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Results for “MTAP-deleted Pancreatic Cancer”

13 trials

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Showing 13 of 13 results

Testing effectiveness (Phase 2)Looking for participantsNCT06914128
What this trial is testing

PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

Who this might be right for
MTAP-deleted Solid Tumors
Bayer 450
Early research (Phase 1)Active Not RecruitingNCT06360354
What this trial is testing

A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion (MTAPESTRY 103)

Who this might be right for
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Amgen 120
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07492680
What this trial is testing

BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

Who this might be right for
Solid Tumors
Bristol-Myers Squibb 260
Testing effectiveness (Phase 2)Looking for participantsNCT06922591
What this trial is testing

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Who this might be right for
PDACPDAC - Pancreatic Ductal AdenocarcinomaNSCLC+5 more
Tango Therapeutics, Inc. 183
Testing effectiveness (Phase 2)Active Not RecruitingNCT06188702
What this trial is testing

S095035 as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of MTAP

Who this might be right for
MTAP-deleted Solid Tumors
Servier Bio-Innovation LLC 60
Testing effectiveness (Phase 2)Looking for participantsNCT07283705
What this trial is testing

A Phase II Study Evaluating BMS-986504 in MTAP-deleted Pancreatic Cancer

Who this might be right for
Phase 2 StudyBMS-986504MTAP-deleted Pancreatic Cancer
M.D. Anderson Cancer Center 60
Testing effectiveness (Phase 2)Ended earlyNCT05275478
What this trial is testing

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Tango Therapeutics, Inc. 110
Large-scale testing (Phase 3)Active Not RecruitingNCT07076121
What this trial is testing

A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

Who this might be right for
Pancreatic Ductal Adenocarcinoma
Bristol-Myers Squibb 470
Testing effectiveness (Phase 2)Looking for participantsNCT05732831
What this trial is testing

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Tango Therapeutics, Inc. 225
Early research (Phase 1)Not Yet RecruitingNCT07583771
What this trial is testing

A Phase Ⅰ Study of CS08399 in Participants With MTAP-deleted Solid Tumors and Lymphoma

Who this might be right for
Pancreatic AdenocarcinomaNon Small Cell Lung CancerAdvanced Solid Tumors+2 more
Chipscreen Biosciences, Ltd. 186
Early research (Phase 1)Looking for participantsNCT05245500
What this trial is testing

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Who this might be right for
MesotheliomaNon Small Cell Lung CancerMalignant Peripheral Nerve Sheath Tumors+3 more
Bristol-Myers Squibb 336
Early research (Phase 1)Looking for participantsNCT07277413
What this trial is testing

IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

Who this might be right for
NSCLC AdenocarcinomaGastroesophageal Cancer (GC)Gastric Adenocarcinoma+10 more
IDEAYA Biosciences 260
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07594626
What this trial is testing

BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion

Who this might be right for
Metastatic Biliary Tract CarcinomaMetastatic Colon CarcinomaMetastatic Esophageal Carcinoma+5 more
Northwestern University 72