Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Malignant Primary Brain Tumors”

126 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 126 results

Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Early research (Phase 1)Looking for participantsNCT03423628
What this trial is testing

Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Who this might be right for
Recurrent Glioblastoma MultiformePrimary Glioblastoma MultiformeBrain Neoplasms, Malignant+1 more
AstraZeneca 180
Not applicableEnded earlyNCT02967380
What this trial is testing

Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases

Who this might be right for
Adult Anaplastic (Malignant) MeningiomaAdult Anaplastic AstrocytomaAdult Anaplastic Ependymoma+22 more
University of Southern California 14
Testing effectiveness (Phase 2)Temporarily pausedNCT00003067
What this trial is testing

Biological Therapy in Treating Patients With Primary or Advanced Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Weill Medical College of Cornell University
Testing effectiveness (Phase 2)Ended earlyNCT00788125
What this trial is testing

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
City of Hope Medical Center 7
Early research (Phase 1)Study completedNCT01119599
What this trial is testing

RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

Who this might be right for
Acoustic SchwannomaAdult Anaplastic (Malignant) MeningiomaAdult Anaplastic Astrocytoma+26 more
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Study completedNCT00003464
What this trial is testing

Temozolomide in Treating Adults With Newly Diagnosed Primary Malignant Glioblastoma Multiforme

Who this might be right for
Brain and Central Nervous System Tumors
Duke University 50
Large-scale testing (Phase 3)Study completedNCT00005590
What this trial is testing

Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerExtragonadal Germ Cell Tumor+7 more
Cancer Research Campaign Clinical Trials Centre
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Testing effectiveness (Phase 2)Study completedNCT00463203
What this trial is testing

Bevacizumab and Irinotecan for Patients With Primary Brain Tumors and Progression After Standard Therapy

Who this might be right for
Brain NeoplasmsGlioma
Rigshospitalet, Denmark 54
Early research (Phase 1)Looking for participantsNCT07118176
What this trial is testing

Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers

Who this might be right for
Anal CarcinomaBladder CarcinomaBreast Carcinoma+31 more
Jonsson Comprehensive Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Not applicableStudy completedNCT02167204
What this trial is testing

18F-FLT PET/CT in Measuring Cell Proliferation in Patients With Brain Tumors

Who this might be right for
Metastatic Malignant Neoplasm in the BrainPrimary Brain NeoplasmRecurrent Brain Neoplasm
University of Washington 9
Not applicableStudy completedNCT00103038
What this trial is testing

Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases

Who this might be right for
Central Nervous System LymphomaMalignant GliomaMetastatic Malignant Neoplasm in the Brain
OHSU Knight Cancer Institute 155
Not applicableStudy completedNCT00477919
What this trial is testing

E-MOSAIC Electronic Tool to Monitor Symptoms

Who this might be right for
Cancer
Swiss Cancer Institute 264
Early research (Phase 1)Study completedNCT01158300
What this trial is testing

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 28
Testing effectiveness (Phase 2)Looking for participantsNCT07371663
What this trial is testing

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

Who this might be right for
Solid CancersNSCLC (Advanced Non-small Cell Lung Cancer)Gastric (Stomach) Cancer+2 more
Beijing Tide Pharmaceutical Co., Ltd 266
Testing effectiveness (Phase 2)Study completedNCT02095132
What this trial is testing

Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
Central Nervous System Embryonal Tumor With Rhabdoid FeaturesCentral Nervous System Embryonal Tumor, Not Otherwise SpecifiedCentral Nervous System Ganglioneuroblastoma+12 more
National Cancer Institute (NCI) 76
Early research (Phase 1)Study completedNCT01976910
What this trial is testing

Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer"

Who this might be right for
Advanced Cancer
DEKK-TEC, Inc. 23
Early research (Phase 1)Study completedNCT00005951
What this trial is testing

Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Duke University
Load More Results