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Results for “MDS/MPN”

51 trials

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Showing 20 of 51 results

Testing effectiveness (Phase 2)Looking for participantsNCT04996875
What this trial is testing

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Who this might be right for
Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc. 140
Not applicableLooking for participantsNCT06211166
What this trial is testing

Assessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain Reaction

Who this might be right for
Acute LeukemiaMDSMDS/MPN+1 more
Peking University People's Hospital 300
Testing effectiveness (Phase 2)Ended earlyNCT02711137
What this trial is testing

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors
Incyte Corporation 137
Early research (Phase 1)Looking for participantsNCT05549661
What this trial is testing

Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms

Who this might be right for
Recurrent Chronic Myelomonocytic LeukemiaRefractory Chronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified+3 more
Mayo Clinic 25
Testing effectiveness (Phase 2)Ended earlyNCT05237713
What this trial is testing

Efficacy and Safety of Canakinumab for the Treatment of Anemia in LR-MDS Patients

Who this might be right for
AnemiaMyelodysplastic Syndromes
University of Leipzig 10
Testing effectiveness (Phase 2)Study completedNCT01606579
What this trial is testing

Safety and Efficacy Study of PRI-724 in Subjects With Advanced Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaChronic Myeloid Leukemia
Prism Pharma Co., Ltd. 49
Not applicableLooking for participantsNCT07143669
What this trial is testing

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

Who this might be right for
Clonal Mast Cell DiseaseKIT D816V MutationSuspected KITD816V Mutated Clonal Mast Cell Disease
Blueprint Medicines Corporation 450
Not applicableStudy completedNCT02775383
What this trial is testing

The National Myelodysplastic Syndromes (MDS) Study

Who this might be right for
Myelodysplastic Syndromes (MDS)
National Heart, Lung, and Blood Institute (NHLBI) 2,115
Early research (Phase 1)Study completedNCT05775406
What this trial is testing

Safety and Clinical Activity of KT-253 in Adult Patients with High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors

Who this might be right for
Myeloid MalignanciesAcute Lymphocytic LeukemiaLymphomas+1 more
Kymera Therapeutics, Inc. 52
Early research (Phase 1)Ended earlyNCT04637009
What this trial is testing

TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMyeloproliferative NeoplasmMyelodysplastic/Myeloproliferative Neoplasm
Astex Pharmaceuticals, Inc. 20
Early research (Phase 1)Study completedNCT02493530
What this trial is testing

TGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea

Who this might be right for
MyelofibrosisPolycythemia Vera
Vanderbilt-Ingram Cancer Center 60
Not applicableUnknownNCT02872662
What this trial is testing

Individual Molecular MRD Monitoring for MDS Patients After Allo-SCT

Who this might be right for
MDSSCTMRD
Nordic MDS Group 200
Early research (Phase 1)Looking for participantsNCT04771572
What this trial is testing

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Who this might be right for
Non Hodgkin LymphomaRichter TransformationMultiple Myeloma+10 more
Newave Pharmaceutical Inc 100
Early research (Phase 1)Study completedNCT04473911
What this trial is testing

Haplo Peripheral Blood Sct In GVHD Prevention

Who this might be right for
GVHDAMLALL+13 more
Zachariah Michael DeFilipp 25
Testing effectiveness (Phase 2)Study completedNCT02084563
What this trial is testing

Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMyeloproliferative NeoplasmsMyelodysplastic Syndromes+1 more
Hospital Israelita Albert Einstein 455
Early research (Phase 1)Study completedNCT02492737
What this trial is testing

Study of Orally Administered AG-881 in Patients With Advanced Hematologic Malignancies With an IDH1 and/or IDH2 Mutation

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic SyndromeHematologic Malignancies
Agios Pharmaceuticals, Inc. 46
Not applicableNot Yet RecruitingNCT07108023
What this trial is testing

Hematological Disorders in EHPVO Patients

Who this might be right for
Extrahepatic Portal Vein Obstruction (EHPVO)ThrombophiliaMyeloproliferative Neoplasms (MPN)+5 more
Rahab Nady 115
Testing effectiveness (Phase 2)Looking for participantsNCT06892223
What this trial is testing

Anti-NKG2A Monoclonal Antibody for AML or MDS Patients Undergoing Haploidentical Transplantation

Who this might be right for
Acute Myeloid LeukaemiaMDS (Myelodysplastic Syndrome)MPN (Myeloproliferative Neoplasms)
Istituto Clinico Humanitas 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT05600894
What this trial is testing

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromeMyelodysplastic Syndrome With Excess Blasts+2 more
National Cancer Institute (NCI) 132
Testing effectiveness (Phase 2)Ended earlyNCT04866056
What this trial is testing

Jaktinib and Azacitidine In Treating Patients With MDS With MF or MDS/MPN With MF.

Who this might be right for
Myelodysplastic SyndromesMyeloproliferative NeoplasmsMyelofibrosis
Suzhou Zelgen Biopharmaceuticals Co.,Ltd 1
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