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Results for “Maximum Tolerated Dose”

399 trials

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Showing 20 of 399 results

Early research (Phase 1)UnknownNCT01226407
What this trial is testing

Examine Maximum Tolerated Dose and Pharmacokinetic and Pharmacodynamic Profile

Who this might be right for
Solid Tumour
CrystalGenomics, Inc. 36
Early research (Phase 1)Looking for participantsNCT06922539
What this trial is testing

ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer

Who this might be right for
Small Cell Lung Cancer
SciTech Development, Inc. 44
Early research (Phase 1)Study completedNCT00551850
What this trial is testing

A Safety Study of an Oral EGFR Inhibitor, AV-412, Administered Three Times Weekly in Advanced Solid Tumor Patients

Who this might be right for
Advanced CancerRefractory Cancer
AVEO Pharmaceuticals, Inc. 37
Early research (Phase 1)Study completedNCT00155558
What this trial is testing

A Phase I Trial of HDFL48 in Recurrent or Metastatic Colorectal Cancers

Who this might be right for
Recurrent or Metastatic Colorectal Cancer
National Taiwan University Hospital 16
Early research (Phase 1)Active Not RecruitingNCT03889795
What this trial is testing

Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors

Who this might be right for
Advanced Pancreatic CancerAdvanced Solid Tumor
Danae Hamouda, MD 15
Early research (Phase 1)UnknownNCT03468751
What this trial is testing

Phase 1 Study of HLX10, a Monoclonal Antibody Targeting Programmed Death-1 (PD-1) in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Henlix, Inc 30
Early research (Phase 1)Looking for participantsNCT07104799
What this trial is testing

Momelotinib During and After HCT in Myelofibrosis

Who this might be right for
MyelofibrosisHematopoietic Cell Transplantation (HCT)
Massachusetts General Hospital 28
Early research (Phase 1)Study completedNCT01222780
What this trial is testing

To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer

Who this might be right for
SarcomaNeuroblastomaWilms Tumor+3 more
Acrotech Biopharma Inc. 22
Early research (Phase 1)Active Not RecruitingNCT05034497
What this trial is testing

Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastasis
Plus Therapeutics 18
Early research (Phase 1)Study completedNCT00716417
What this trial is testing

Study to Determine the Maximum Tolerated Dose of BIBW 2992 (Afatinib) When Combined With Cisplatin/Paclitaxel or Cisplatin/5-FU in Patients With Advanced Solid Tumours

Who this might be right for
Neoplasms
Boehringer Ingelheim 47
Testing effectiveness (Phase 2)UnknownNCT02630368
What this trial is testing

Metronomic CP and JX-594 in Patients With Advanced Breast Cancer and Advanced Soft-tissue Sarcoma (METROmaJX)

Who this might be right for
Solid TumorsSoft-tissue SarcomaBreast Cancer
Institut Bergonié 197
Early research (Phase 1)Ended earlyNCT04267939
What this trial is testing

ATR Inhibitor Elimusertib (BAY1895344) Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

Who this might be right for
Advanced Solid Tumors (Excluding Prostate Cancer)Ovarian Cancer
Bayer 14
Early research (Phase 1)WithdrawnNCT03496519
What this trial is testing

Assessing the Combination of Durvalumab (MEDI4736) and Trabectedin in Solid Tumors

Who this might be right for
Solid Tumor, Adult
University of Colorado, Denver
Early research (Phase 1)Study completedNCT00894894
What this trial is testing

Safety Study to Determine the Maximum Tolerated Dose, Pharmacokinetics and Pharmacodynamics of Oral MP470, a Multitargeted Tyrosine Kinase Inhibitor, in Patients With Solid Malignancies

Who this might be right for
Solid Tumors
Astex Pharmaceuticals, Inc. 22
Early research (Phase 1)Study completedNCT01815684
What this trial is testing

Assess the Safety, Tolerability and Effects of Single Ascending Doses of ASP3652 in Healthy Subjects

Who this might be right for
PharmacokineticsPharmacodynamicsHealthy Subjects+1 more
Astellas Pharma Europe B.V. 26
Early research (Phase 1)WithdrawnNCT01568632
What this trial is testing

Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma

Who this might be right for
Solid TumorsLymphoma
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT01335256
What this trial is testing

Clinical Study to Evaluate Safety and Maximum Tolerated Dose of BAY1000394 Given in a 4 Week on / 2 Week Off Schedule in Subjects With Advanced Malignancies

Who this might be right for
Neoplasms
Bayer 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT03564873
What this trial is testing

Omacetaxine + Azacitidine in Untreated Patients With High Grade MDS

Who this might be right for
High Grade Myelodysplastic Syndromes
University of Colorado, Denver 28
Testing effectiveness (Phase 2)Study completedNCT02511886
What this trial is testing

A Dose-Escalation Study to Determine the Maximum Tolerated Dose of Arbaclofen Placarbil in Subjects With Alcohol Use Disorder

Who this might be right for
Alcohol Use Disorder
Indivior Inc. 18
Testing effectiveness (Phase 2)Ended earlyNCT01023880
What this trial is testing

Study to Determine the Maximum Tolerated Dose and Evaluate the Efficacy and Safety of CEP-18770 (Delanzomib) in Patients With Relapsed Multiple Myeloma Refractory to the Most Recent Therapy

Who this might be right for
Multiple Myeloma
Cephalon 62
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