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Results for “Maximum Tolerated Dose”

402 trials

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Showing 20 of 402 results

Early research (Phase 1)Ended earlyNCT03246854
What this trial is testing

DBPR112 in Patients With Head and Neck Cancer and EGFR Mutated Lung Cancer

Who this might be right for
Head and Neck CancerNSCLC
National Health Research Institutes, Taiwan 6
Testing effectiveness (Phase 2)UnknownNCT04247256
What this trial is testing

Trial of SCO-101 in Combination With FOLFIRI for Patients With Metastatic Colorectal Cancer (mCRC) With Acquired Resistance to FOLFIRI

Who this might be right for
Metastatic Colorectal Cancer
Scandion Oncology A/S 35
Early research (Phase 1)Study completedNCT00623870
What this trial is testing

RO5045337 [RG7112] in Patients With Hematologic Neoplasms.

Who this might be right for
Hematologic Neoplasms
Hoffmann-La Roche 116
Early research (Phase 1)Active Not RecruitingNCT03889795
What this trial is testing

Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors

Who this might be right for
Advanced Pancreatic CancerAdvanced Solid Tumor
Danae Hamouda, MD 15
Testing effectiveness (Phase 2)Study completedNCT00738829
What this trial is testing

Lenalidomide Dose Escalation Combined With Rituximab/Fludarabine in Untreated CLL

Who this might be right for
Leukemia, Lymphocytic, Chronic, B-Cell
Arbeitsgemeinschaft medikamentoese Tumortherapie 45
Early research (Phase 1)Study completedNCT00060645
What this trial is testing

Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

Who this might be right for
TumorsLymphomaMultiple Myeloma
Merck Sharp & Dohme LLC 33
Early research (Phase 1)Study completedNCT04811898
What this trial is testing

A Dose Escalation Study of LNA-i-Mir-221 for Cancer Treatment

Who this might be right for
Multiple Myeloma, RefractoryHepatocarcinomaAdvanced Solid Tumor
Azienda Ospedaliera Universitaria Mater Domini, Catanzaro 17
Testing effectiveness (Phase 2)Study completedNCT00708292
What this trial is testing

A Phase I-Ib/II Study to Determine the Maximum Tolerated Dose (MTD) of AUY922 Alone and in Combination With Bortezomib, With or Without Dexamethasone, in Patients With Relapsed or Refractory Multiple Myeloma.

Who this might be right for
Relapsed or Refractory Multiple Myeloma
Novartis Pharmaceuticals 29
Testing effectiveness (Phase 2)Not Yet RecruitingNCT04381130
What this trial is testing

A Phase I/IIa Study of EF-009 in Patients With Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Everfront Biotech Co., Ltd. 30
Testing effectiveness (Phase 2)Temporarily pausedNCT06628037
What this trial is testing

SN514-066b Enzyme in Deep Partial Thickness Burns

Who this might be right for
Burn Injury
SERDA bv 27
Early research (Phase 1)Ended earlyNCT02979392
What this trial is testing

Phase I Study of TENPA in Advanced Solid Cancer

Who this might be right for
Advanced Solid Tumor
Yung-Jue Bang 19
Testing effectiveness (Phase 2)Study completedNCT01283945
What this trial is testing

Study of Oral Lucitanib (E-3810), a Dual VEGFR-FGFR Tyrosine Kinase Inhibitor, in Patients With Solid Tumors

Who this might be right for
Solid Tumors
Institut de Recherches Internationales Servier 134
Early research (Phase 1)Study completedNCT01011972
What this trial is testing

Intravenous XMT-1107 in Patients With Advanced Solid Tumors

Who this might be right for
Neoplasm Metastasis
Mersana Therapeutics 52
Early research (Phase 1)Study completedNCT02081378
What this trial is testing

A Phase I Study of Oral Asciminib (ABL001) in Patients With CML or Ph+ ALL

Who this might be right for
Chronic Myelogenous LeukemiaPhiladelphia Chromosome-positive Acute Lymphoblastic Leukemia
Novartis Pharmaceuticals 326
Early research (Phase 1)Ended earlyNCT02250118
What this trial is testing

Intrapleural Bevacizumab After Pleural Drainage in the Context of Breast Cancer

Who this might be right for
Pleural Effusion, MalignantBreast Cancer
Institut Curie 1
Testing effectiveness (Phase 2)Ended earlyNCT01023880
What this trial is testing

Study to Determine the Maximum Tolerated Dose and Evaluate the Efficacy and Safety of CEP-18770 (Delanzomib) in Patients With Relapsed Multiple Myeloma Refractory to the Most Recent Therapy

Who this might be right for
Multiple Myeloma
Cephalon 62
Early research (Phase 1)Study completedNCT00594126
What this trial is testing

Safety and Dose Study of GRN163L Administered to Treat Patients With Refractory or Relapsed Multiple Myeloma

Who this might be right for
Multiple Myeloma
Geron Corporation 20
Early research (Phase 1)Study completedNCT00049023
What this trial is testing

Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsGastrointestinal Carcinoid TumorIslet Cell Tumor+4 more
O'Dorisio, M S 27
Early research (Phase 1)Study completedNCT00535522
What this trial is testing

A Safety and Pharmacokinetic Study of TAK-285 in Patients With Advanced Cancer

Who this might be right for
Cancer
Millennium Pharmaceuticals, Inc. 56
Early research (Phase 1)Temporarily pausedNCT00827203
What this trial is testing

A Safety Study to Determine the Maximum Tolerated Dose of Elesclomol Sodium in Patients With Solid Tumors

Who this might be right for
Metastatic Solid Tumors
Synta Pharmaceuticals Corp. 30
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