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Results for “MPN (Myeloproliferative Neoplasms)”

99 trials

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Showing 20 of 99 results

Testing effectiveness (Phase 2)Looking for participantsNCT04996875
What this trial is testing

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Who this might be right for
Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc. 140
Testing effectiveness (Phase 2)Ended earlyNCT04113616
What this trial is testing

An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 When Administered Alone and in Combination With Low-Dose Cytarabine (LDAC) or Decitabine in Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
Relapsed or Refractory Acute Myeloid Leukemia (AML)Acute Myeloid Leukemia (AML), Secondary to Myeloproliferative Neoplasms (MPN)
Kartos Therapeutics, Inc. 70
Not applicableNot Yet RecruitingNCT06615414
What this trial is testing

Cardiovascular Manifestations in Ph-negative MPN

Who this might be right for
Philadelphia Negative Myeloproliferative Neoplasms
Assiut University 80
Large-scale testing (Phase 3)Study completedNCT03952039
What this trial is testing

An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib

Who this might be right for
Primary MyelofibrosisPost-Polycythemia VeraMyelofibrosis
Celgene 202
Not applicableEnded earlyNCT01688011
What this trial is testing

Connect® Myeloid Disease Registry

Who this might be right for
Primary MyelofibrosisMyelodysplastic SyndromesLeukemia, Myeloid, Acute
Celgene 2,013
Early research (Phase 1)Active Not RecruitingNCT03613532
What this trial is testing

Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Chronic Myelomonocytic Leukemia (CMML)+2 more
Jacqueline Garcia, MD 102
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07468916
What this trial is testing

Ropeginterferon Alfa-2b for the Treatment of Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes and Chronic Myelomonocytic Leukemia

Who this might be right for
Atypical Chronic Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm+2 more
Jonsson Comprehensive Cancer Center 35
Large-scale testing (Phase 3)Study completedNCT01178281
What this trial is testing

Study of Pomalidomide in Persons With Myeloproliferative-Neoplasm-Associated Myelofibrosis and RBC-Transfusion-Dependence

Who this might be right for
Primary MyelofibrosisMPN-associated Myelofibrosis
Celgene 267
Not applicableLooking for participantsNCT06480591
What this trial is testing

Evaluation of the Pathobiology of CALR-mutated MPN Cells

Who this might be right for
Myeloproliferative Neoplasm
Wake Forest University Health Sciences 35
Testing effectiveness (Phase 2)Looking for participantsNCT04771130
What this trial is testing

BGB-11417 in Participants With Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Neoplasm
BeiGene 260
Early research (Phase 1)Study completedNCT02493530
What this trial is testing

TGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea

Who this might be right for
MyelofibrosisPolycythemia Vera
Vanderbilt-Ingram Cancer Center 60
Not applicableStudy completedNCT02953704
What this trial is testing

Myelofibrosis and Essential Thrombocythemia Observational Study (MOST)

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 1,469
Not applicableStudy completedNCT02252159
What this trial is testing

Prospective Observational Study Of Patients With Polycythemia Vera In US Clinical Practices (REVEAL)

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 2,544
Early research (Phase 1)Looking for participantsNCT04771572
What this trial is testing

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Who this might be right for
Non Hodgkin LymphomaRichter TransformationMultiple Myeloma+10 more
Newave Pharmaceutical Inc 100
Testing effectiveness (Phase 2)Looking for participantsNCT05732961
What this trial is testing

Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms

Who this might be right for
Myelodysplastic SyndromesMyeloproliferative NeoplasmAnemia
H. Lee Moffitt Cancer Center and Research Institute 70
Early research (Phase 1)WithdrawnNCT02564536
What this trial is testing

Pacritinib in Combination With Low Dose Decitabine in Intermediate-High Risk Myelofibrosis or Myeloproliferative Neoplasm (MPN)/Myelodysplastic Syndrome (MDS)

Who this might be right for
Chronic Myelomonocytic LeukemiaJuvenile Myelomonocytic LeukemiaAtypical Chronic Myeloid Leukemia+3 more
Washington University School of Medicine
Early research (Phase 1)Looking for participantsNCT05025488
What this trial is testing

Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm

Who this might be right for
MyelofibrosisEssential ThrombocythemiaMPN
Marina Kremyanskaya 10
Not applicableLooking for participantsNCT01351545
What this trial is testing

Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Who this might be right for
Hematologic MalignanciesInherited Disorders of MetabolismInherited Abnormalities of Platelets+14 more
Center for International Blood and Marrow Transplant Research 99,999
Not applicableStudy completedNCT04385160
What this trial is testing

Myeloproliferative Neoplasms (MPN) and COVID-19

Who this might be right for
Myeloproliferative NeoplasmCOVID
FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS 552
Testing effectiveness (Phase 2)Active Not RecruitingNCT05482971
What this trial is testing

A Single-arm, Multicenter Study to Assess the Efficacy, Safety, and Tolerability of P1101 in Adults With ET

Who this might be right for
Essential Thrombocythemia
PharmaEssentia 91
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