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Results for “MSS/pMMR”

135 trials

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Showing 20 of 135 results

Large-scale testing (Phase 3)Looking for participantsNCT05768503
What this trial is testing

Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC

Who this might be right for
Metastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 176
Testing effectiveness (Phase 2)UnknownNCT06304987
What this trial is testing

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Beijing Friendship Hospital 50
Testing effectiveness (Phase 2)UnknownNCT06239870
What this trial is testing

Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer

Who this might be right for
Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer
Yunnan Cancer Hospital 35
Testing effectiveness (Phase 2)UnknownNCT05160727
What this trial is testing

Radiotherapy Combined With Tislelizumab and Irinotecan in MSS/pMMR Recurrence and Metastatic Colorectal Cancer

Who this might be right for
Mismatch Repair-proficientColorectal Cancer MetastaticMicrosatellite Stable
Zhejiang Cancer Hospital 44
Testing effectiveness (Phase 2)Looking for participantsNCT07718490
What this trial is testing

Immunotheray Combined With Simvastatin and Target Therapy and Chemotharepy for Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 43
Testing effectiveness (Phase 2)Looking for participantsNCT07133750
What this trial is testing

PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer

Who this might be right for
CRC (Colorectal Cancer)
Biotheus Inc. 100
Testing effectiveness (Phase 2)UnknownNCT04659382
What this trial is testing

Study to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancerpMMRMSS+2 more
Federation Francophone de Cancerologie Digestive 52
Testing effectiveness (Phase 2)Looking for participantsNCT06864013
What this trial is testing

SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Zhejiang University 116
Testing effectiveness (Phase 2)Looking for participantsNCT06829355
What this trial is testing

"Thymalfasin Immunotherapy Study with Triple Regimen in Advanced MSS/pMMR Colorectal Cancer"

Who this might be right for
MCRC
Beijing Friendship Hospital 52
Testing effectiveness (Phase 2)Looking for participantsNCT06266832
What this trial is testing

The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma

Who this might be right for
Rectal Adenocarcinoma
Sir Run Run Shaw Hospital 30
Testing effectiveness (Phase 2)UnknownNCT05588297
What this trial is testing

Preoperative Nivolumab Plus Bevacizumab Combined With Chemotherapy Before Surgery in Patients With pMMR/MSS Colorectal Cancer Liver Metastases

Who this might be right for
Colorectal Cancer Liver Metastases
Shanghai Changzheng Hospital 12
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07381309
What this trial is testing

Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM

Who this might be right for
CRCLiver Metastasis Colon Cancer
Jun Huang 114
Testing effectiveness (Phase 2)Looking for participantsNCT06856837
What this trial is testing

- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases

Who this might be right for
Metastatic Colorectal Cancer
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 140
Testing effectiveness (Phase 2)UnknownNCT05970302
What this trial is testing

XELOX +Bev +Tislelizumab for First-line Treatment of MSS/pMMR RAS-mutated mCRC

Who this might be right for
TislelizumabBevacizumabOxaliplatin+5 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 52
Testing effectiveness (Phase 2)Looking for participantsNCT07550088
What this trial is testing

BAL/BOT/agenT-797 in pMMR CRC With Liver Metastases

Who this might be right for
Colorectal Cancer Metastatic
Darren Sigal, MD 17
Testing effectiveness (Phase 2)Looking for participantsNCT07005570
What this trial is testing

Short-course Radiotherapy Followed by Sequential Chemotherapy With or Without PD-1 Monoclonal Antibody and Bevacizumab as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer （SPARK）

Who this might be right for
pMMR/MSS Locally Advanced Rectal Cancer
Dechang Diao 86
Testing effectiveness (Phase 2)WithdrawnNCT05690035
What this trial is testing

Tislelizumab Combined With Fruquintinib for Metastatic pMMR/MSS Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancermCRC
Sun Yat-sen University
Testing effectiveness (Phase 2)UnknownNCT04483219
What this trial is testing

Tyrosine Kinase Inhibitor (TKI) + Anti-PD-1 Antibody in TKI-responded Microsatellite Stability/Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Adenocarcinoma.

Who this might be right for
MSSpMMRMetastatic Colorectal Adenocarcinoma
China Medical University, China 53
Testing effectiveness (Phase 2)Looking for participantsNCT06764680
What this trial is testing

Oral Chemotherapy, Targeted Therapy and Immunotherapy With/Without Radiotherapy as 3rd- or Later-line Therapy for Advanced MSS/pMMR Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticChemotherapyTargeted Therapy+2 more
Sun Yat-sen University 57
Testing effectiveness (Phase 2)UnknownNCT04527068
What this trial is testing

QL1101 in Combination With JS001 in Patients With pMMR/MSS Refractory Metastatic Colorectal Cancer

Who this might be right for
Refractory Metastatic Colorectal CancerpMMRMSS
Second Affiliated Hospital, Zhejiang University, School of Medicine 50
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