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Results for “MPN (Myeloproliferative Neoplasms)”

108 trials

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Showing 20 of 108 results

Testing effectiveness (Phase 2)Study completedNCT02125318
What this trial is testing

Anagrelide Controlled Release (GALE-401) in Patients With High Platelet Counts Due to Bone Marrow Disorders

Who this might be right for
ThrombocytosisMyeloproliferative Neoplasms
Galena Biopharma, Inc. 18
Not applicableActive Not RecruitingNCT04378855
What this trial is testing

Patient-Reported Outcomes in PHiladelphia-nEgative Cytogenetic mYeloproliferative Neoplasms (PROPHECY).

Who this might be right for
Myeloproliferative Neoplasm
Gruppo Italiano Malattie EMatologiche dell'Adulto 572
Large-scale testing (Phase 3)UnknownNCT02611973
What this trial is testing

Hydroxyurea Versus Aspirin and Hydroxyurea in Essential Thrombocythemia

Who this might be right for
MPNEssential Thrombocythemia
Assistance Publique - Hôpitaux de Paris 2,250
Testing effectiveness (Phase 2)Ended earlyNCT04639024
What this trial is testing

ADCT-301 in Patients With R/R AML, MDS, or MDS/MPN

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Myeloproliferative Neoplasm (MDS/MPN)
Gwynn Long, M.D. 3
Not applicableStudy completedNCT01816256
What this trial is testing

Screening for Asymptomatic Portal Vein Thrombosis and Portal Hypertension in Patients With Philadelphia Negative Myeloproliferative Neoplasms

Who this might be right for
Myeloproliferative Neoplasms (MPN)Polycythemia Vera (PV)Essential Thrombocythemia (ET)+1 more
University Health Network, Toronto 102
Testing effectiveness (Phase 2)Ended earlyNCT04103645
What this trial is testing

Intra-patient Dose Escalation Study to Investigate Safety and Feasibility of Vactosertib in Treating Anemic MPN Patients

Who this might be right for
Myeloproliferative Neoplasm
Weill Medical College of Cornell University 2
Testing effectiveness (Phase 2)Looking for participantsNCT06892223
What this trial is testing

Anti-NKG2A Monoclonal Antibody for AML or MDS Patients Undergoing Haploidentical Transplantation

Who this might be right for
Acute Myeloid LeukaemiaMDS (Myelodysplastic Syndrome)MPN (Myeloproliferative Neoplasms)
Istituto Clinico Humanitas 42
Large-scale testing (Phase 3)Study completedNCT03952039
What this trial is testing

An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib

Who this might be right for
Primary MyelofibrosisPost-Polycythemia VeraMyelofibrosis
Celgene 202
Testing effectiveness (Phase 2)Active Not RecruitingNCT05732961
What this trial is testing

Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms

Who this might be right for
Myelodysplastic SyndromesMyeloproliferative NeoplasmAnemia
H. Lee Moffitt Cancer Center and Research Institute 6
Testing effectiveness (Phase 2)WithdrawnNCT05612633
What this trial is testing

Zelavespib (PU-H71) in Subjects With AP-MPN or BP-MPN

Who this might be right for
Accelerated Phase MPNBlast Phase MPN
Samus Therapeutics, Inc.
Early research (Phase 1)Looking for participantsNCT07469891
What this trial is testing

PRT12396 in Participants With Select Myeloproliferative Neoplasms

Who this might be right for
Polycythemia Vera (PV)Myelofibrosis (MF)Myeloproliferative Neoplasms (MPNs)+3 more
Prelude Therapeutics Incorporated 100
Not applicableStudy completedNCT03907774
What this trial is testing

MPN Podcast Pilot Study

Who this might be right for
Myeloproliferative Neoplasm, Unclassifiable
Arizona State University 39
Not applicableStudy completedNCT02775383
What this trial is testing

The National Myelodysplastic Syndromes (MDS) Study

Who this might be right for
Myelodysplastic Syndromes (MDS)
National Heart, Lung, and Blood Institute (NHLBI) 2,115
Early research (Phase 1)Ended earlyNCT01066468
What this trial is testing

Glivec/Gleevec Pediatric (Age 1 to Less Than 4) PK Study in CML, Ph+ ALL Patients and Other Glivec/Gleevec® Indicated Hematological Disorders.

Who this might be right for
Chronic Myeloid Leukemia (CML)Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)Other Glivec/Gleevec Indicated Hematological Disorders (HES, CEL, MDS/ MPN)
Novartis Pharmaceuticals 3
Testing effectiveness (Phase 2)WithdrawnNCT05927012
What this trial is testing

Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (Iron Deficiency Anemia).

Who this might be right for
Iron Deficiency Anemia
Keros Therapeutics, Inc.
Large-scale testing (Phase 3)Looking for participantsNCT06740916
What this trial is testing

Long-term Efficacy of Once Daily Versus Twice Daily Aspirin in High-risk MPN Patients With Aspirin Resistance

Who this might be right for
Myeloproliferative Neoplasms (MPN)
Siriraj Hospital 240
Testing effectiveness (Phase 2)Study completedNCT03238248
What this trial is testing

Pevonedistat and Azacitidine in MDS or MDS/MPN Patients Who Fail Primary Therapy With DNA Methyl Transferase Inhibitors

Who this might be right for
Myelodysplastic SyndromesMyeloproliferative Neoplasm
Vanderbilt-Ingram Cancer Center 71
Not applicableNot Yet RecruitingNCT07832513
What this trial is testing

Study of Pregnancy in Patients With Myeloproliferative Neoplasms

Who this might be right for
Myeloproliferative Neoplasm (MPN)Pregnancy
University Health Network, Toronto 30
Not applicableLooking for participantsNCT05882773
What this trial is testing

Asian Myeloproliferative Neoplasm (MPN) Registry

Who this might be right for
Myeloproliferative NeoplasmPolycythemia VeraEssential Thrombocythemia+5 more
The University of Hong Kong 1,000
Testing effectiveness (Phase 2)Looking for participantsNCT05123365
What this trial is testing

An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms

Who this might be right for
Myeloproliferative NeoplasmMPNEssential Thrombocythemia+2 more
University of California, Irvine 27
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