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Results for “MPN (Myeloproliferative Neoplasms)”

97 trials

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Showing 20 of 97 results

Testing effectiveness (Phase 2)Looking for participantsNCT04996875
What this trial is testing

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Who this might be right for
Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc. 140
Not applicableNot Yet RecruitingNCT07384039
What this trial is testing

Exercise Training in Patients With Myeloproliferative Neoplasms

Who this might be right for
Myeloproliferative Neoplasms (MPN)
Hannover Medical School 80
Testing effectiveness (Phase 2)Study completedNCT04243122
What this trial is testing

Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients

Who this might be right for
Myeloproliferative Neoplasm (MPN)Essential Thrombocythemia (ET)JAK2 Mutation+3 more
Ottawa Hospital Research Institute 44
Testing effectiveness (Phase 2)Study completedNCT03011372
What this trial is testing

Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement - (FIGHT-203)

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 47
Testing effectiveness (Phase 2)Study completedNCT02125318
What this trial is testing

Anagrelide Controlled Release (GALE-401) in Patients With High Platelet Counts Due to Bone Marrow Disorders

Who this might be right for
ThrombocytosisMyeloproliferative Neoplasms
Galena Biopharma, Inc. 18
Testing effectiveness (Phase 2)Ended earlyNCT02711137
What this trial is testing

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors
Incyte Corporation 137
Not applicableActive Not RecruitingNCT07204366
What this trial is testing

Autoantibodies Against Type I Interferon in Patients Affected With Ph-negative Myeloproliferative Neoplasms (MPN-IFN Study)

Who this might be right for
Myeloproliferative DiseaseCOVID - 19
Fondazione IRCCS Policlinico San Matteo di Pavia 219
Early research (Phase 1)Looking for participantsNCT05549661
What this trial is testing

Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms

Who this might be right for
Recurrent Chronic Myelomonocytic LeukemiaRefractory Chronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified+3 more
Mayo Clinic 25
Not applicableStudy completedNCT04385160
What this trial is testing

Myeloproliferative Neoplasms (MPN) and COVID-19

Who this might be right for
Myeloproliferative NeoplasmCOVID
FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS 552
Testing effectiveness (Phase 2)Study completedNCT01606579
What this trial is testing

Safety and Efficacy Study of PRI-724 in Subjects With Advanced Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaChronic Myeloid Leukemia
Prism Pharma Co., Ltd. 49
Not applicableLooking for participantsNCT07143669
What this trial is testing

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

Who this might be right for
Clonal Mast Cell DiseaseKIT D816V MutationSuspected KITD816V Mutated Clonal Mast Cell Disease
Blueprint Medicines Corporation 450
Not applicableStudy completedNCT02775383
What this trial is testing

The National Myelodysplastic Syndromes (MDS) Study

Who this might be right for
Myelodysplastic Syndromes (MDS)
National Heart, Lung, and Blood Institute (NHLBI) 2,115
Testing effectiveness (Phase 2)Study completedNCT02076191
What this trial is testing

Study of Combination Ruxolitinib and Decitabine Treatment for Accelerated Phase MPN or Post-MPN AML

Who this might be right for
Myeloproliferative Neoplasms
John Mascarenhas 49
Not applicableStudy completedNCT02252159
What this trial is testing

Prospective Observational Study Of Patients With Polycythemia Vera In US Clinical Practices (REVEAL)

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 2,544
Testing effectiveness (Phase 2)Study completedNCT01633372
What this trial is testing

An Open Label Study of Itacitinib Administered Orally in Patients With Myelofibrosis

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 87
Early research (Phase 1)Ended earlyNCT04637009
What this trial is testing

TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMyeloproliferative NeoplasmMyelodysplastic/Myeloproliferative Neoplasm
Astex Pharmaceuticals, Inc. 20
Early research (Phase 1)Study completedNCT02493530
What this trial is testing

TGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea

Who this might be right for
MyelofibrosisPolycythemia Vera
Vanderbilt-Ingram Cancer Center 60
Early research (Phase 1)Study completedNCT01393509
What this trial is testing

The First-in-human Phase I Trial of PU-H71 in Patients With Advanced Malignancies

Who this might be right for
Metastatic Solid TumorLymphomaMyeloproliferative Neoplasms (MPN)
Memorial Sloan Kettering Cancer Center 47
Early research (Phase 1)Ended earlyNCT05524857
What this trial is testing

Combination of Fedratinib and Decitabine for Myeloproliferative Neoplasms (MPN)- Accelerated Phase (AP)/Blast Phase (BP)

Who this might be right for
Myeloproliferative Neoplasm
Joseph Jurcic 2
Early research (Phase 1)Looking for participantsNCT04771572
What this trial is testing

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Who this might be right for
Non Hodgkin LymphomaRichter TransformationMultiple Myeloma+10 more
Newave Pharmaceutical Inc 100
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