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Results for “Maximum Tolerated Dose”

400 trials

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Showing 20 of 400 results

Testing effectiveness (Phase 2)Ended earlyNCT01023880
What this trial is testing

Study to Determine the Maximum Tolerated Dose and Evaluate the Efficacy and Safety of CEP-18770 (Delanzomib) in Patients With Relapsed Multiple Myeloma Refractory to the Most Recent Therapy

Who this might be right for
Multiple Myeloma
Cephalon 62
Early research (Phase 1)Study completedNCT02639091
What this trial is testing

Phase Ib Study of Anetumab Ravtansine in Combination With Pemetrexed and Cisplatin in Mesothelin-expressing Solid Tumors

Who this might be right for
Medical Oncology
Bayer 36
Early research (Phase 1)WithdrawnNCT01130623
What this trial is testing

A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors

Who this might be right for
SarcomaNeuroblastomaWilms Tumor+2 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT01518556
What this trial is testing

Safety and Efficacy Study of Idarubicin Dose Intensification to Treat Acute Myeloid Leukemia

Who this might be right for
Leukemia, Myeloid, Acute
Konkuk University Medical Center 49
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07247201
What this trial is testing

Integrating Allogeneic NK Cells in High-risk Advanced Stage III-IV Nasopharyngeal Cancer Patients

Who this might be right for
Nasopharyngeal Carcinoma (NPC)Minimal Residual DiseaseRecurrent Nasopharyngeal Carcinoma+1 more
Singapore General Hospital 31
Early research (Phase 1)Study completedNCT03311477
What this trial is testing

Evaluate the Safety and Pharmacokinetics ABBV-399 in Japanese Participants With Solid Tumors

Who this might be right for
Advanced Solid Tumors Cancer
AbbVie 9
Early research (Phase 1)Study completedNCT01976741
What this trial is testing

Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)

Who this might be right for
Neoplasms
Bayer 168
Early research (Phase 1)Study completedNCT00288431
What this trial is testing

Safety, Tolerability and Maximum Tolerated Dose of Oral AP23573 in Combination With Doxorubicin (8669-015)

Who this might be right for
CancerSarcoma
Merck Sharp & Dohme LLC 37
Testing effectiveness (Phase 2)Not Yet RecruitingNCT04381130
What this trial is testing

A Phase I/IIa Study of EF-009 in Patients with Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Everfront Biotech Co., Ltd. 30
Testing effectiveness (Phase 2)Ended earlyNCT03190967
What this trial is testing

T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery

Who this might be right for
Breast CancerBrain MetastasisBrain Cancer
National Cancer Institute (NCI) 12
Early research (Phase 1)UnknownNCT04262739
What this trial is testing

MTD, Safety and Efficacy of NYH817G and NYH100P in Monotherapy and Combination in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Haim Bio Co., Ltd. 42
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06628037
What this trial is testing

SN514-066b Enzyme in Deep Partial Thickness Burns

Who this might be right for
Burn Injury
SERDA bv 27
Early research (Phase 1)Study completedNCT00955812
What this trial is testing

STAT3 Inhibitor for Solid Tumors

Who this might be right for
Advanced CancerSolid Tumor
M.D. Anderson Cancer Center 24
Testing effectiveness (Phase 2)Study completedNCT00842335
What this trial is testing

A Phase 1/2, Open-Label, Dose-Escalation Study of JI-101, in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Jubilant Innovation Ltd. 18
Early research (Phase 1)Study completedNCT01259479
What this trial is testing

Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors

Who this might be right for
Solid TumorsBrain TumorsBrain Metastases
National Cancer Institute (NCI) 9
Early research (Phase 1)Study completedNCT00407498
What this trial is testing

Open Label Phase I Study of P276-00 in Patients With Advanced Refractory Neoplasms

Who this might be right for
Neoplasm
Piramal Enterprises Limited 50
Early research (Phase 1)Study completedNCT01576666
What this trial is testing

Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors

Who this might be right for
Dose EscalationSafetyPreliminary Efficacy+9 more
Novartis Pharmaceuticals 120
Early research (Phase 1)Study completedNCT01314105
What this trial is testing

BIBF 1120 + Carboplatin/Pegylated Liposomal Doxorubicin (PLD) in Patients With Advanced Ovarian Cancer, Fallopian Tube Carcinoma or Primary Peritoneal Cancer

Who this might be right for
Ovarian NeoplasmsPeritoneal Neoplasms
Boehringer Ingelheim 19
Early research (Phase 1)Study completedNCT00003430
What this trial is testing

L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Head and Neck CancerUnspecified Adult Solid Tumor, Protocol Specific
Memorial Sloan Kettering Cancer Center 40
Early research (Phase 1)Active Not RecruitingNCT02498912
What this trial is testing

Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors

Who this might be right for
Solid Tumors
Memorial Sloan Kettering Cancer Center 18
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