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Results for “Malignant Glioma (WHO Grade III or IV)”

26 trials

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Showing 20 of 26 results

Early research (Phase 1)WithdrawnNCT00458744
What this trial is testing

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Children's Oncology Group
Early research (Phase 1)Looking for participantsNCT04573140
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

Who this might be right for
Adult GlioblastomaHigh Grade GliomaWHO Grade III or IV Malignant Glioma
University of Florida 28
Very early researchStudy completedNCT02278510
What this trial is testing

Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma

Who this might be right for
Malignant GliomaWHO Grade III or IV Recurrent Glioma
Michael Vogelbaum, MD, PhD 3
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07206849
What this trial is testing

Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)

Who this might be right for
High Grade Glioma (HGG) of the Brain With BRAF AberrationHigh Grade Glioma (III or IV)Diffuse Intrinsic Pontine Glioma+4 more
Nationwide Children's Hospital 79
Testing effectiveness (Phase 2)Study completedNCT00492089
What this trial is testing

Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic EpendymomaAdult Anaplastic Meningioma+84 more
National Cancer Institute (NCI) 11
Very early researchActive Not RecruitingNCT06333899
What this trial is testing

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 15
Not applicableNot Yet RecruitingNCT07366892
What this trial is testing

Leica Microsystems Sponsored PMCF Study to Collect and Confirm Clinical Data on the Performance of the GLOW400 Device When Used in Accordance With Its Intended Use

Who this might be right for
Suspected Grade III and IV Gliomas Requiring Surgical InterventionNeurosurgical ProcedureGlioma+1 more
Leica Microsystems (Schweiz) AG 37
Testing effectiveness (Phase 2)Study completedNCT00006102
What this trial is testing

Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma

Who this might be right for
Brain and Central Nervous System TumorsLymphomaNeuroblastoma+3 more
National Cancer Institute (NCI) 200
Testing effectiveness (Phase 2)Looking for participantsNCT06703255
What this trial is testing

HX301 in Patients with High-grade Giloma

Who this might be right for
Glioma
Hangzhou Hanx Biopharmaceuticals, Ltd. 72
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Very early researchEnded earlyNCT02500459
What this trial is testing

Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection

Who this might be right for
Brain TumorHigh Grade Glioma
Michael Vogelbaum, MD, PhD 9
Very early researchEnded earlyNCT03927274
What this trial is testing

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

Who this might be right for
Glioma of Brain
H. Lee Moffitt Cancer Center and Research Institute 3
Early research (Phase 1)Active Not RecruitingNCT03389230
What this trial is testing

Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma

Who this might be right for
GlioblastomaMalignant GliomaRecurrent Glioma+2 more
City of Hope Medical Center 29
Early research (Phase 1)Looking for participantsNCT06964737
What this trial is testing

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

Who this might be right for
Recurrent Malignant GliomaRecurrent WHO Grade 3 GliomaRecurrent WHO Grade 4 Glioma+3 more
Ohio State University Comprehensive Cancer Center 30
Testing effectiveness (Phase 2)Study completedNCT01204684
What this trial is testing

Dendritic Cell Vaccine for Patients With Brain Tumors

Who this might be right for
GliomaAnaplastic AstrocytomaAnaplastic Astro-oligodendroglioma+1 more
Jonsson Comprehensive Cancer Center 24
Early research (Phase 1)Ended earlyNCT01989052
What this trial is testing

Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma

Who this might be right for
Malignant Glioma (WHO Grade III or IV)
Annick Desjardins 9
Early research (Phase 1)Looking for participantsNCT06666712
What this trial is testing

Chronic CED of TPT for Recurrent Malignant Glioma

Who this might be right for
Brain Tumor, RecurrentMalignant Glioma (WHO Grade III or IV)IDH1/IDH2 Mutation
Jeffrey N. Bruce 6
Testing effectiveness (Phase 2)Ended earlyNCT00788125
What this trial is testing

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
City of Hope Medical Center 7
Not applicableStudy completedNCT00897611
What this trial is testing

Tumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma

Who this might be right for
High Grade Glioma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 42
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
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