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Results for “MGMT-Methylated Glioblastoma”

22 trials

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Showing 20 of 22 results

Testing effectiveness (Phase 2)Looking for participantsNCT06504381
What this trial is testing

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

Who this might be right for
High Grade GliomaMGMT-Unmethylated GlioblastomaMGMT-Methylated Glioblastoma
University of California, San Francisco 70
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07604285
What this trial is testing

Safety and Tolerability of MT-125 With Chemoradiation in Patients With Newly Diagnosed MGMT Methylated Glioblastoma

Who this might be right for
Glioblastoma
Myosin Therapeutics Inc. 36
Testing effectiveness (Phase 2)UnknownNCT01124240
What this trial is testing

Temozolomide and Procarbazine With Cilengitide for Patients With Glioblastoma Multiforme Without Methylation of the MGMT Promoter Gene

Who this might be right for
Newly Diagnosed Non Methylated Glioblastoma Multiforme Grade 4
Northern Sydney and Central Coast Area Health Service 48
Not applicableWithdrawnNCT04926168
What this trial is testing

6 Months Adjuvant Temozolomide (TMZ) vs No Adjuvant TMZ in Newly Diagnosed MGMT Methylated Glioblastoma (GBM)

Who this might be right for
MGMT-Methylated Glioblastoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Testing effectiveness (Phase 2)UnknownNCT01737346
What this trial is testing

Procarbazine and Lomustine in Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma Multiforme
Incheon St.Mary's Hospital 52
Early research (Phase 1)UnknownNCT03687034
What this trial is testing

The Safety and Pharmacokinetics of BRCX014 in Patients With Glioblastoma

Who this might be right for
Glioblastoma
Leaf Vertical Inc. 21
Early research (Phase 1)Ended earlyNCT01700569
What this trial is testing

Phase-1 Study of Folinic Acid to Modulate MGMT Gene in Glioblastoma

Who this might be right for
Grade IV AstrocytomaGlioblastoma
Institut Cancerologie de l'Ouest 24
Large-scale testing (Phase 3)Looking for participantsNCT06419946
What this trial is testing

Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma

Who this might be right for
Glioblastoma, IDH-wildtypeMGMT-Methylated Glioblastoma
Vastra Gotaland Region 200
Early research (Phase 1)Study completedNCT04842513
What this trial is testing

Multi Peptide Vaccination with XS15 in Addition to Standard Postoperative Radiation Therapy and Temozolomide Chemotherapy in Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma Multiforme of Brain
University Hospital Tuebingen 15
Large-scale testing (Phase 3)Active Not RecruitingNCT05095376
What this trial is testing

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Who this might be right for
GlioblastomaGliosarcoma
NRG Oncology 265
Early research (Phase 1)Study completedNCT06095375
What this trial is testing

Regorafenib With Temozolomide With or Without RT in MGMT-Methylated, IDH Wild-type GBM Patients

Who this might be right for
Glioblastoma, IDH-wildtypeMGMT-Methylated Glioblastoma
Istituto Oncologico Veneto IRCCS 21
Large-scale testing (Phase 3)Study completedNCT01149109
What this trial is testing

Efficacy and Safety Study of Lomustine/Temozolomide Combination Therapy vs. Standard Therapy for Glioblastoma Patients

Who this might be right for
Glioblastoma
University Hospital, Bonn 141
Large-scale testing (Phase 3)Looking for participantsNCT03970447
What this trial is testing

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Who this might be right for
Glioblastoma
Global Coalition for Adaptive Research 2,250
Testing effectiveness (Phase 2)Looking for participantsNCT06649851
What this trial is testing

G-CSF After Chemo-radiation in Patients With Glioblastoma

Who this might be right for
MGMT-Methylated GlioblastomaGlioblastoma (GBM)Newly Diagnosed Glioblastoma Multiforme
Massachusetts General Hospital 60
Large-scale testing (Phase 3)Study completedNCT00689221
What this trial is testing

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status

Who this might be right for
Glioblastoma
EMD Serono 545
Large-scale testing (Phase 3)Study completedNCT02667587
What this trial is testing

An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)

Who this might be right for
Brain Neoplasms
Bristol-Myers Squibb 716
Testing effectiveness (Phase 2)WithdrawnNCT04933942
What this trial is testing

Phase II Trial of Romiplostim for Thrombocytopenia Induced by Lomustine at First Progression of MGMT Promoter-meth Glioblastoma

Who this might be right for
First Progression of MGMT Promoter-methylated Glioblastoma
European Organisation for Research and Treatment of Cancer - EORTC
Testing effectiveness (Phase 2)Looking for participantsNCT06991101
What this trial is testing

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Who this might be right for
GlioblastomaBrain CancerGlioblastoma Multiforme+4 more
Baptist Health South Florida 190
Testing effectiveness (Phase 2)Looking for participantsNCT05432804
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent MGMT-Methylated Glioblastoma
National Cancer Institute (NCI) 97
Early research (Phase 1)Ended earlyNCT02576665
What this trial is testing

Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)

Who this might be right for
Colorectal CancerTriple Negative Breast CancerPancreatic Cancer+9 more
Tocagen Inc. 21
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