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Results for “Loss of Chromosome 17p”

21 trials

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Showing 20 of 21 results

Testing effectiveness (Phase 2)Study completedNCT02633059
What this trial is testing

Idasanutlin, Ixazomib Citrate, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma

Who this might be right for
Loss of Chromosome 17pRecurrent Plasma Cell Myeloma
Mayo Clinic 33
Testing effectiveness (Phase 2)Study completedNCT02420912
What this trial is testing

Nivolumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or High-Risk Untreated Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Richter Transformation

Who this might be right for
Loss of Chromosome 17pRecurrent Chronic Lymphocytic LeukemiaRecurrent Small Lymphocytic Lymphoma+3 more
M.D. Anderson Cancer Center 37
Testing effectiveness (Phase 2)WithdrawnNCT03943342
What this trial is testing

Ibrutinib and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia After Ibrutinib Resistance

Who this might be right for
Chronic Lymphocytic LeukemiaLoss of Chromosome 17p
Kerry Rogers
Testing effectiveness (Phase 2)Study completedNCT01889186
What this trial is testing

The Efficacy of ABT-199 in Subjects With Relapsed/Refractory or Previously Untreated Chronic Lymphocytic Leukemia With the 17p Deletion

Who this might be right for
Chronic Lymphocytic Leukemia17p DeletionCancer of the Blood and Bone Marrow
AbbVie 158
Large-scale testing (Phase 3)Study completedNCT02980731
What this trial is testing

A Study Evaluating the Impact of Venetoclax on the Quality of Life for Subjects With Relapsed (Your Cancer Has Come Back) or Refractory (no Response to Previous Cancer Treatments) Chronic Lymphocytic Leukemia (CLL) While Receiving Venetoclax Monotherapy (a Single Agent).

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)
AbbVie 210
Early research (Phase 1)Study completedNCT01163357
What this trial is testing

Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma

Who this might be right for
Autologous Hematopoietic Stem Cell Transplant RecipientLoss of Chromosome 17pPlasma Cell Leukemia+2 more
City of Hope Medical Center 18
Testing effectiveness (Phase 2)Study completedNCT01008462
What this trial is testing

Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia

Who this might be right for
B-Cell Prolymphocytic LeukemiaHypodiploidyLoss of Chromosome 17p+18 more
Fred Hutchinson Cancer Center 16
Very early researchEnded earlyNCT03272633
What this trial is testing

Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia in RemissionHematopoietic Cell Transplantation Recipient+16 more
Rutgers, The State University of New Jersey 2
Large-scale testing (Phase 3)Study completedNCT03406156
What this trial is testing

A Study in Previously Untreated Chronic Lymphocytic Leukemia (CLL) Subjects, Excluding Those With the 17p Deletion, to Evaluate Debulking Regimens Prior to Initiating Venetoclax Combination Therapy

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)
AbbVie 120
Testing effectiveness (Phase 2)Active Not RecruitingNCT02966756
What this trial is testing

Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)
AbbVie 66
Post-approval studies (Phase 4)Study completedNCT03190330
What this trial is testing

Assess Safety of ImbruvicaTM in Indian Participants With Chronic Lymphocytic Leukemia or Mantle Cell Lymphoma Who Have Received at Least One Prior Therapy or Chronic Lymphocytic Leukemia With 17p Deletion

Who this might be right for
Leukemia, Lymphocytic, Chronic, B-CellLymphoma, Mantle-Cell
Johnson & Johnson Private Limited 75
Large-scale testing (Phase 3)Study completedNCT02756611
What this trial is testing

Evaluate the Efficacy of Venetoclax Monotherapy in Relapsed/Refractory Participants With Chronic Lymphocytic Leukemia (CLL)

Who this might be right for
Chronic Lymphocytic Leukemia
AbbVie 258
Testing effectiveness (Phase 2)Study completedNCT01392079
What this trial is testing

Subcutaneous Alemtuzumab Combined With Oral Dexamethasone, Followed by Alemtuzumab Maintenance or Allo-SCT in CLL With 17p- or Refractory to Fludarabine

Who this might be right for
Chronic Lymphocytic Leukemia
University of Ulm 135
Not applicableLooking for participantsNCT04463316
What this trial is testing

GROWing Up With Rare GENEtic Syndromes

Who this might be right for
Prader-Willi SyndromePWS-like SyndromeSilver Russel Syndrome+30 more
dr. Laura C. G. de Graaff-Herder 600
Testing effectiveness (Phase 2)Active Not RecruitingNCT01500733
What this trial is testing

PCI-32765 for Special Cases of Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Who this might be right for
LeukemiaLeukemia, LymphocytycCLL (Chronic Lymphocytic Leukemia)+1 more
National Heart, Lung, and Blood Institute (NHLBI) 86
Not applicableUnknownNCT04008888
What this trial is testing

A Clinical Trial of Efficacy and Safety of the Holistic Treatment of Young High-risk Multiple Myeloma Patients

Who this might be right for
Multiple MyelomaPlasma Cell LeukemiaExtramedullary Plasmacytoma+6 more
Institute of Hematology & Blood Diseases Hospital, China 50
Testing effectiveness (Phase 2)Study completedNCT02337829
What this trial is testing

Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Acerta Pharma BV 48
Testing effectiveness (Phase 2)Ended earlyNCT02044822
What this trial is testing

Efficacy and Safety of Idelalisib in Combination With Rituximab in Patients With Previously Untreated Chronic Lymphocytic Leukemia With 17p Deletion

Who this might be right for
B-cell Chronic Lymphocytic Leukemia (CLL) With 17p Deletion
Gilead Sciences 102
Testing effectiveness (Phase 2)Ended earlyNCT01465334
What this trial is testing

Ofatumumab With High Dose Methylprednisone Followed by Ofatumumab and Alemtuzumab in 17p CLL

Who this might be right for
CLLSLL
Dana-Farber Cancer Institute 30
Testing effectiveness (Phase 2)Study completedNCT01527045
What this trial is testing

Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies

Who this might be right for
Aggressive Non-Hodgkin LymphomaBlasts Under 5 Percent of Bone Marrow Nucleated CellsChronic Lymphocytic Leukemia+18 more
Fred Hutchinson Cancer Center 47
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