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Results for “Lower-risk Myelodysplastic Syndromes”

60 trials

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Showing 20 of 60 results

Early research (Phase 1)Study completedNCT05030675
What this trial is testing

Fostamatinib for the Treatment of Lower-risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia Who Have Failed Therapy With Hypomethylating Agents

Who this might be right for
Refractory Chronic Myelomonocytic LeukemiaRefractory Myelodysplastic Syndrome
M.D. Anderson Cancer Center 11
Testing effectiveness (Phase 2)Temporarily pausedNCT04539236
What this trial is testing

Luspatercept and Lenalidomide (L2) in Lower-risk, Non-del(5q) MDS Patients

Who this might be right for
Myelodysplastic Syndromes
Mikkael Sekeres, MD 50
Testing effectiveness (Phase 2)Ended earlyNCT02469415
What this trial is testing

Pacritinib for Patients With Lower-Risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT06243458
What this trial is testing

RVU120 for Treatment of Anemia in Patients With Lower-risk Myelodysplastic Neoplasms

Who this might be right for
Low Risk Myelodysplastic Syndromes
GCP-Service International West GmbH 41
Testing effectiveness (Phase 2)Looking for participantsNCT07579429
What this trial is testing

Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial)

Who this might be right for
Clonal Cytopenia of Undetermined SignificanceMyelodysplastic Syndrome
University of Colorado, Denver 10
Testing effectiveness (Phase 2)Looking for participantsNCT05308264
What this trial is testing

Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)

Who this might be right for
Low Risk Myelodysplastic Syndromes
Rigel Pharmaceuticals 86
Testing effectiveness (Phase 2)WithdrawnNCT02431351
What this trial is testing

Efficacy & Safety Study of KPT-330 in Erythropoietin-Refractory Lower-Risk Myelodysplastic Syndrome Patients

Who this might be right for
Myelodysplastic Syndrome
Karyopharm Therapeutics Inc
Testing effectiveness (Phase 2)Active Not RecruitingNCT04798339
What this trial is testing

Canakinumab With Darbepoetin Alfa in PTs With Lower-Risk MDS Who Have Failed ESA

Who this might be right for
Myelodysplastic Syndromes
H. Lee Moffitt Cancer Center and Research Institute 13
Not applicableNot Yet RecruitingNCT07752121
What this trial is testing

First-Line Luspatercept in Transfusion-Dependent Lower-Risk Myelodysplastic Neoplasms

Who this might be right for
Myelodysplastic Neoplasms
Bristol-Myers Squibb 190
Testing effectiveness (Phase 2)Study completedNCT02363491
What this trial is testing

A Phase I/II Study of OPN-305 in Second-line Lower Risk Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndrome
Opsona Therapeutics Ltd. 96
Testing effectiveness (Phase 2)Looking for participantsNCT05384691
What this trial is testing

Efficacy of Luspatercept in ESA-naive LR-MDS Patients With or Without Ring Sideroblasts Who do Not Require Transfusions

Who this might be right for
Myelodysplastic SyndromesAnemia
University of Leipzig 213
Large-scale testing (Phase 3)Study completedNCT03303066
What this trial is testing

Efficacy and Safety of FG-4592 for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
AnemiaMyelodysplastic Syndrome
Kyntra Bio 43
Testing effectiveness (Phase 2)Active Not RecruitingNCT04797000
What this trial is testing

Study of Efficacy and Safety of Eltrombopag in Lower-risk MDS Patients With Platelet Transfusion Dependence

Who this might be right for
Myelodysplastic Syndromes
Novartis Pharmaceuticals 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT06098326
What this trial is testing

CyFluATG in Lower Risk MDS

Who this might be right for
Myelodysplastic Syndromes
Asan Medical Center 30
Testing effectiveness (Phase 2)UnknownNCT01652781
What this trial is testing

5 Day Versus 7 Day Azacitidine in Lower Risk Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndrome
Seoul St. Mary's Hospital 92
Early research (Phase 1)Study completedNCT03573310
What this trial is testing

JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

Who this might be right for
NeoplasmsSolid Tumor, AdultNon-Hodgkin Lymphoma+1 more
Janssen Research & Development, LLC 114
Testing effectiveness (Phase 2)UnknownNCT05392647
What this trial is testing

Hetrombopag for Lower-risk MDS With Thrombocytopenia: a Prospective，Open-label, Single-arm Study.

Who this might be right for
Myelodysplastic Syndromes
Tongji Hospital 28
Post-approval studies (Phase 4)Not Yet RecruitingNCT07830004
What this trial is testing

Plasmatic Biomarkers Associated With Short-term Luspatercept Treatment of Lower Risk Myelodysplastic Syndromes (MDS) Patients

Who this might be right for
Myelodysplasia
University Hospital, Grenoble 150
Not applicableStudy completedNCT06851065
What this trial is testing

Evaluate Luspatercept Treatment Patterns and Outcomes in Erythropoiesis-Stimulating Agents-Naïve Patients With Lower-Risk Myelodysplastic Syndromes in the United States

Who this might be right for
Myelodysplastic Syndromes
Bristol-Myers Squibb 418
Testing effectiveness (Phase 2)Study completedNCT02269280
What this trial is testing

Phase II Decitabine (DAC) Versus Azacitidine (AZA) in Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 185
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