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Results for “Megalocephaly”

12 trials

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Showing 12 of 12 results

Not applicableNot Yet RecruitingNCT07142772
What this trial is testing

Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk

Who this might be right for
Megalocephaly
Assistance Publique - Hôpitaux de Paris 200
Not applicableLooking for participantsNCT02461446
What this trial is testing

Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

Who this might be right for
PTENASDAutism+2 more
Boston Children's Hospital 170
Testing effectiveness (Phase 2)Looking for participantsNCT05577754
What this trial is testing

Assessment of the Efficacy and Safety of Alpelisib (BYL719) in Pediatric and Adult Patients With Megalencephaly-CApillary Malformation Polymicrogyria Syndrome (MCAP)

Who this might be right for
Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)
Centre Hospitalier Universitaire Dijon 20
Not applicableStudy completedNCT04343560
What this trial is testing

MACS and Healthy Volunteers Bone Study

Who this might be right for
MACS Syndrome
Mayo Clinic 380
Not applicableStudy completedNCT01451983
What this trial is testing

Genetics, Brain Structure and Thinking Skills in Autism

Who this might be right for
Autism Spectrum Disorders
The Cleveland Clinic 138
Not applicableWithdrawnNCT04344626
What this trial is testing

Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery

Who this might be right for
EpilepsyFocal Cortical DysplasiaTuberous Sclerosis+7 more
University of California, Los Angeles
Not applicableStudy completedNCT05563831
What this trial is testing

National Evaluation of Patients With PIK3CA-Related Overgrowth Spectrum (PROS)

Who this might be right for
PIK3CA-related Overgrowth SpectrumCLOVES SyndromeKlippel Trenaunay Syndrome+6 more
Institut National de la Santé Et de la Recherche Médicale, France 28
Testing effectiveness (Phase 2)Looking for participantsNCT06789913
What this trial is testing

Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation

Who this might be right for
PIK3CA-Related Overgrowth Spectrum (PROS)Lymphatic MalformationsVascular Malformations+4 more
Relay Therapeutics, Inc. 277
Not applicableStudy completedNCT03548779
What this trial is testing

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2

Who this might be right for
Epilepsy; SeizureNeuromuscular DiseasesBrain Malformation+14 more
University of North Carolina, Chapel Hill 548
Not applicableLooking for participantsNCT02890641
What this trial is testing

Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies

Who this might be right for
Drug-resistant Focal Epilepsies in Pediatric Population
Fondation Ophtalmologique Adolphe de Rothschild 450
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07287202
What this trial is testing

Safety, Tolerability, and Pharmacokinetics of SVG103 (Paxalisib) in Focal Cortical Dysplasia Type II (FCD-II), Tuberous Sclerosis Complex (TSC) or Hemimegalencephaly (HME)

Who this might be right for
Focal Cortical DysplasiaTuberous Sclerosis Complex (TSC)Hemimegalencephaly
Sovargen 15
Not applicableLooking for participantsNCT06462430
What this trial is testing

PTEN Hamartoma Tumor Syndrome Pediatric Patient Registry

Who this might be right for
PTEN Hamartoma Tumor SyndromeMacrocephaly Autism Syndrome
Yale University 100