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Results for “MIBC”

60 trials

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Showing 20 of 60 results

Large-scale testing (Phase 3)Study completedNCT04209114
What this trial is testing

Nivolumab Plus Bempegaldesleukin (Bempeg/NKTR-214) vs Nivolumab Alone vs Standard of Care in Participants With Bladder Cancer That May Have Invaded The Muscle Wall of the Bladder and Who Cannot Get Cisplatin, A Type of Medicine Given To Treat Bladder Cancer

Who this might be right for
Bladder CancerBladder TumorMuscle-Invasive Bladder Cancer
Bristol-Myers Squibb 114
Not applicableLooking for participantsNCT06991868
What this trial is testing

Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD)

Who this might be right for
NMIBCMIBCUTUC
Peking University First Hospital 300
Early research (Phase 1)Active Not RecruitingNCT02546661
What this trial is testing

Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer

Who this might be right for
Muscle Invasive Bladder Cancer
AstraZeneca 117
Testing effectiveness (Phase 2)Looking for participantsNCT05706129
What this trial is testing

Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Clear Cell Renal Cell Cancer (ccRCC)Pancreatic Ductal Adenocarcinoma (PDAC)Colorectal Cancer (CRC)+6 more
ITM Oncologics GmbH 270
Large-scale testing (Phase 3)Active Not RecruitingNCT03732677
What this trial is testing

Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC

Who this might be right for
Muscle Invasive Bladder Cancer
AstraZeneca 1,063
Not applicableUnknownNCT05236218
What this trial is testing

To Better Understand the Most Important Factors for Patients When They Decide on the Type of Treatment They Receive for Muscle Invasive Bladder Cancer (MIBC).

Who this might be right for
Muscle Invasive Bladder CancerSurgerySexual Wellbeing+2 more
King's College London 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06623162
What this trial is testing

Sasanlimab As Maintenance Treatment Based on Clinical Response to Neoadjuvant Treatment in Molecularly Categorized Muscle Invasive Bladder Cancer Patients

Who this might be right for
MibcMuscle Invasive Bladder Cancer
Fundación de investigación HM 70
Testing effectiveness (Phase 2)Ended earlyNCT05041101
What this trial is testing

Grapiprant and Eribulin for the Treatment of Metastatic Inflammatory Breast Cancer

Who this might be right for
Breast Inflammatory CarcinomaRecurrent Breast Inflammatory CarcinomaStage IV Breast Inflammatory Carcinoma
M.D. Anderson Cancer Center 6
Testing effectiveness (Phase 2)Looking for participantsNCT06511648
What this trial is testing

Erdafitinib Monotherapy or in Combination With Cetrelimab in Muscle-invasive Bladder Cancer Patients With Fibroblast Growth Factor Receptor (FGFR ) Gene Alterations

Who this might be right for
Muscle-invasive Bladder Cancer
Spanish Oncology Genito-Urinary Group 90
Testing effectiveness (Phase 2)UnknownNCT04047693
What this trial is testing

Neoadjuvant Dose Dense MVAC in MIBC and Locally Advanced Urothelial Carcinoma

Who this might be right for
Muscle Invasive Bladder CancerUrothelial CarcinomaNeoadjuvant Chemotherapy
Pusan National University Yangsan Hospital 32
Not applicableWithdrawnNCT05860543
What this trial is testing

Clinical Performance Evaluation of the C2i Test

Who this might be right for
Muscle Invasive Bladder Cancer
University of Texas Southwestern Medical Center
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07279597
What this trial is testing

A Phase II Study of Toripalimab Plus RC48-ADC With Radiotherapy for Bladder Preservation in HER2-Positive Muscle-Invasive Bladder Cancer

Who this might be right for
Muscle-invasive Bladder Urothelial Carcinoma
Tongji Hospital 45
Testing effectiveness (Phase 2)Looking for participantsNCT06417190
What this trial is testing

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

Who this might be right for
Muscle-Invasive Bladder CarcinomaTumor
Leslie Ballas 20
Testing effectiveness (Phase 2)Ended earlyNCT03397394
What this trial is testing

Rucaparib in Patients With Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Bladder CancerUrothelial CarcinomaMetastatic Urothelial Carcinoma+5 more
pharmaand GmbH 97
Large-scale testing (Phase 3)Active Not RecruitingNCT03924856
What this trial is testing

Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

Who this might be right for
Bladder Cancer
Merck Sharp & Dohme LLC 907
Testing effectiveness (Phase 2)Looking for participantsNCT05072600
What this trial is testing

Pembrolizumab Monotherapy Following Tri-modality Treatment for Selected Patients With Muscle-invasive Bladder Cancer

Who this might be right for
Bladder CancerBladder NeoplasmsBladder Tumors+2 more
Peking University First Hospital 54
Not applicableStudy completedNCT06337591
What this trial is testing

Diagnostic Performance of the Vesical Imaging-Reporting and Data System (VI-RADS) in Detecting Muscle-invasive Bladder Tumour (MIBC) in Clinical Practice: Comparison With Transurethral Resection of Bladder Cancer (TURB) and Evaluation of Diagnostic Accuracy According to Tumour Location

Who this might be right for
Bladder Cancer
Istituto Nazionale di Ricovero e Cura per Anziani 20
Testing effectiveness (Phase 2)UnknownNCT04543110
What this trial is testing

Radiation and Durvalumab Immunotherapy As Neoadjuvant Treatment for MIBC

Who this might be right for
Bladder Cancer
Ottawa Hospital Research Institute 16
Not applicableActive Not RecruitingNCT03333356
What this trial is testing

Adjuvant Radiotherapy in Patients With Pathological High-risk Bladder Cancer (GETUG-AFU 30)

Who this might be right for
Patients With High-risk MIBC
UNICANCER 81
Testing effectiveness (Phase 2)UnknownNCT03993249
What this trial is testing

Nivolumab Plus Chemoradiotherapy in Patients With Muscle-invasive Bladder Cancer (MIBC) Not Undergoing Cystectomy

Who this might be right for
Bladder Cancer
Hellenic GenitoUrinary Cancer Group 78
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