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Results for “Major High Risk Operations”

148 trials

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Showing 20 of 148 results

Testing effectiveness (Phase 2)Ended earlyNCT00880542
What this trial is testing

Sorafenib and Ifosfamide in Treating Patients With High-Grade Soft Tissue Sarcoma or Bone Sarcoma That Can Be Removed by Surgery

Who this might be right for
Sarcoma
Jonsson Comprehensive Cancer Center 7
Early research (Phase 1)Ended earlyNCT00683553
What this trial is testing

A Dose Escalation and Safety Study of I5NP to Prevent Acute Kidney Injury (AKI) in Patients at High Risk of AKI Undergoing Major Cardiovascular Surgery (QRK.004)

Who this might be right for
Acute Renal FailureAcute Kidney Injury
Quark Pharmaceuticals 3
Not applicableStudy completedNCT04345354
What this trial is testing

Observational Study of the Value of Using Obstructive Sleep Apnea-hypopnea Syndrome (CPAP) Ventilation on the Occurrence of Respiratory and Cardiovascular Complications in Patients at High Risk of Obstructive Apnea Syndrome During Postoperative Sleep Surgery of a Major Abdominal Surgery.

Who this might be right for
Major Abdominal Surgery
Poitiers University Hospital 48
Testing effectiveness (Phase 2)Ended earlyNCT04209790
What this trial is testing

Neoadjuvant Chemoradiation for Resectable Glioblastoma

Who this might be right for
GlioblastomaSurgeryHigh Grade Glioma
Geisinger Clinic 2
Testing effectiveness (Phase 2)Ended earlyNCT05316688
What this trial is testing

A Fluorescent Tumor Marking Agent, Tozuleristide, for Imaging Oral Cavity Squamous Cell Cancer and High-Grade Oral Cavity Dysplasia During Surgery

Who this might be right for
Oral Cavity Squamous Cell CarcinomaStage I Lip and Oral Cavity Cancer AJCC v8Stage II Lip and Oral Cavity Cancer AJCC v8+2 more
University of Washington 8
Not applicableStudy completedNCT05752474
What this trial is testing

Multi-Component Prehabilitation for Major Elective Surgery

Who this might be right for
FrailtyFunctional RecoveryPrehabilitation
Beth Israel Deaconess Medical Center 30
Not applicableActive Not RecruitingNCT05275218
What this trial is testing

Effect of an Intervention to Prevent Acute Kidney Injury Versus Standard Care in High-risk Patients After Major Surgery

Who this might be right for
Acute Kidney Injury (Nontraumatic)
University Hospital Muenster 480
Not applicableActive Not RecruitingNCT05934851
What this trial is testing

A Study Evaluating the Effect of Frozen-Section Directed Excision Surgery on Vulvar Dysplasia

Who this might be right for
Vulvar NeoplasmDysplasia Vulvar
Wake Forest University Health Sciences 112
Not applicableStudy completedNCT02276547
What this trial is testing

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System

Who this might be right for
Mitral Valve Regurgitation
Shockwave Medical, Inc. 27
Large-scale testing (Phase 3)UnknownNCT01039298
What this trial is testing

Efficacy of Optically-guided Surgery in the Management of Early-staged Oral Cancer - COOLS TRIAL

Who this might be right for
Oral CancerHigh-grade Precancer
University of British Columbia 200
Testing effectiveness (Phase 2)Looking for participantsNCT06504147
What this trial is testing

Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery

Who this might be right for
Peritoneal CarcinomatosisOvarian Cancer
Oncoinvent Solutions AS 114
Large-scale testing (Phase 3)Study completedNCT00002641
What this trial is testing

Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma

Who this might be right for
Endometrial CancerKidney CancerOvarian Cancer+2 more
European Organisation for Research and Treatment of Cancer - EORTC 350
Not applicableStudy completedNCT05129566
What this trial is testing

Evaluation of Axial Stability of Two Models of Intraocular Lenses in Patients With an Eye Length More Than 26 mm

Who this might be right for
Cataract SenileMyopia, High-GradeCorneal Astigmatism
The S.N. Fyodorov Eye Microsurgery State Institution 78
Large-scale testing (Phase 3)Study completedNCT00002459
What this trial is testing

Radiation Therapy or No Further Treatment Following Surgery in Treating Patients With Cancer of the Uterus

Who this might be right for
Endometrial CancerSarcoma
European Organisation for Research and Treatment of Cancer - EORTC 224
Very early researchNot Yet RecruitingNCT07778602
What this trial is testing

Safety and Feasibility of First-line Avutometinib and Defactinib in Patients With Newly Diagnosed High-grade Gliomas

Who this might be right for
MGMT-unmethylated Glioblastoma (GBM)IDH Wildtype Glioblastoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 22
Not applicableStudy completedNCT04737577
What this trial is testing

Glioma Supra Marginal Incision Trial

Who this might be right for
High Grade Glioma
Sunnybrook Health Sciences Centre 44
Not applicableStudy completedNCT05648279
What this trial is testing

Personalized Hemodynamic Management in High-risk Major Abdominal Surgery

Who this might be right for
Cardiac OutputSurgeryPostoperative Complications+1 more
Universitätsklinikum Hamburg-Eppendorf 1,128
Testing effectiveness (Phase 2)Looking for participantsNCT04644289
What this trial is testing

WoO: Window of Opportunity Trial of Olaparib and Durvalumab in Histologically Proven EOC

Who this might be right for
Epithelial Ovarian Cancer
AGO Research GmbH 60
Not applicableStudy completedNCT06372704
What this trial is testing

Is the HIFEM Procedure an Effective Treatment for Men With Post-prostatectomy Incontinence?

Who this might be right for
Prostate CancerIncontinencePelvic Floor Muscle Weakness
Kirsehir Ahi Evran Universitesi 27
Not applicableLooking for participantsNCT07519733
What this trial is testing

Preoperative Exercise Testing and Perioperative Outcomes

Who this might be right for
Postoperative Complications (Cardiopulmonary)
Yale University 992
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