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Results for “Macitentan”

Showing 20 of 0 results

Post-approval studies (Phase 4)Study completedNCT02382016
What this trial is testing

PORtopulmonary Hypertension Treatment wIth maCitentan - a randOmized Clinical Trial

Who this might be right for
Portopulmonary Hypertension
Actelion 85
Large-scale testing (Phase 3)Ended earlyNCT04271475
What this trial is testing

Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension

Who this might be right for
Chronic Thromboembolic Pulmonary Hypertension
Actelion 127
Early research (Phase 1)Study completedNCT05433675
What this trial is testing

Two Macitentan Formulations in Healthy Adult Participants

Who this might be right for
Healthy
Actelion 28
Large-scale testing (Phase 3)Active Not RecruitingNCT04273945
What this trial is testing

Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 935
Large-scale testing (Phase 3)Ended earlyNCT03775421
What this trial is testing

An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients.

Who this might be right for
Congenital Heart Disease With Fontan Circulation
Actelion 112
Testing effectiveness (Phase 2)WithdrawnNCT01346930
What this trial is testing

Safety and Tolerability Study of Macitentan in Patients With Idiopathic Pulmonary Fibrosis

Who this might be right for
Idiopathic Pulmonary Fibrosis
Actelion
Not applicableStudy completedNCT03197688
What this trial is testing

Retrospective Chart Review of First-time Opsumit® (Macitentan) Users in the United States

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 2,200
Early research (Phase 1)Study completedNCT05392530
What this trial is testing

Two Different Test Formulations Compared to the Reference Formulation of Macitentan in Healthy Adult Participants

Who this might be right for
Healthy
Actelion 23
Very early researchLooking for participantsNCT07392281
What this trial is testing

Efficacy and Mechanisms of Macitentan for Non-Coronary Obstructive Angina

Who this might be right for
Non-Coronary Obstructive Angina
China-Japan Friendship Hospital 40
Large-scale testing (Phase 3)Study completedNCT02112487
What this trial is testing

Extension of the Psychometric Validation Study ORCHESTRA in Patients With PAH

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 88
Early research (Phase 1)Study completedNCT05236231
What this trial is testing

Fixed Dose Combination of Macitentan/Tadalafil (10 mg/20 mg) Compared to the Reference Free Combination of Macitentan and Tadalafil in Healthy Adult Participants

Who this might be right for
Healthy
Actelion 40
Large-scale testing (Phase 3)Ended earlyNCT01474122
What this trial is testing

Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients

Who this might be right for
Digital Ulcers
Actelion 265
Early research (Phase 1)Study completedNCT03215966
What this trial is testing

Compare the Macitentan-tadalafil Fixed Dose Combination Tablet Relative to the Concomitant Administration of the Reference Tablets of Macitentan and Tadalafil in Healthy Subjects

Who this might be right for
Healthy Subjects
Actelion 38
Post-approval studies (Phase 4)Ended earlyNCT02885012
What this trial is testing

Crossover Study From Macitentan or Bosentan Over to Ambrisentan

Who this might be right for
Pulmonary Arterial Hypertension
Medical University of South Carolina 3
Not applicableStudy completedNCT01266265
What this trial is testing

Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies

Who this might be right for
Pulmonary Arterial Hypertension
United Therapeutics 1,333
Early research (Phase 1)Study completedNCT04540744
What this trial is testing

Macitentan/Tadalafil Combination Administered a Fixed-dose Combination Formulation Compared to the Reference Free Combination of Macitentan and Tadalafil

Who this might be right for
Healthy
Janssen Research & Development, LLC 18
Early research (Phase 1)Ended earlyNCT02254954
What this trial is testing

Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma
Actelion 30
Testing effectiveness (Phase 2)Study completedNCT02554903
What this trial is testing

Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation

Who this might be right for
Pulmonary Hypertension
Actelion 57
Large-scale testing (Phase 3)Study completedNCT00667823
What this trial is testing

Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 550
Large-scale testing (Phase 3)Study completedNCT00660179
What this trial is testing

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 742
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