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Results for “Maximum Tolerated Dose”

399 trials

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Showing 20 of 399 results

Early research (Phase 1)Study completedNCT00001565
What this trial is testing

Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancy

Who this might be right for
Brain NeoplasmsNeuroblastoma
National Cancer Institute (NCI) 35
Early research (Phase 1)Study completedNCT00555100
What this trial is testing

Safety Study of Lenalidomide With and Without Dexamethasone in Japanese Subjects With Previously Treated Multiple Myeloma

Who this might be right for
Multiple Myeloma
Celgene 15
Early research (Phase 1)Study completedNCT00003430
What this trial is testing

L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Head and Neck CancerUnspecified Adult Solid Tumor, Protocol Specific
Memorial Sloan Kettering Cancer Center 40
Early research (Phase 1)Study completedNCT01737008
What this trial is testing

Dacomitinib Plus Radiotherapy, With and Without Cisplatin in Patients With Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
University Health Network, Toronto 12
Early research (Phase 1)Study completedNCT00875264
What this trial is testing

Open-Label Study to Determine the Maximum Tolerated Oral Dose of the Kinase Inhibitor CEP-11981 in Patients With Advanced Cancer

Who this might be right for
Cancer
Cephalon 43
Early research (Phase 1)UnknownNCT02352571
What this trial is testing

Safety Study of GC1118 (Recombinant Human Anti-EGFR Antibody) in Patients With Advanced Solid Cancer

Who this might be right for
Neoplasm MetastasisGastric CancerColorectal Cancer
Green Cross Corporation 72
Testing effectiveness (Phase 2)UnknownNCT04138381
What this trial is testing

Selinexor as Single Agent and With Imatinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (SeliGIST)

Who this might be right for
Maximum Tolerated DoseGISTMetastatic Adult Soft Tissue Sarcoma+2 more
Grupo Espanol de Investigacion en Sarcomas 30
Early research (Phase 1)Ended earlyNCT04267939
What this trial is testing

ATR Inhibitor Elimusertib (BAY1895344) Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

Who this might be right for
Advanced Solid Tumors (Excluding Prostate Cancer)Ovarian Cancer
Bayer 14
Early research (Phase 1)Study completedNCT06048367
What this trial is testing

Carbon Nanoparticle-Loaded Iron [CNSI-Fe(II)] in the Treatment of Advanced Solid Tumor

Who this might be right for
Advanced Solid TumorLung CancerPancreas Cancer+6 more
Sichuan Enray Pharmaceutical Sciences Company 19
Early research (Phase 1)Looking for participantsNCT06487481
What this trial is testing

Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma

Who this might be right for
Adrenocortical Carcinoma (ACC)Recurrent Adrenocortical Carcinoma (ACC)Recurrent Abdominal Adrenocortical Carcinoma (ACC)+2 more
National Cancer Institute (NCI) 32
Early research (Phase 1)Study completedNCT00594126
What this trial is testing

Safety and Dose Study of GRN163L Administered to Treat Patients With Refractory or Relapsed Multiple Myeloma

Who this might be right for
Multiple Myeloma
Geron Corporation 20
Testing effectiveness (Phase 2)Study completedNCT00632749
What this trial is testing

BI 811283 in Combination With Cytarabine in Previously Untreated AML Ineligible for Intensive Treatment

Who this might be right for
Leukemia, Myeloid, Acute
Boehringer Ingelheim 68
Early research (Phase 1)Study completedNCT02725957
What this trial is testing

Establish Safety and Maximum Tolerated Dose of IV Trehalose in Healthy Subjects

Who this might be right for
Healthy Volunteer Subjects
Bioblast Pharma Ltd. 24
Early research (Phase 1)Study completedNCT00060645
What this trial is testing

Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

Who this might be right for
TumorsLymphomaMultiple Myeloma
Merck Sharp & Dohme LLC 33
Testing effectiveness (Phase 2)Looking for participantsNCT05093907
What this trial is testing

Evaluate Safety and Efficacy of BEY1107 in Combination with Capecitabine in Patients with Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
BeyondBio Inc. 27
Early research (Phase 1)Study completedNCT01034475
What this trial is testing

Study to Evaluate Safety, Tolerability, Maximum Tolerated Dose (MTD), Efficacy, and Pharmacokinetics (PKs) of CPI-613 Given Twice Weekly for Three Consecutive Weeks in Patients With Advanced Hematologic Malignancies

Who this might be right for
Advanced Hematologic Malignancies
Wake Forest University Health Sciences 26
Early research (Phase 1)Study completedNCT01971515
What this trial is testing

First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumor
EMD Serono 101
Large-scale testing (Phase 3)Study completedNCT06005597
What this trial is testing

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHypercholesterolemiaFamilial Hypercholesterolemia+2 more
NewAmsterdam Pharma 407
Early research (Phase 1)Looking for participantsNCT07104799
What this trial is testing

Momelotinib During and After HCT in Myelofibrosis

Who this might be right for
MyelofibrosisHematopoietic Cell Transplantation (HCT)
Massachusetts General Hospital 28
Early research (Phase 1)Ended earlyNCT03035279
What this trial is testing

SC-006 and in Combination With ABBV-181 in Subjects With Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
AbbVie 29
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