Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Melanoma Brain Metastasis”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT00039572
What this trial is testing

Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain

Who this might be right for
Brain and Central Nervous System TumorsMelanoma (Skin)Metastatic Cancer
Beth Israel Deaconess Medical Center
Testing effectiveness (Phase 2)Study completedNCT04700072
What this trial is testing

Substudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 56
Testing effectiveness (Phase 2)Looking for participantsNCT06194929
What this trial is testing

Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma

Who this might be right for
Cutaneous MelanomaBrain Metastases
University of Utah 33
Testing effectiveness (Phase 2)Study completedNCT00462982
What this trial is testing

Sunitinib in Treating Patients With Brain Metastases Caused by Kidney Cancer or Melanoma

Who this might be right for
Kidney CancerMelanoma (Skin)Metastatic Cancer
Memorial Sloan Kettering Cancer Center 8
Early research (Phase 1)Study completedNCT01703507
What this trial is testing

Phase I Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma

Who this might be right for
Recurrent MelanomaStage IV MelanomaTumors Metastatic to Brain
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 17
Testing effectiveness (Phase 2)Ended earlyNCT02974803
What this trial is testing

Concurrent Dabrafenib + Trametinib With Sterotactic Radiation in BRAF Mutation-Positive Malignant Melanoma and Brain Metastases

Who this might be right for
MelanomaBrain Metastases
Canadian Cancer Trials Group 6
Testing effectiveness (Phase 2)Ended earlyNCT01721603
What this trial is testing

Dabrafenib and Trametinib With Radiosurgery in Melanoma Brain Mets

Who this might be right for
BRAFV600E Melanoma Patients
University of California, San Francisco 2
Testing effectiveness (Phase 2)Ended earlyNCT02230306
What this trial is testing

Phase II Study of Cobimetinib in Combination With Vemurafenib in Active Melanoma Brain Metastases

Who this might be right for
Active Melanoma Brain Metastases
Melissa Burgess, MD 5
Testing effectiveness (Phase 2)Looking for participantsNCT04899908
What this trial is testing

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Who this might be right for
Brain CancerBrain MetastasesMelanoma+13 more
Brigham and Women's Hospital 134
Testing effectiveness (Phase 2)Study completedNCT02662725
What this trial is testing

Ipilimumab Combined With a Stereotactic Radiosurgery in Melanoma Patients With Brain Metastases

Who this might be right for
MelanomaBrain Metastasis
University Hospital, Lille 73
Testing effectiveness (Phase 2)Study completedNCT01497808
What this trial is testing

RADVAX™: A STRATIFIED PHASE I/II DOSE ESCALATION TRIAL OF HYPOFRACTIONATED RADIOTHERAPY FOLLOWED BY IPILIMUMAB IN METASTATIC MELANOMA

Who this might be right for
Metastatic Melanoma
Abramson Cancer Center at Penn Medicine 22
Testing effectiveness (Phase 2)Study completedNCT02038218
What this trial is testing

Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors

Who this might be right for
Primary Brain TumorsMetastatic Malignant Neoplasm to Brain
DEKK-TEC, Inc. 29
Testing effectiveness (Phase 2)Study completedNCT00072163
What this trial is testing

Temozolomide and Thalidomide in Treating Patients With Brain Metastases Secondary to Melanoma

Who this might be right for
Recurrent MelanomaStage IV MelanomaTumors Metastatic to Brain
National Cancer Institute (NCI) 50
Testing effectiveness (Phase 2)Ended earlyNCT01217411
What this trial is testing

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Who this might be right for
Adult Solid NeoplasmExtensive Stage Lung Small Cell CarcinomaHER2/Neu Negative+10 more
National Cancer Institute (NCI) 5
Testing effectiveness (Phase 2)Study completedNCT02681549
What this trial is testing

Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer (NSCLC)

Who this might be right for
MelanomaNon-small Cell Lung CancerBrain Metastasis
Yale University 41
Early research (Phase 1)WithdrawnNCT02145910
What this trial is testing

Vemurafenib Combined With Whole Brain Radiation Therapy or Radiosurgery in Patients With BRAF Mutation-Positive Melanoma and Brain Metastases

Who this might be right for
Recurrent MelanomaStage IV MelanomaTumors Metastatic to Brain
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Testing effectiveness (Phase 2)Ended earlyNCT04899921
What this trial is testing

Troriluzole or Placebo Plus Ipi Plus Nivo in Mel Brain Mets

Who this might be right for
MelanomaMetastatic Melanoma
Dana-Farber Cancer Institute 1
Testing effectiveness (Phase 2)Ended earlyNCT03911869
What this trial is testing

An Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis

Who this might be right for
Brain Metastases
Pfizer 13
Early research (Phase 1)Ended earlyNCT01950195
What this trial is testing

SRS (Stereotactic Radiosurgery) Plus Ipilimumab

Who this might be right for
Newly Diagnosed Melanoma Metastases in the Brain and Spine
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 4
Early research (Phase 1)Ended earlyNCT00937482
What this trial is testing

Cediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer

Who this might be right for
Male Breast CancerStage IV Breast CancerStage IV Melanoma+7 more
National Cancer Institute (NCI) 18
Next Page