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Results for “MDS/MPN”

58 trials

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Showing 20 of 58 results

Early research (Phase 1)Ended earlyNCT05609942
What this trial is testing

Study of Elenestinib (BLU-263) in Advanced Systemic Mastocytosis (AdvSM) and and Other KIT Altered Hematologic Malignancies

Who this might be right for
Advanced Systemic Mastocytosis
Blueprint Medicines Corporation 9
Testing effectiveness (Phase 2)Ended earlyNCT02587598
What this trial is testing

Study of INCB053914 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors
Incyte Corporation 97
Testing effectiveness (Phase 2)Study completedNCT03238248
What this trial is testing

Pevonedistat and Azacitidine in MDS or MDS/MPN Patients Who Fail Primary Therapy With DNA Methyl Transferase Inhibitors

Who this might be right for
Myelodysplastic SyndromesMyeloproliferative Neoplasm
Vanderbilt-Ingram Cancer Center 71
Testing effectiveness (Phase 2)Looking for participantsNCT07612280
What this trial is testing

Phase 1/ Phase 2 Study to Assess Safety and Efficacy of Orally Administered JBI-802 in Subjects With Myeloproliferative Neoplasms (MPN) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) With Thrombocytosis

Who this might be right for
Essential Thrombocythemia (ET)Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)Myeloproliferative Neoplasms (MPN)
Jubilant Therapeutics Inc. 30
Not applicableLooking for participantsNCT06211166
What this trial is testing

Assessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain Reaction

Who this might be right for
Acute LeukemiaMDSMDS/MPN+1 more
Peking University People's Hospital 300
Early research (Phase 1)Ended earlyNCT04637009
What this trial is testing

TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMyeloproliferative NeoplasmMyelodysplastic/Myeloproliferative Neoplasm
Astex Pharmaceuticals, Inc. 20
Large-scale testing (Phase 3)Looking for participantsNCT04064060
What this trial is testing

Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Who this might be right for
Myelodysplastic Syndromes (MDS)Beta-thalassemiaMyeloproliferative Neoplasm(MPN)-Associated Myelofibrosis
Celgene 665
Testing effectiveness (Phase 2)Active Not RecruitingNCT05732961
What this trial is testing

Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms

Who this might be right for
Myelodysplastic SyndromesMyeloproliferative NeoplasmAnemia
H. Lee Moffitt Cancer Center and Research Institute 6
Not applicableNot Yet RecruitingNCT07108023
What this trial is testing

Hematological Disorders in EHPVO Patients

Who this might be right for
Extrahepatic Portal Vein Obstruction (EHPVO)ThrombophiliaMyeloproliferative Neoplasms (MPN)+5 more
Rahab Nady 115
Early research (Phase 1)Study completedNCT04473911
What this trial is testing

Haplo Peripheral Blood Sct In GVHD Prevention

Who this might be right for
GVHDAMLALL+13 more
Zachariah Michael DeFilipp 25
Not applicableActive Not RecruitingNCT05582902
What this trial is testing

Study Investigating Patient-Reported Outcomes in Lower-risk MDS Patients

Who this might be right for
MDSMDS/MPN
University of Leipzig 60
Testing effectiveness (Phase 2)Looking for participantsNCT04771130
What this trial is testing

BGB-11417 in Participants With Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Neoplasm
BeOne Medicines 260
Early research (Phase 1)Study completedNCT05775406
What this trial is testing

Safety and Clinical Activity of KT-253 in Adult Patients with High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors

Who this might be right for
Myeloid MalignanciesAcute Lymphocytic LeukemiaLymphomas+1 more
Kymera Therapeutics, Inc. 52
Not applicableLooking for participantsNCT07680868
What this trial is testing

Caris Chromoseq Data Collection

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic (MDS) / Myeloproliferative (MPN) DiseasesMyelodysplatic Syndromes+1 more
Caris Science, Inc. 300
Testing effectiveness (Phase 2)Ended earlyNCT04639024
What this trial is testing

ADCT-301 in Patients With R/R AML, MDS, or MDS/MPN

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Myeloproliferative Neoplasm (MDS/MPN)
Gwynn Long, M.D. 3
Not applicableEnded earlyNCT01688011
What this trial is testing

Connect® Myeloid Disease Registry

Who this might be right for
Primary MyelofibrosisMyelodysplastic SyndromesLeukemia, Myeloid, Acute
Celgene 2,013
Testing effectiveness (Phase 2)Looking for participantsNCT06523556
What this trial is testing

Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm/Myelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic Leukemia

Who this might be right for
Atypical Chronic Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm+5 more
Uma Borate 49
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07468916
What this trial is testing

Ropeginterferon Alfa-2b for the Treatment of Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes and Chronic Myelomonocytic Leukemia

Who this might be right for
Atypical Chronic Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm+2 more
Jonsson Comprehensive Cancer Center 35
Early research (Phase 1)Ended earlyNCT05107856
What this trial is testing

PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignancies

Who this might be right for
Acute Myeloid LeukemiaB-cell Non-Hodgkin LymphomaChronic Lymphocytic Leukemia+7 more
Prelude Therapeutics Incorporated 21
Early research (Phase 1)Ended earlyNCT01066468
What this trial is testing

Glivec/Gleevec Pediatric (Age 1 to Less Than 4) PK Study in CML, Ph+ ALL Patients and Other Glivec/Gleevec® Indicated Hematological Disorders.

Who this might be right for
Chronic Myeloid Leukemia (CML)Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)Other Glivec/Gleevec Indicated Hematological Disorders (HES, CEL, MDS/ MPN)
Novartis Pharmaceuticals 3
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