Squamous Cell CarcinomaMetastatic Head-and-neck Squamous-cell CarcinomaLocally Advanced Cutaneous Squamous Cell Carcinoma+1 more
Rakuten Medical, Inc. 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT04315701
What this trial is testing

A PD-1 Checkpoint Inhibitor (Cemiplimab) for High-Risk Localized, Locally Recurrent, or Regionally Advanced Skin Cancer

Who this might be right for
Recurrent Skin Squamous Cell CarcinomaResectable Skin Squamous Cell CarcinomaStage I Skin Cancer+2 more
University of Southern California 35
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Study completedNCT03284424
What this trial is testing

Study of Pembrolizumab (MK-3475) in Adults With Recurrent/Metastatic Cutaneous Squamous Cell Carcinoma (cSCC) or Locally Advanced Unresectable cSCC (MK-3475-629/KEYNOTE-629)

Who this might be right for
Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 159
Testing effectiveness (Phase 2)Study completedNCT04454489
What this trial is testing

Quad Shot Radiotherapy in Combination With Immune Checkpoint Inhibition

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaRecurrent Head and Neck Squamous Cell CarcinomaMetastatic Head-and-neck Squamous-cell Carcinoma+3 more
Wake Forest University Health Sciences 21
Testing effectiveness (Phase 2)Study completedNCT00126555
What this trial is testing

Gefitinib in Treating Patients Who Are Undergoing Surgery and/or Radiation Therapy for Locally Advanced or Recurrent Squamous Cell Skin Cancer

Who this might be right for
Recurrent Skin CancerSquamous Cell Carcinoma of the Skin
National Cancer Institute (NCI) 23
Early research (Phase 1)Study completedNCT02051751
What this trial is testing

Evaluate the Potential Benefit of the Addition of BYL719 to Paclitaxel in the Treatment of Breast Cancer and Head-and-neck Cancer

Who this might be right for
Neoplasms, Breast Neoplasms, Head and Neck Neoplasms
Novartis Pharmaceuticals 19
Testing effectiveness (Phase 2)Active Not RecruitingNCT06041802
What this trial is testing

Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) (Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180)) in Japanese Participants With Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC) or Locally Advanced (LA) Unresectable cSCC (MK-3475A-E39)

Who this might be right for
Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 19
Early research (Phase 1)Ended earlyNCT04163952
What this trial is testing

Talimogene Laherparepvec and Panitumumab for the Treatment of Locally Advanced or Metastatic Squamous Cell Carcinoma of the Skin

Who this might be right for
Locally Advanced Skin Squamous Cell CarcinomaMetastatic Skin Squamous Cell CarcinomaRecurrent Skin Squamous Cell Carcinoma
Rutgers, The State University of New Jersey 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT06580054
What this trial is testing

Pembrolizumab for the Treatment of Locally Advanced and/or Recurrent Orbital or Periocular Cutaneous Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and NeckRecurrent Cutaneous Squamous Cell Carcinoma of the Head and NeckStage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
University of Michigan Rogel Cancer Center 3
Early research (Phase 1)Study completedNCT00010023
What this trial is testing

Capecitabine Combined With Cisplatin in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Cancer
NYU Langone Health
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