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Results for “Maximum Tolerated Dose”

402 trials

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Showing 20 of 402 results

Early research (Phase 1)Study completedNCT01011972
What this trial is testing

Intravenous XMT-1107 in Patients With Advanced Solid Tumors

Who this might be right for
Neoplasm Metastasis
Mersana Therapeutics 52
Early research (Phase 1)Active Not RecruitingNCT03889795
What this trial is testing

Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors

Who this might be right for
Advanced Pancreatic CancerAdvanced Solid Tumor
Danae Hamouda, MD 15
Testing effectiveness (Phase 2)Looking for participantsNCT05093907
What this trial is testing

Evaluate Safety and Efficacy of BEY1107 in Combination with Capecitabine in Patients with Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
BeyondBio Inc. 27
Testing effectiveness (Phase 2)Ended earlyNCT01997840
What this trial is testing

ACY-1215 (Ricolinostat) in Combination With Pomalidomide and Low-dose Dex in Relapsed-and-Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Celgene 103
Early research (Phase 1)UnknownNCT01818323
What this trial is testing

Phase I Trial: T4 Immunotherapy of Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
King's College London 30
Early research (Phase 1)Ended earlyNCT03332355
What this trial is testing

Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 2

Who this might be right for
Glioblastoma MultiformeAnaplastic Astrocytoma
Vanquish Oncology, Inc. 18
Early research (Phase 1)Study completedNCT03127735
What this trial is testing

BAY1436032 in Patients With Mutant IDH1(mIDH1) Advanced Acute Myeloid Leukemia (AML)

Who this might be right for
Leukemia, Myeloid, Acute
Bayer 27
Early research (Phase 1)Active Not RecruitingNCT07762001
What this trial is testing

Study to Evaluate the Safety and Tolerability of AD-NP1 in Healthy Human Adult Volunteers

Who this might be right for
Maximum Tolerated DoseDose Escalation
Arjun Deb, MD 36
Early research (Phase 1)Ended earlyNCT01668550
What this trial is testing

A Phase I Study of AZD0424 Alone and in Combination in Advanced Solid Tumours

Who this might be right for
Advanced Solid Tumours
Cancer Research UK 43
Large-scale testing (Phase 3)Study completedNCT03128515
What this trial is testing

Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas

Who this might be right for
Sickle Cell AnemiaSickle Cell DiseaseMalaria
Indiana University 187
Early research (Phase 1)Study completedNCT04257110
What this trial is testing

A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors

Who this might be right for
Locally Advanced/Metastatic HER2 Positive Solid Tumors
Bliss Biopharmaceutical (Hangzhou) Co., Ltd 117
Early research (Phase 1)Ended earlyNCT02687191
What this trial is testing

Safety and Tolerability of PF-05230907 in Intracerebral Hemorrhage

Who this might be right for
Intracerebral Hemorrhage
Pfizer 21
Early research (Phase 1)WithdrawnNCT04797468
What this trial is testing

The CD73 Inhibitor(HLX23) Alone in Participants With Solid Tumor

Who this might be right for
Advanced Solid Tumor
Shanghai Henlius Biotech
Early research (Phase 1)Study completedNCT01955564
What this trial is testing

A Phase I- Sequential Cohort Dosing to Determine Maximum Tolerated Dose in Healthy Male Volunteers.

Who this might be right for
Schizophrenia
Newron Pharmaceuticals SPA 54
Testing effectiveness (Phase 2)Study completedNCT00610649
What this trial is testing

Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder (174001/P05704/MK-8777-001)

Who this might be right for
Depression
Merck Sharp & Dohme LLC 54
Early research (Phase 1)Looking for participantsNCT04234048
What this trial is testing

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

Who this might be right for
T-cell LymphomaCutaneous/Peripheral T-Cell LymphomaPeripheral T-cell Lymphoma+8 more
SciTech Development, Inc. 46
Early research (Phase 1)Study completedNCT01728311
What this trial is testing

Open Label Study of BAY1082439 in Patients With Advanced Cancer

Who this might be right for
Neoplasms
Bayer 60
Testing effectiveness (Phase 2)Study completedNCT00708292
What this trial is testing

A Phase I-Ib/II Study to Determine the Maximum Tolerated Dose (MTD) of AUY922 Alone and in Combination With Bortezomib, With or Without Dexamethasone, in Patients With Relapsed or Refractory Multiple Myeloma.

Who this might be right for
Relapsed or Refractory Multiple Myeloma
Novartis Pharmaceuticals 29
Early research (Phase 1)Study completedNCT01132911
What this trial is testing

A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas

Who this might be right for
LymphomaSarcomaWilmsTumor+1 more
National Cancer Institute (NCI) 5
Early research (Phase 1)Study completedNCT01519817
What this trial is testing

Cancer Vaccine Targeting Brachyury Protein in Tumors

Who this might be right for
NeoplasmsMalignant Solid TumorsColon Neoplasms+1 more
National Cancer Institute (NCI) 34
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