Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Major Depressive Disorder and Irritability”

11 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 11 of 11 results

Early research (Phase 1)Active Not RecruitingNCT07452692
What this trial is testing

Assess the Skin Irritation and Sensitization of Selegiline TDS in Healthy Subjects

Who this might be right for
Major Depressive Disorder (MDD)
Corium Innovations, Inc. 232
Post-approval studies (Phase 4)Not Yet RecruitingNCT07544966
What this trial is testing

Teen Vulnerability to Irritability: Brain and Estrogen Changes

Who this might be right for
Depression - Major Depressive DisorderIrritability
University of North Carolina, Chapel Hill 50
Large-scale testing (Phase 3)Active Not RecruitingNCT05174273
What this trial is testing

Neurocognitive Effects of FMT in MDD Patients With and Without IBS

Who this might be right for
Major Depressive DisorderIrritable Bowel Syndrome
Valerie Taylor 133
Large-scale testing (Phase 3)WithdrawnNCT02212613
What this trial is testing

Brexpiprazole (OPC 34712) Trial in the Treatment of Adults With Major Depressive Disorder and Irritability

Who this might be right for
Major Depressive Disorder and Irritability
Otsuka Pharmaceutical Development & Commercialization, Inc.
Post-approval studies (Phase 4)WithdrawnNCT01916200
What this trial is testing

Efficacy and Safety of Paroxetine Controlled Release for Major Depressive Disorder in Irritable Bowel Syndrome Patients

Who this might be right for
Depressive Disorder
GlaxoSmithKline
Post-approval studies (Phase 4)Study completedNCT01754493
What this trial is testing

Open Trial of Duloxetine in Outpatients With Irritable Bowel Syndrome Symptoms and Co-Morbid Major Depression

Who this might be right for
Major DepressionIrritable Bowel Syndrome
New York State Psychiatric Institute 17
Post-approval studies (Phase 4)Ended earlyNCT01337609
What this trial is testing

Study of Probiotic GanedenBC30 for Irritable Bowel Syndrome and Major Depressive Disorder

Who this might be right for
Major Depressive DisorderIrritable Bowel Syndrome
Massachusetts General Hospital 5
Large-scale testing (Phase 3)Study completedNCT01942785
What this trial is testing

Study of Brexpiprazole as Adjunctive Treatment of Irritability in Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant Therapy

Who this might be right for
Major Depressive DisorderIrritability
H. Lundbeck A/S 55
Not applicableEnrolling By InvitationNCT07345377
What this trial is testing

Study on Treatment Mechanisms and Efficacy Prediction of Individualized Transcranial Magnetic Stimulation in Adults With Irritable Bowel Syndrome Using Multimodal MRI and High-Throughput Sequencing

Who this might be right for
Irritable Bowel Syndrome (IBS)PainDepressive Disorder, Major, Moderate
The Affiliated Hospital of Hangzhou Normal University 160
Not applicableTemporarily pausedNCT04031469
What this trial is testing

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

Who this might be right for
Gut MicrobiomeGastrointestinal MicrobiomeAutism+77 more
ProgenaBiome 1,000
Post-approval studies (Phase 4)Study completedNCT01464229
What this trial is testing

Iloperidone Augmentation of SSRIs for Patients With Major Depressive Disorder With Residual Anger and Irritability

Who this might be right for
Major Depressive Disorder
Maurizio Fava, MD 20