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Results for “MRD-positive”

86 trials

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Showing 20 of 86 results

Large-scale testing (Phase 3)UnknownNCT03624530
What this trial is testing

Effect of Prophylactic TKI Therapy Post-transplants on Ph+ ALL Undergoing Allo-HSCT With MRD Positive Pre-transplants

Who this might be right for
Philadelphia Chromosome Positive Acute Lymphocytic LeukemiaTyrosine Kinase InhibitorMinimal Residual Disease+1 more
Nanfang Hospital, Southern Medical University 82
Testing effectiveness (Phase 2)Looking for participantsNCT05846737
What this trial is testing

BCMA CAR-T Cell Therapy in High-risk NDMM Patients With Positive MRD After First-line ASCT

Who this might be right for
Multiple Myeloma
Institute of Hematology & Blood Diseases Hospital, China 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT04086264
What this trial is testing

IMGN632 as Monotherapy or With Venetoclax and/or Azacitidine for Participants With CD123-Positive Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
AbbVie 218
Testing effectiveness (Phase 2)Ended earlyNCT03951961
What this trial is testing

Midostaurin in MRD (Minimal Residual Disease) Positive Acute Myeloid Leukemia After Allogeneic Stem Cell Transplantation

Who this might be right for
Acute Myeloid Leukemia, Adult
University of Jena 1
Early research (Phase 1)Study completedNCT03919526
What this trial is testing

Anti-CD19/CD22 Bispecific Chimeric Antigen Receptor（CAR)-T Cell Therapy for Measurable Residual Disease(MRD) Positive ALL

Who this might be right for
MRD-positiveAcute Lymphoblastic Leukemia
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 19
Testing effectiveness (Phase 2)Study completedNCT02067143
What this trial is testing

MRD/Risk-oriented Therapy of Adult Ph- ALL Including Pegylated Asparaginase and Lineage-targeted Methotrexate

Who this might be right for
Untreated Philadelphia Positive Acute Lymphoblastic LeukemiaDe NovoSecondary+1 more
Gruppo Italiano Malattie EMatologiche dell'Adulto 204
Testing effectiveness (Phase 2)Looking for participantsNCT06718244
What this trial is testing

Inaticabtagene Autoleucel (Inati-cel; CNCT19) Treatment for MRD-Positive B-ALL Patients in CR1

Who this might be right for
Acute Lymphoblastic Leukemia
Ruijin Hospital 20
Not applicableLooking for participantsNCT06479460
What this trial is testing

Clinical Application of ctDNA Dynamic Monitoring in Neoadjuvant Therapy for HER2-positive Breast Cancer Patients

Who this might be right for
Breast CancerNeoadjuvantHER2-positive Breast Cancer+1 more
The First Affiliated Hospital with Nanjing Medical University 50
Early research (Phase 1)Active Not RecruitingNCT03927261
What this trial is testing

PRGN-3006 Adoptive Cellular Therapy for CD33-Positive Relapsed or Refractory AML, MRD Positive AML or Higher Risk MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Precigen, Inc 88
Very early researchLooking for participantsNCT07126782
What this trial is testing

The Efficacy and Safety Assessment of Allogeneic γδ T Cells in Patients With MRD-positive AML After Allo-HSCT

Who this might be right for
AML (Acute Myelogenous Leukemia)AML
Institute of Hematology & Blood Diseases Hospital, China 10
Post-approval studies (Phase 4)Looking for participantsNCT06561620
What this trial is testing

Befotertinib Adjuvant Therapy in Stage IA2-IB NSCLC Patients

Who this might be right for
3-year Disease-free Survival
Fudan University 592
Testing effectiveness (Phase 2)Active Not RecruitingNCT04475731
What this trial is testing

Ponatinib in Adult Ph+ ALL Patients With MRD Positivity or Hematological Relapse

Who this might be right for
Philadelphia-Positive ALLAcute Lymphoblastic Leukemia, in Relapse
Gruppo Italiano Malattie EMatologiche dell'Adulto 67
Not applicableLooking for participantsNCT07006012
What this trial is testing

RGL-305+ Lymphoma + Exploratory Clinical Study

Who this might be right for
Lymphoma Patients With Complete Response (CR) or Partial Response (PR) After Standard Treatment Had a Positive Minimal Residual Lesion (MRD)
Fudan University 12
Testing effectiveness (Phase 2)Ended earlyNCT03523429
What this trial is testing

PETHEMA-BLIN-01/PET069014 (BLIN-01)

Who this might be right for
Philadelphia Chromosome-negative or BCR-ABL-negative, CD19-positive ALL
PETHEMA Foundation 11
Testing effectiveness (Phase 2)Looking for participantsNCT06517212
What this trial is testing

Tirzepatide Weight Loss for MRD+ Early Breast Cancer

Who this might be right for
Breast CancerBreast NeoplasmsBreast Cancers
Baylor Research Institute 48
Testing effectiveness (Phase 2)Study completedNCT02722668
What this trial is testing

UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

Who this might be right for
Acute LeukemiaAcute Myeloid LeukemiaAcute Lymphoblastic Leukemia/Lymphoma+22 more
Masonic Cancer Center, University of Minnesota 15
Not applicableLooking for participantsNCT07131059
What this trial is testing

MRD-positive AML Clinical Study

Who this might be right for
AML, Adult
Institute of Hematology & Blood Diseases Hospital, China 120
Not applicableStudy completedNCT05440409
What this trial is testing

CAR-Multicenter Analysis (CAR-MA): Retrospective Study to Characterize CAR T-cell Outcomes and Related Toxicities in Children and Young Adults With B-ALL

Who this might be right for
Leukemia, Acute LymphoblasticLymphoblastic Leukemia, Acute, Childhood
National Cancer Institute (NCI) 57
Testing effectiveness (Phase 2)Ended earlyNCT01158885
What this trial is testing

Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia

Who this might be right for
Minimal Residual DiseaseLeukemia, Lymphoblastic, AcuteLeukemia, Myelogenous, Acute
Therapeutic Advances in Childhood Leukemia Consortium 2
Early research (Phase 1)Looking for participantsNCT06752785
What this trial is testing

CD19/CD22 CAR-T Cell Therapy in MRD-Positive B-lineage Acute Lymphoblastic Leukemia in Children.

Who this might be right for
Acute Lymphoblastic Leukemia
Guangzhou Women and Children's Medical Center 10
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