Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Melanoma and Brain Metastases”

120 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 120 results

Testing effectiveness (Phase 2)UnknownNCT02452294
What this trial is testing

Buparlisib in Melanoma Patients Suffering From Brain Metastases (BUMPER)

Who this might be right for
Malignant MelanomaMetastases
University Hospital Tuebingen 22
Not applicableActive Not RecruitingNCT04785521
What this trial is testing

Glutamate Excitotoxicity in Brain Metastases From Lung, Breast and Melanoma Treated With Stereotactic Radiosurgery

Who this might be right for
Brain Metastases, Adult
IRCCS San Raffaele 100
Not applicableStudy completedNCT00477919
What this trial is testing

E-MOSAIC Electronic Tool to Monitor Symptoms

Who this might be right for
Cancer
Swiss Cancer Institute 264
Testing effectiveness (Phase 2)Ended earlyNCT04789668
What this trial is testing

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Hematopoietic and Lymphoid Cell Neoplasm+11 more
M.D. Anderson Cancer Center 8
Early research (Phase 1)Study completedNCT04430842
What this trial is testing

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Who this might be right for
AstrocytomaBrain CancerBrain Metastases+20 more
Quadriga Biosciences, Inc. 15
Testing effectiveness (Phase 2)Ended earlyNCT00121420
What this trial is testing

Study of Motexafin Gadolinium With Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patients With Brain Metastases

Who this might be right for
Neoplasm MetastasisBrain Neoplasms
Pharmacyclics LLC. 45
Testing effectiveness (Phase 2)UnknownNCT04001725
What this trial is testing

Efficacy of metfOrmin in PrevenTIng Glucocorticoid-induced Diabetes in Patients With Brain Metastases

Who this might be right for
Brain MetastasesMelanomaLung Cancer+1 more
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 110
Testing effectiveness (Phase 2)Looking for participantsNCT06163820
What this trial is testing

Bevacizumab and ICIs + hSRT in Symptomatic Melanoma Brain Metastases

Who this might be right for
Melanoma Brain Metastases
Melanoma and Skin Cancer Trials Limited 46
Testing effectiveness (Phase 2)Ended earlyNCT03903640
What this trial is testing

Optune Device - TT Field Plus Nivolumab and Ipilimumab for Melanoma With Brain Metastasis

Who this might be right for
Melanoma With Brain Metastasis
Washington University School of Medicine 2
Testing effectiveness (Phase 2)Study completedNCT03873818
What this trial is testing

Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Malignant Neoplasm in the BrainMetastatic Melanoma+1 more
M.D. Anderson Cancer Center 24
Testing effectiveness (Phase 2)Study completedNCT02308020
What this trial is testing

Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain

Who this might be right for
Breast CancerNon-small Cell Lung CancerMelanoma+1 more
Eli Lilly and Company 162
Testing effectiveness (Phase 2)Ended earlyNCT01721603
What this trial is testing

Dabrafenib and Trametinib With Radiosurgery in Melanoma Brain Mets

Who this might be right for
BRAFV600E Melanoma Patients
University of California, San Francisco 2
Not applicableEnded earlyNCT03698162
What this trial is testing

Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases

Who this might be right for
Brain MetastasesGlioma of BrainBrain Tumor+1 more
University of Southern California 15
Testing effectiveness (Phase 2)Looking for participantsNCT05704647
What this trial is testing

Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases

Who this might be right for
Melanoma (Skin)
M.D. Anderson Cancer Center 30
Testing effectiveness (Phase 2)Ended earlyNCT00550654
What this trial is testing

Conformal Radiation Therapy in Treating Patients With Metastatic Cancer Outside the Brain

Who this might be right for
Kidney CancerMelanoma (Skin)Metastatic Cancer+3 more
National Institutes of Health Clinical Center (CC) 1
Not applicableUnknownNCT05510466
What this trial is testing

Triple BRAFinh/MEKinh /antiPD1 Combined Therapy in Patients With BRAF Mutated Melanoma With Central Nervous System Metastasis

Who this might be right for
Metastatic Melanoma
University Hospital, Montpellier 18
Not applicableStudy completedNCT02058953
What this trial is testing

CNS and Extracranial Tumor Tissues, CSF, and Blood From Patients With Melanoma Brain Metastases

Who this might be right for
MelanomaBrain Metastases
University of Pittsburgh 7
Not applicableStudy completedNCT03520634
What this trial is testing

PD-L1 PET Imaging in Melanoma Patients

Who this might be right for
Melanoma
University Medical Center Groningen 10
Testing effectiveness (Phase 2)Ended earlyNCT02097732
What this trial is testing

Ipilimumab Induction in Patients With Melanoma Brain Metastases Receiving Stereotactic Radiosurgery

Who this might be right for
Metastatic MelanomaBrain Metastases
University of Michigan Rogel Cancer Center 4
Testing effectiveness (Phase 2)Study completedNCT00623766
What this trial is testing

Evaluation of Tumor Response to Ipilimumab in the Treatment of Melanoma With Brain Metastases

Who this might be right for
Melanoma
Bristol-Myers Squibb 99
Load More Results