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Results for “Lupus Nephritis (LN)”

65 trials

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Showing 20 of 65 results

Testing effectiveness (Phase 2)Looking for participantsNCT06585514
What this trial is testing

Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus (SLE)Lupus Nephritis (LN)
Beijing GoBroad Hospital 18
Very early researchLooking for participantsNCT06653556
What this trial is testing

LCAR-AIO in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus (SLE)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 34
Testing effectiveness (Phase 2)WithdrawnNCT06153095
What this trial is testing

IMPT-514 in Active Refractory Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE)

Who this might be right for
Systemic Lupus ErythematosusLupus Nephritis
Lyell Immunopharma, Inc.
Early research (Phase 1)Looking for participantsNCT07085104
What this trial is testing

Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

Who this might be right for
Systemic Lupus Erythematosus (With and Without Nephritis)Idiopathic Inflammatory MyopathySystemic Sclerosis
Allogene Therapeutics 54
Not applicableUnknownNCT04894695
What this trial is testing

Urine Exosomes to Identify Biomarkers for LN

Who this might be right for
Lupus Nephritis
RenJi Hospital 400
Testing effectiveness (Phase 2)Looking for participantsNCT06947460
What this trial is testing

CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH

Who this might be right for
Refractory Lupus NephritisSystemic SclerosisPrimary Sjogren's Syndrome Combined With Pulmonary Hypertension
Beijing GoBroad Hospital 45
Testing effectiveness (Phase 2)Looking for participantsNCT07038382
What this trial is testing

Evaluate the Efficacy, Safety, and Tolerability of Human Sialidase Fusion Protein (HLX79) in Combination With Rituximab Injection Versus Placebo in Patients With Active Glomerulonephritis

Who this might be right for
Membranous NephropathyLupus Nephritis (LN)
Shanghai Henlius Biotech 24
Early research (Phase 1)Not Yet RecruitingNCT06708845
What this trial is testing

US Zamto-cel Autoimmune Diseases

Who this might be right for
Lupus NephritisSystemic Lupus ErythematosusSystemic Sclerosis (SSc)+1 more
Miltenyi Biomedicine GmbH 48
Testing effectiveness (Phase 2)Ended earlyNCT05097989
What this trial is testing

Study of ALXN2050 in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

Who this might be right for
Lupus NephritisImmunoglobulin A NephropathyIgAN+1 more
Alexion Pharmaceuticals, Inc. 100
Testing effectiveness (Phase 2)UnknownNCT02682407
What this trial is testing

Safety Study of IgAN, LN, MN, & C3 Glomerulopathy Including Dense Deposit Disease Treated With OMS721

Who this might be right for
IgANLupus NephritisMN+1 more
Omeros Corporation 54
Testing effectiveness (Phase 2)Ended earlyNCT04564339
What this trial is testing

Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

Who this might be right for
Lupus NephritisImmunoglobulin A Nephropathy
Alexion Pharmaceuticals, Inc. 123
Not applicableNot Yet RecruitingNCT06288308
What this trial is testing

Fibrinogen to Albumin Ratio (FAR) as a Predictive Biomarker for Lupus Nephritis (LN)

Who this might be right for
Lupus Nephritis
Assiut University 90
Large-scale testing (Phase 3)Ended earlyNCT04181762
What this trial is testing

Study of Safety, Efficacy and Tolerability of Secukinumab Versus Placebo, in Combination With SoC Therapy, in Patients With Active Lupus Nephritis

Who this might be right for
Lupus Nephritis
Novartis Pharmaceuticals 275
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07328581
What this trial is testing

BCMA-CD19 cCAR T for the Treatment of Refractory Lupus

Who this might be right for
Systemic Lupus Erythematosus (SLE)Lupus Nephritis (LN)
iCell Gene Therapeutics 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06947473
What this trial is testing

Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.

Who this might be right for
Refractory Lupus NephritisSystemic SclerosisPrimary Sjogren's Syndrome Combined With Pulmonary Hypertension
Beijing GoBroad Hospital 45
Post-approval studies (Phase 4)Ended earlyNCT01861561
What this trial is testing

Low-dose VS High-dose IV Cyclophosphamide for Proliferative LN in Children

Who this might be right for
Renal InsufficiencyInfection
Mahidol University 43
Early research (Phase 1)Not Yet RecruitingNCT07104721
What this trial is testing

A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases

Who this might be right for
Systemic Lupus Erythematosus (SLE)Lupus Nephritis (LN)Systemic Sclerosis (SSc)+3 more
China Immunotech (Beijing) Biotechnology Co., Ltd. 18
Not applicableStudy completedNCT03664908
What this trial is testing

Detection of Anti-glomerular Basement Membrane Antibodies (Anti-GBM): a Promising Biomarker for Lupus Nephritis (LN)?

Who this might be right for
Lupus Nephritis
CHU de Reims 100
Testing effectiveness (Phase 2)Looking for participantsNCT06839976
What this trial is testing

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

Who this might be right for
SLESystemic Lupus Erythematosus (SLE)CAR T Cell+4 more
Children's Hospital of Philadelphia 24
Large-scale testing (Phase 3)UnknownNCT05631717
What this trial is testing

The Study of Comparing the Efficacy and Safety of Human Umbilical Cord MSCs and Low-dose IL-2 in the Treatment of LN

Who this might be right for
Systemic Lupus ErythematosusLupus Nephritis
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 40
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