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Results for “MSI”

300 trials

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Showing 20 of 300 results

Testing effectiveness (Phase 2)Ended earlyNCT03431311
What this trial is testing

T Cell Receptor Based Therapy of Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Oslo University Hospital 1
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07266025
What this trial is testing

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma：A Randomized, Non-comparative Phase 2 Study

Who this might be right for
Gastric AdenocarcinomaGastroesophageal AdenocarcinomaMismatch Repair Deficient or MSI-High Solid Tumors+1 more
Shanghai Zhongshan Hospital 30
Early research (Phase 1)Study completedNCT02482168
What this trial is testing

Study of the CD40 Agonistic Monoclonal Antibody APX005M

Who this might be right for
CancerNSCLCMelanoma+3 more
Apexigen America, Inc. 43
Testing effectiveness (Phase 2)Looking for participantsNCT05731726
What this trial is testing

Serplulimab Combined with CAPEOX + Celecoxib As Neoadjuvant Treatment for Locally Advanced Rectal Cancer

Who this might be right for
PMMRMSSMSI-L+1 more
Zhejiang University 50
Testing effectiveness (Phase 2)Looking for participantsNCT07213609
What this trial is testing

Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

Who this might be right for
Neoplasms, ColorectalNeoplasms
GlaxoSmithKline 47
Testing effectiveness (Phase 2)Active Not RecruitingNCT03104439
What this trial is testing

Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer

Who this might be right for
Microsatellite Stable Colorectal CancerPancreatic CancerMSI High Colorectal Cancer
Massachusetts General Hospital 84
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07013851
What this trial is testing

Clinical Trial to Assess the Efficacy of Dostarlimab as Neoadjuvant Therapy in Patients With MMRd/MSI-H Stage II-III Endometrial Cancer

Who this might be right for
MMRd/MSI-H Stage II-III Endometrial Cancer
Grupo Español de Investigación en Cáncer de Ovario 25
Testing effectiveness (Phase 2)UnknownNCT03544723
What this trial is testing

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.

Who this might be right for
Solid TumorLymphoma
MultiVir, Inc. 40
Not applicableStudy completedNCT06717763
What this trial is testing

Surgery Following Immune Checkpoint Inhibitions for Controlled Disease in Recurrent or Metastatic dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal Cancer
Sun Yat-sen University 40
Testing effectiveness (Phase 2)WithdrawnNCT06331598
What this trial is testing

Adjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors with Resectable Disease with Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI-H)

Who this might be right for
Solid Tumors
Hoffmann-La Roche
Not applicableActive Not RecruitingNCT06642506
What this trial is testing

Oncometabolome and MALDI-MSI in Upper GI Carcinomas - Chemosensitivity in Esophageal Carcinoma

Who this might be right for
Esophagus AdenocarcinomaEsophagus CancerMetabolome+5 more
Ludwig-Maximilians - University of Munich 20
Not applicableStudy completedNCT05871567
What this trial is testing

Predictive Value of DNA Mismatch Repair System in Colorectal Cancers

Who this might be right for
MSI-H Colorectal Cancer
University of Campania Luigi Vanvitelli 403
Not applicableWithdrawnNCT01930994
What this trial is testing

Kenya Sino-implant (II) PK Study

Who this might be right for
Contraception
FHI 360
Early research (Phase 1)Study completedNCT03517488
What this trial is testing

XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Who this might be right for
MelanomaBreast CarcinomaHepatocellular Carcinoma+25 more
Xencor, Inc. 150
Testing effectiveness (Phase 2)WithdrawnNCT06365970
What this trial is testing

Niraparib and Dostarlimab for Patients With MMR-D/MSI-H Colorectal Cancers

Who this might be right for
MMR-D/MSI-H Colorectal Cancers
Ibrahim Halil Sahin
Not applicableNot Yet RecruitingNCT07274657
What this trial is testing

Superb Microvascular Imaging (SMI) and Two-Dimensional Endoscopic Ultrasound Guided Shear Wave Elastography (2D-SWE-EUS) in Differential Diagnosis of Pancreatic Adenocarcinoma (PA) From Other Pancreatic Solid Lesions (PSLs) and Pancreatic neuroendocrinE Tumors (pNETs) Malignancy

Who this might be right for
Pancreas Adenocarcinoma (MSI-H)Pancreatic Neuroendocrine Tumors (pNET)
GCS Ramsay Santé pour l'Enseignement et la Recherche 150
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07133750
What this trial is testing

PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer

Who this might be right for
CRC (Colorectal Cancer)
Biotheus Inc. 40
Early research (Phase 1)Active Not RecruitingNCT05544929
What this trial is testing

Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

Who this might be right for
Carcinoma, Non-Small-Cell LungCutaneous MelanomaCarcinoma, Renal Cell+9 more
Novartis Pharmaceuticals 126
Testing effectiveness (Phase 2)Active Not RecruitingNCT04715633
What this trial is testing

PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability High
Sun Yat-sen University 53
Testing effectiveness (Phase 2)Looking for participantsNCT06898450
What this trial is testing

Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

Who this might be right for
Advanced Solid Tumors CancerMSI-H Cancer
Nimbus Wadjet, Inc. 134
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