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Results for “Malignant Neoplasms of Thyroid and Other Endocrine Glands”

32 trials

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Showing 20 of 32 results

Testing effectiveness (Phase 2)Study completedNCT02383927
What this trial is testing

Phase II Study of Tipifarnib in Squamous Head and Neck Cancer With HRAS Mutations

Who this might be right for
Thyroid CancerSquamous Cell Carcinoma Head and Neck Cancer (HNSCC)HRAS Mutant Tumor+1 more
Kura Oncology, Inc. 63
Testing effectiveness (Phase 2)Active Not RecruitingNCT02867592
What this trial is testing

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Who this might be right for
Adrenal Cortical CarcinomaAlveolar Soft Part SarcomaCentral Nervous System Neoplasm+41 more
National Cancer Institute (NCI) 109
Testing effectiveness (Phase 2)Active Not RecruitingNCT03157128
What this trial is testing

Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)

Who this might be right for
Non-Small Cell Lung CancerMedullary Thyroid CancerColon Cancer+1 more
Eli Lilly and Company 857
Not applicableStudy completedNCT00342407
What this trial is testing

The Incidence of Breast and Other Cancers Among Female Flight Attendants

Who this might be right for
Thyroid CancerBreast CancerNon-Melanoma Skin Cancer+1 more
National Cancer Institute (NCI) 6,093
Early research (Phase 1)Active Not RecruitingNCT05907304
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 86
Not applicableLooking for participantsNCT07072143
What this trial is testing

An International Study on Pediatric Patients With Rare Tumors.

Who this might be right for
Paraganglioma/ PhaeochromocytomaMelanoma and Other Malignant Neoplasms of SkinGastrointestinal Stromal Tumor (GIST)+11 more
Azienda Ospedaliera di Padova 6,250
Not applicableApproved For MarketingNCT03906331
What this trial is testing

Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) Activation

Who this might be right for
Non Small Cell Lung CancerMedullary Thyroid CancerColon Cancer+4 more
Eli Lilly and Company
Early research (Phase 1)Looking for participantsNCT03093909
What this trial is testing

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

Who this might be right for
Malignant Neoplasm of Bone and Articular CartilageMalignant Neoplasms of Female Genital OrgansMalignant Neoplasms of Independent (Primary) Multiple Sites+7 more
M.D. Anderson Cancer Center 44
Testing effectiveness (Phase 2)Ended earlyNCT04985604
What this trial is testing

Tovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid Tumors

Who this might be right for
MelanomaSolid TumorCRAF Gene Amplification+20 more
Day One Biopharmaceuticals, Inc. 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT04280081
What this trial is testing

Selpercatinib (LY3527723) in Participants With Advanced Solid Tumors Including RET Fusion-positive Solid Tumors, Medullary Thyroid Cancer and Other Tumors With RET Activation

Who this might be right for
Solid TumorMedullary Thyroid Cancer
Eli Lilly and Company 77
Not applicableUnknownNCT03896958
What this trial is testing

The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)

Who this might be right for
Cancer, All TypesCancer of LiverCancer of Stomach+42 more
SpeciCare 1,000
Testing effectiveness (Phase 2)Looking for participantsNCT05786924
What this trial is testing

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Who this might be right for
Non-small Cell Lung CancerHistiocytic NeoplasmHistiocytosis+29 more
Institut de Recherches Internationales Servier 554
Testing effectiveness (Phase 2)Active Not RecruitingNCT03449108
What this trial is testing

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

Who this might be right for
Bone SarcomaDedifferentiated ChondrosarcomaGiant Cell Tumor of Bone+13 more
M.D. Anderson Cancer Center 30
Not applicableStudy completedNCT00339716
What this trial is testing

Scientific Protocol for the Study of Thyroid Cancer and Other Thyroid Disease in Belarus Following the Chernobyl Accident

Who this might be right for
Thyroid CancerNon-Cancer Thyroid DiseaseNon Thyroid Cancer
National Cancer Institute (NCI) 19,456
Testing effectiveness (Phase 2)Study completedNCT03037385
What this trial is testing

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors

Who this might be right for
RET-altered Non Small Cell Lung CancerMedullary Thyroid CancerRET-altered Papillary Thyroid Cancer+37 more
Hoffmann-La Roche 590
Early research (Phase 1)Looking for participantsNCT04589624
What this trial is testing

An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy

Who this might be right for
Thyroid Gland Carcinoma
M.D. Anderson Cancer Center 42
Early research (Phase 1)Looking for participantsNCT04119024
What this trial is testing

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmMetastatic MelanomaPathologic Stage IIIC Cutaneous Melanoma AJCC v8+14 more
Anusha Kalbasi 18
Not applicableStudy completedNCT00341094
What this trial is testing

Scientific Protocol for the Study of Thyroid Cancer and Other Thyroid Disease in Ukraine Following the Chernobyl Accident

Who this might be right for
Thyroid CancerNon-Cancer Thyroid DiseaseNon Thyroid Cancer
National Cancer Institute (NCI) 23,143
Not applicableLooking for participantsNCT03160274
What this trial is testing

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

Who this might be right for
PheochromocytomaParagangliomaInherited Cancer Syndrome+5 more
The University of Texas Health Science Center at San Antonio 2,000
Early research (Phase 1)Active Not RecruitingNCT03162627
What this trial is testing

Selumetinib and Olaparib in Solid Tumors

Who this might be right for
Malignant Neoplasm of BreastMalignant Neoplasms of Digestive OrgansMalignant Neoplasms of Female Genital Organs+2 more
M.D. Anderson Cancer Center 90
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