Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “MSS/pMMR”

115 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 115 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07527520
What this trial is testing

Neoadjuvant Moderately Hypofractionated Radiotherapy Combined With Chemotherapy and Immunotherapy for High-risk pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Multi-center Randomized Control Phase II Trial

Who this might be right for
Rectal CancerModerately Hypofractionated RadiotherapySerplulimab+1 more
Fudan University 165
Testing effectiveness (Phase 2)Looking for participantsNCT06884670
What this trial is testing

Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study

Who this might be right for
Rectal Cancer
The First Affiliated Hospital with Nanjing Medical University 130
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07224022
What this trial is testing

Cemiplimab With Fianlimab for Resectable Non-Metastatic Colon Cancer

Who this might be right for
Colon Cancer
John Strickler, M.D. 24
Testing effectiveness (Phase 2)WithdrawnNCT05582031
What this trial is testing

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

Who this might be right for
Anal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more
Translational Research in Oncology
Large-scale testing (Phase 3)Looking for participantsNCT06497985
What this trial is testing

Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients

Who this might be right for
Colorectal Cancer
Chipscreen Biosciences, Ltd. 430
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07175636
What this trial is testing

QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Mismatch Repair-Proficient (pMMR) Rectal CancerNon-metastatic Rectal Cancer
Sun Yat-sen University 66
Testing effectiveness (Phase 2)Looking for participantsNCT06830239
What this trial is testing

Phase II Study of Neoadjuvant Dostarlimab in Patients With Untreated T3-4N0-2 or Stage III pMMR/MSS Resectable Colon Cancer

Who this might be right for
Colon Cancer Stage III
Universitaire Ziekenhuizen KU Leuven 10
Early research (Phase 1)Not Yet RecruitingNCT07411781
What this trial is testing

PIN in Combination With Sintilimab in Previously Treated pMMR/MSS CRC With Hepatic Metastases

Who this might be right for
Colorectal CancerAdult
Chinese PLA General Hospital 25
Large-scale testing (Phase 3)Looking for participantsNCT06280495
What this trial is testing

Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients

Who this might be right for
Colorectal CancerLiver Metastases
Sun Yat-sen University 156
Not applicableStudy completedNCT06794099
What this trial is testing

Study on the Applicability of CCR Criteria in Rectal Cancer

Who this might be right for
PMMR/MSS Adenocarcinoma of the Colon or RectumNeoadjuvant ChemoradiotherapyImmunotherapy+1 more
Peking University Cancer Hospital & Institute 177
Testing effectiveness (Phase 2)Looking for participantsNCT06930118
What this trial is testing

The Aim of This Study is to Assess the Efficacy and Safety of Chidamide, Regorafenib in Combination With Iparomlimab and Tuvonralimab for the Treatment of Advanced Colorectal Cancer in Third-line Therapy and Subsequent Lines.

Who this might be right for
Advanced Colorectal Cancer in the Third-line Treatment and BeyondpMMR/MSS Advanced Colorectal Cancer
Shanghai Changzheng Hospital 60
Testing effectiveness (Phase 2)Ended earlyNCT06834399
What this trial is testing

TATE and KN046 in MCRC

Who this might be right for
Colorectal Cancer with Hepatic Metastases
Zhejiang Raygene Pharmaceuticals Co., Ltd 42
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07381400
What this trial is testing

Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally Advanced Rectal Cancer (FIRM02 Study)

Who this might be right for
Rectal Cancer
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 128
Testing effectiveness (Phase 2)Looking for participantsNCT06856837
What this trial is testing

- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases

Who this might be right for
Metastatic Colorectal Cancer
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 140
Testing effectiveness (Phase 2)Looking for participantsNCT06911684
What this trial is testing

Radiotherapy Plus Iparomlimab and Tuvonralimab (QL1706), Regorafenib, and CAPOX as Neoadjuvant Therapy for pMMR/MSS LARC.

Who this might be right for
Rectal Cancer Patients
Sun Yat-sen University 88
Testing effectiveness (Phase 2)Active Not RecruitingNCT06056804
What this trial is testing

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Beijing Friendship Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT06543836
What this trial is testing

CtDNA-guided Treatment of TKI Plus PD-1 Inhibitor for Advanced pMMR/MSS Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 68
Not applicableStudy completedNCT06011330
What this trial is testing

Fruquintinib Plus PD-1 in Refractory MSS Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hunan Cancer Hospital 70
Early research (Phase 1)Ended earlyNCT04108481
What this trial is testing

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColon CancerMetastatic Colorectal Cancer+7 more
University of Iowa 5
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07521605
What this trial is testing

Short-Course Radiotherapy, Nal-IRI, Capecitabine, and Camrelizumab for Locally Advanced MSS Rectal Cancer

Who this might be right for
Rectal Cancer Patients
Guangdong Provincial People's Hospital 44
Load More Results