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Results for “MSI-H/dMMR Gastric Cancer”

27 trials

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Showing 20 of 27 results

Testing effectiveness (Phase 2)Looking for participantsNCT05769725
What this trial is testing

Evaluate Serplulimab in Combination With Docetaxel +S-1 VS. Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage IIIc Gastric Cancer

Who this might be right for
Serplulimab,Gastric Cancer, Adjuvant Therapy
RenJi Hospital 70
Large-scale testing (Phase 3)Looking for participantsNCT06346197
What this trial is testing

Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas

Who this might be right for
Gastric CancerMSI-HMetastatic Cancer+1 more
Centre Leon Berard 132
Testing effectiveness (Phase 2)Active Not RecruitingNCT06116136
What this trial is testing

Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers.

Who this might be right for
MSI-H/dMMR Gastroesophageal-junction CancerMSI-H/dMMR Gastric Cancer
Servier Bio-Innovation LLC 38
Testing effectiveness (Phase 2)Active Not RecruitingNCT04556253
What this trial is testing

AK104 in Locally Advanced MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer

Who this might be right for
MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer
Peking University 47
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06426654
What this trial is testing

Sintilimab Combined With LDRT for Neoadjuvant Treatment of Locally Advanced dMMR/MSI-H Gastric Cancer

Who this might be right for
Gastric Cancer
West China Hospital 45
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07262619
What this trial is testing

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

Who this might be right for
Advanced Solid TumorsMSI-H or dMMR Advanced Solid TumorsMSI-H/dMMR Gastric Cancer+4 more
Eikon Therapeutics 160
Testing effectiveness (Phase 2)Looking for participantsNCT06580574
What this trial is testing

Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers

Who this might be right for
Gastric CancerColon CancerMSI-H+1 more
Peking University 38
Testing effectiveness (Phase 2)Active Not RecruitingNCT05836584
What this trial is testing

Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer

Who this might be right for
Clinical Stage I Gastric Cancer AJCC v8Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage II Gastric Cancer AJCC v8+7 more
National Cancer Institute (NCI) 240
Testing effectiveness (Phase 2)Looking for participantsNCT06047379
What this trial is testing

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Who this might be right for
Diffuse Astrocytoma, IDH-MutantGlioblastoma, IDH-wildtypeBrain Metastases, Adult+18 more
Neonc Technologies, Inc. 134
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07266025
What this trial is testing

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma：A Randomized, Non-comparative Phase 2 Study

Who this might be right for
Gastric AdenocarcinomaGastroesophageal AdenocarcinomaMismatch Repair Deficient or MSI-High Solid Tumors+1 more
Shanghai Zhongshan Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT06250036
What this trial is testing

Zimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer

Who this might be right for
Locally Advanced Gastric AdenocarcinomaMSI-H/dMMR Gastric CancerMSI-H/dMMR Gastroesophageal-junction Cancer
Royal Marsden NHS Foundation Trust 50
Early research (Phase 1)Ended earlyNCT03407976
What this trial is testing

Apatinib With Pembrolizumab in Previously Treated Advanced Malignancies

Who this might be right for
Advanced MalignanciesUrothelial CarcinomaMSI-H or dMMR Solid Tumors+1 more
University of Utah 5
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07259473
What this trial is testing

Factors Influencing Immunotherapy Response in dMMR/MSI-H Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric / Gastroesophageal Junction AdenocarcinomaMismatch Repair Deficient or MSI-High Solid TumorsImmunotherapy
Shanghai Zhongshan Hospital 15
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07127822
What this trial is testing

Assessing Iparomlimab and Tuvonralimab in Recurrent or Metastatic MSI-H/dMMR Gastric Cancer

Who this might be right for
Gastric / Gastroesophageal Junction AdenocarcinomaMSI-H Cancer
Peking University 106
Testing effectiveness (Phase 2)Looking for participantsNCT06059495
What this trial is testing

Watch-and-Wait Approach With Dostarlimab in Localized dMMR/MSI-H Gastric Cancer: GERCOR Phase II Study

Who this might be right for
Adenocarcinoma - GEJGastric Adenocarcinoma
GERCOR - Multidisciplinary Oncology Cooperative Group 59
Testing effectiveness (Phase 2)UnknownNCT04152889
What this trial is testing

Evaluate Camrelizumab in Combination With Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage III Gastric Cancer

Who this might be right for
Gastric Cancer Stage III
RenJi Hospital 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT03228667
What this trial is testing

QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors

Who this might be right for
Non-Small Cell Lung CancerSmall Cell Lung CancerUrothelial Carcinoma+10 more
ImmunityBio, Inc. 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT04041310
What this trial is testing

Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors

Who this might be right for
Solid Tumor, Adult
Nouscom SRL 115
Testing effectiveness (Phase 2)UnknownNCT05994456
What this trial is testing

Neoadjuvant Toripalimab for dMMR/MSI-H Gastric Cancer

Who this might be right for
Gastric or Gastroesophageal Junction Adenocarcinoma
Sun Yat-sen University 24
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