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Results for “MSS”

291 trials

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Showing 20 of 291 results

Large-scale testing (Phase 3)Looking for participantsNCT06791512
What this trial is testing

MFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC

Who this might be right for
Colorectal Cancer (CRC)pMMR/MSS Adenocarcinoma of the Colon or Rectum
Jun Huang 166
Early research (Phase 1)Active Not RecruitingNCT02521844
What this trial is testing

Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumours

Who this might be right for
Solid Tumors
EDDC (Experimental Drug Development Centre), A*STAR Research Entities 89
Early research (Phase 1)Looking for participantsNCT07321106
What this trial is testing

Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal Cancer (CRC)Colorectal (Colon or Rectal) Cancer+4 more
Cartography Biosciences 80
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06014944
What this trial is testing

Short-course Radiotherapy Combined With Furoquintinib and PD-1 Monoclonal Antibody

Who this might be right for
Rectal Cancer
Changhai Hospital 30
Large-scale testing (Phase 3)Looking for participantsNCT06507371
What this trial is testing

Node-sparing Short-Course Radiation Combined With CAPOX and Tislelizumab for MSS Rectal Cancer

Who this might be right for
Rectal Cancer
Sir Run Run Shaw Hospital 170
Testing effectiveness (Phase 2)UnknownNCT04724239
What this trial is testing

Sintilimab and Chidamide in Combination With or Without IBI305 in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

Who this might be right for
Advanced Microsatellite Stable Colorectal CancerMetastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 48
Testing effectiveness (Phase 2)Looking for participantsNCT05731726
What this trial is testing

Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer

Who this might be right for
pMMRMSSMSI-L+1 more
Zhejiang University 50
Testing effectiveness (Phase 2)Looking for participantsNCT06567782
What this trial is testing

Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer

Who this might be right for
Neoplasms, Colon
GlaxoSmithKline 120
Not applicableStudy completedNCT04312724
What this trial is testing

An Investigation Into a New Manufacture Technique of Trans-femoral Sockets

Who this might be right for
Amputation
Össur Iceland ehf 47
Testing effectiveness (Phase 2)Looking for participantsNCT04109755
What this trial is testing

Neo-adjuvant Pembrolizumab and Radiotherapy in Localised MSS Rectal Cancer

Who this might be right for
Rectum CancerRectal Cancer
University Hospital, Geneva 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06835179
What this trial is testing

SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer.

Who this might be right for
Unresectable Metastatic Colorectal CancerMicrosatellite Stable (MSS) Colorectal Cancer (CRC)RAS-mutant Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 28
Very early researchLooking for participantsNCT07328087
What this trial is testing

COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColorectal Cancer Stage IIIColorectal Cancer Stage IV
Biogenea Pharmaceuticals Ltd. 12
Early research (Phase 1)Looking for participantsNCT07510308
What this trial is testing

Clinical Study of MSH2-/- Tumor Cell Vaccines for Advanced pMMR Colorectal Cancer Patients

Who this might be right for
pMMR/MSS Advanced Colorectal Cancer
West China Hospital 9
Testing effectiveness (Phase 2)Looking for participantsNCT07448142
What this trial is testing

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer (CRC)
Sun Yat-sen University 50
Testing effectiveness (Phase 2)UnknownNCT04527068
What this trial is testing

QL1101 in Combination With JS001 in Patients With pMMR/MSS Refractory Metastatic Colorectal Cancer

Who this might be right for
Refractory Metastatic Colorectal CancerpMMRMSS
Second Affiliated Hospital, School of Medicine, Zhejiang University 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07394192
What this trial is testing

Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer

Who this might be right for
Rectal CancerRadiotherapyPD-1 Inhibitor
Peking University Cancer Hospital & Institute 44
Testing effectiveness (Phase 2)Active Not RecruitingNCT03104439
What this trial is testing

Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer

Who this might be right for
Microsatellite Stable Colorectal CancerPancreatic CancerMSI High Colorectal Cancer
Massachusetts General Hospital 84
Testing effectiveness (Phase 2)Looking for participantsNCT06830239
What this trial is testing

Phase II Study of Neoadjuvant Dostarlimab in Patients With Untreated T3-4N0-2 or Stage III pMMR/MSS Resectable Colon Cancer

Who this might be right for
Colon Cancer Stage III
Universitaire Ziekenhuizen KU Leuven 10
Testing effectiveness (Phase 2)Study completedNCT03442569
What this trial is testing

PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC

Who this might be right for
Colon Cancer
UNC Lineberger Comprehensive Cancer Center 56
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