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Results for “MTAP Negative”

17 trials

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Showing 17 of 17 results

Testing effectiveness (Phase 2)Looking for participantsNCT06137144
What this trial is testing

AZD3470 as Monotherapy and in Combination With Anticancer Agents in Participants With Relapsed/Refractory Haematologic Malignancies.

Who this might be right for
LymphomaNon-HodgkinHodgkin Lymphoma
AstraZeneca 110
Testing effectiveness (Phase 2)Study completedNCT00062283
What this trial is testing

Alanosine in Treating Patients With Cancer

Who this might be right for
Lung CancerMalignant MesotheliomaPancreatic Cancer+1 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT00075894
What this trial is testing

Alanosine in Treating Patients With Progressive or Recurrent Malignant Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
National Cancer Institute (NCI) 18
Not applicableStudy completedNCT03361358
What this trial is testing

Pre-Screening Study to Identify MTAP Loss in Advanced Solid Tumors or Lymphoma

Who this might be right for
Advanced Solid TumorsLymphoma
Agios Pharmaceuticals, Inc. 44
Testing effectiveness (Phase 2)Looking for participantsNCT06922591
What this trial is testing

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Who this might be right for
PDACPDAC - Pancreatic Ductal AdenocarcinomaNSCLC+5 more
Tango Therapeutics, Inc. 183
Testing effectiveness (Phase 2)Looking for participantsNCT06971523
What this trial is testing

A Phase I/II Clinical Study of CTS3497 in Patients With MTAP Deficient Malignacies

Who this might be right for
Solid TumorLymphoma
CytosinLab Therapeutics Co., Ltd. 224
Very early researchLooking for participantsNCT06883747
What this trial is testing

Clinical Trial of BMS-986504 in Recurrent GBM Patients

Who this might be right for
Glioblastoma WHO Grade IV
Nader Sanai 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT05335941
What this trial is testing

Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma

Who this might be right for
Urothelial CarcinomaMetastatic Cancer
M.D. Anderson Cancer Center 10
Early research (Phase 1)Looking for participantsNCT07288957
What this trial is testing

A Early Study of ABSK131 in Patients With Advanced/Metastatic Solid Tumors

Who this might be right for
Solid Tumors (Phase 1)
Abbisko Therapeutics Co, Ltd 266
Testing effectiveness (Phase 2)Looking for participantsNCT06810544
What this trial is testing

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Who this might be right for
Non Small Cell Lung CancerGlioma Glioblastoma MultiformeGlioma, Malignant+4 more
Tango Therapeutics, Inc. 191
Early research (Phase 1)Looking for participantsNCT07382544
What this trial is testing

Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss

Who this might be right for
Advanced CancerSolid Tumor
M.D. Anderson Cancer Center 36
Early research (Phase 1)Looking for participantsNCT07277413
What this trial is testing

IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

Who this might be right for
NSCLC AdenocarcinomaGastroesophageal Cancer (GC)Gastric Adenocarcinoma+8 more
IDEAYA Biosciences 260
Early research (Phase 1)Looking for participantsNCT06589596
What this trial is testing

An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BeOne Medicines 244
Testing effectiveness (Phase 2)Looking for participantsNCT06130553
What this trial is testing

AZD3470, a PRMT5 Inhibitor, in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumors That Are MTAP Deficient
AstraZeneca 234
Early research (Phase 1)Ended earlyNCT03435250
What this trial is testing

Study of AG-270 in Participants With Advanced Solid Tumors or Lymphoma With MTAP Loss

Who this might be right for
Advanced Solid TumorsLymphoma
Institut de Recherches Internationales Servier 123
Testing effectiveness (Phase 2)Active Not RecruitingNCT03744793
What this trial is testing

Pemetrexed and Avelumab in Treating Patients With MTAP-Deficient Metastatic Urothelial Cancer

Who this might be right for
Infiltrating Bladder Urothelial Carcinoma Sarcomatoid VariantInfiltrating Bladder Urothelial Carcinoma With Glandular DifferentiationInfiltrating Bladder Urothelial Carcinoma With Squamous Differentiation+4 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Looking for participantsNCT06922357
What this trial is testing

A Phase I/II of HRS-6719 in Patients With Advanced/Metastatic Solid Tumors

Who this might be right for
Advanced/Metastatic Solid Tumors
Shandong Suncadia Medicine Co., Ltd. 120
18