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Results for “MSS/pMMR”

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Showing 20 of 0 results

Not applicableStudy completedNCT04482608
What this trial is testing

The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival

Who this might be right for
Colorectal Cancer MetastaticMismatch Repair DeficiencyMicrosatellite Instability High
Sun Yat-sen University 671
Not applicableStudy completedNCT06794099
What this trial is testing

Study on the Applicability of CCR Criteria in Rectal Cancer

Who this might be right for
PMMR/MSS Adenocarcinoma of the Colon or RectumNeoadjuvant ChemoradiotherapyImmunotherapy+1 more
Peking University Cancer Hospital & Institute 177
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07175636
What this trial is testing

QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Mismatch Repair-Proficient (pMMR) Rectal CancerNon-metastatic Rectal Cancer
Sun Yat-sen University 66
Not applicableActive Not RecruitingNCT06865521
What this trial is testing

Akkermansia Probiotics Plus Anti-PD-1 Monoclonal Antibody in MSS/pMMR Advanced Colorectal Cancer

Who this might be right for
Colo-rectal CancerPD-1 InhibitorAkkermansia Muciniphila
West China Hospital 22
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07021950
What this trial is testing

AK112 Plus FOLFIRI Versus Bevacizumab Plus FOLFIRI as Second-line Treatment of MSS/pMMR Metastatic Colorectal Cancer

Who this might be right for
Colorectal CancerIvonescimab
Sun Yat-sen University 130
Large-scale testing (Phase 3)Looking for participantsNCT06497985
What this trial is testing

Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients

Who this might be right for
Colorectal Cancer
Chipscreen Biosciences, Ltd. 430
Testing effectiveness (Phase 2)Looking for participantsNCT05669430
What this trial is testing

GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

Who this might be right for
Solid Tumor, AdultRefractory CancerEndometrial Carcinoma (EC)+4 more
GV20 Therapeutics 365
Testing effectiveness (Phase 2)Looking for participantsNCT07230639
What this trial is testing

Node-Sparing Hypofractionated Radiotherapy Plus Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Randomized, Phase II Trial

Who this might be right for
Neoadjuvant TherapiesImmune Checkpoint TherapyRadiotherapy
Sixth Affiliated Hospital, Sun Yat-sen University 52
Testing effectiveness (Phase 2)Looking for participantsNCT06923345
What this trial is testing

Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I)

Who this might be right for
Rectal CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 80
Testing effectiveness (Phase 2)Looking for participantsNCT07070518
What this trial is testing

Study of GV20-0251 in Participants With Solid Tumor Malignancies

Who this might be right for
Solid Tumor CancerAdult Refractory CancerEndometrial Carcinoma (EC)+6 more
GV20 Therapeutics 350
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07779694
What this trial is testing

16-Hour Fasting Plus Serplulimab and CAPEOX as Neoadjuvant Therapy in pMMR/MSS Advanced Mid-to-Low Rectal Cancer

Who this might be right for
pMMR/MSSLocally Advanced Rectal CarcinomaFasting, Intermittent
Zhejiang University 51
Testing effectiveness (Phase 2)Looking for participantsNCT06911684
What this trial is testing

Radiotherapy Plus Iparomlimab and Tuvonralimab (QL1706), Regorafenib, and CAPOX as Neoadjuvant Therapy for pMMR/MSS LARC.

Who this might be right for
Rectal Cancer Patients
Sun Yat-sen University 88
Testing effectiveness (Phase 2)Active Not RecruitingNCT06992024
What this trial is testing

Electroacupuncture Combined With Paclitaxel Protein-bound and PD-1 Antibody for Second-line Treatment of HER2 Negative, pMMR/MSS Advanced Gastric Cancer

Who this might be right for
Electroacupuncture Combined With Paclitaxel Protein-bound and PD-1 Antibody for Second-line Treatment of HER2 Negative, pMMR/MSS Advanced Gastric Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07591597
What this trial is testing

A Multicenter, Phase Ib/II Clinical Trial to Evaluate the Efficacy and Safety of Concurrent Combination Therapy of S-531011 Plus Fruquintinib or S-531011 Plus Fruquintinib Plus Pembrolizumab in Patients With MSS/pMMR Colorectal Cancer

Who this might be right for
Metastatic Colorectal NeoplasmsMicrosatellite Stable / Proficient Mismatch Repair Colorectal Cancer
National Cancer Center Hospital East 68
Large-scale testing (Phase 3)Looking for participantsNCT06958432
What this trial is testing

Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)

Who this might be right for
Rectal CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 430
Testing effectiveness (Phase 2)UnknownNCT04989855
What this trial is testing

Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score

Who this might be right for
Locally Advanced Rectal Cancer
Sun Yat-sen University 48
Large-scale testing (Phase 3)Not Yet RecruitingNCT06832917
What this trial is testing

Short-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III)

Who this might be right for
Rectal Cancer
Wan He 238
Testing effectiveness (Phase 2)WithdrawnNCT07137390
What this trial is testing

A Trial of Regorafenib Plus Lorigerlimab as Neoadjuvant Therapy for Patients With pMMR/MSS, Resectable, Lung-limited Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)WithdrawnNCT07223567
What this trial is testing

A Trial of Regorafenib Plus Lorigerlimab in Patients With Locally Recurrent or Regrowing pMMR/MSS Localized Rectal Cancer

Who this might be right for
Rectal CancerRectal Cancer Recurrent
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07621562
What this trial is testing

Tafolecimab Combined With Sintilimab and SOX in the Treatment of pMMR/MSS Gastric Cancer

Who this might be right for
Gastric AdenocarcinomaEsophagogastric Juction CancerProficient Mismatch Repair
First Affiliated Hospital of Zhejiang University 30
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