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Results for “MSS Locally Advanced Rectal Adenocarcinoma”

14 trials

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Showing 14 of 14 results

Large-scale testing (Phase 3)Looking for participantsNCT05752136
What this trial is testing

Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma

Who this might be right for
Rectal Cancer
Sir Run Run Shaw Hospital 108
Testing effectiveness (Phase 2)Study completedNCT05216653
What this trial is testing

Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma (PRECAM)

Who this might be right for
MSS Locally Advanced Rectal Adenocarcinoma
Sir Run Run Shaw Hospital 32
Testing effectiveness (Phase 2)Looking for participantsNCT07458529
What this trial is testing

Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer, AdenocarcinomaNeoadjuvant TherapyImmunotherapy+3 more
Seventh Medical Center of PLA General Hospital 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06872606
What this trial is testing

Short-Course Radiotherapy Combined with Intracavitary Brachytherapy Followed by Pucotenlimab, Bevacizumab, Oxaliplatin, and Trifluridine/Tipiracil (TAS-102) for Total Neoadjuvant Therapy of Microsatellite Stable (MSS) Locally Advanced Low Rectal Cancer

Who this might be right for
Rectal Adenocarcinoma
Sir Run Run Shaw Hospital 33
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07779694
What this trial is testing

16-Hour Fasting Plus Serplulimab and CAPEOX as Neoadjuvant Therapy in pMMR/MSS Advanced Mid-to-Low Rectal Cancer

Who this might be right for
pMMR/MSSLocally Advanced Rectal CarcinomaFasting, Intermittent
Zhejiang University 51
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06919510
What this trial is testing

A Phase ll Study of Neoadjuvant Short-course Radiotherapy Followed by Ivonescimab and Chemotherapy in pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Rectal Adenocarcinoma
Sun Yat-sen University 90
Testing effectiveness (Phase 2)UnknownNCT05858567
What this trial is testing

Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal Adenocarcinoma

Who this might be right for
Rectal Cancer
Sir Run Run Shaw Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07765667
What this trial is testing

NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARC

Who this might be right for
Rectal AdenocarcinomaHigh-Risk CancerMSS
Sixth Affiliated Hospital, Sun Yat-sen University 100
Testing effectiveness (Phase 2)Looking for participantsNCT05919264
What this trial is testing

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Who this might be right for
CancerColorectal CancerSolid Tumor+12 more
Parabilis Medicines, Inc. 619
Testing effectiveness (Phase 2)Looking for participantsNCT07448142
What this trial is testing

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer (CRC)
Sun Yat-sen University 50
Large-scale testing (Phase 3)Looking for participantsNCT06791512
What this trial is testing

MFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC

Who this might be right for
Colorectal Cancer (CRC)pMMR/MSS Adenocarcinoma of the Colon or Rectum
Jun Huang 166
Testing effectiveness (Phase 2)Looking for participantsNCT05731726
What this trial is testing

Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer

Who this might be right for
pMMRMSSMSI-L+1 more
Zhejiang University 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06599827
What this trial is testing

Neoadjuvant Moderately Hypofractionated Radiotherapy Combined with Chemotherapy and Immunotherapy for High-risk LARC

Who this might be right for
Rectal Cancer
Shanghai Zhongshan Hospital 54
Testing effectiveness (Phase 2)Looking for participantsNCT07669220
What this trial is testing

A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial)

Who this might be right for
Rectal AdenocarcinomaHigh-risk Locally AdvancedShort-course Radiotherapy (SCRT)+2 more
Sixth Affiliated Hospital, Sun Yat-sen University 76