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Results for “Melanoma of Unknown Primary”

27 trials

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Showing 20 of 27 results

Large-scale testing (Phase 3)Active Not RecruitingNCT01274338
What this trial is testing

Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery

Who this might be right for
Melanoma of Unknown PrimaryRecurrent MelanomaStage IIIB Cutaneous Melanoma AJCC v7+2 more
National Cancer Institute (NCI) 1,673
Very early researchEnded earlyNCT00499733
What this trial is testing

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

Who this might be right for
Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 19
Testing effectiveness (Phase 2)Active Not RecruitingNCT04708418
What this trial is testing

A Study Evaluating Whether Pembrolizumab Alone or in Combination With CMP-001 Improves Efficacy of Treatment in Patients With Operable Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Melanoma of Unknown PrimaryPathologic Stage IIIB Cutaneous Melanoma AJCC v8+3 more
National Cancer Institute (NCI) 60
Early research (Phase 1)Study completedNCT00014456
What this trial is testing

Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors

Who this might be right for
Bladder CancerBreast CancerCarcinoma of Unknown Primary+9 more
Dartmouth-Hitchcock Medical Center 35
Not applicableLooking for participantsNCT05461430
What this trial is testing

Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)

Who this might be right for
Pleural Effusion, MalignantAscites, MalignantCarcinoma+29 more
Travera Inc 200
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Early research (Phase 1)Active Not RecruitingNCT01366144
What this trial is testing

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

Who this might be right for
Breast CarcinomaCarcinoma of Unknown PrimaryEndometrial Carcinoma+11 more
National Cancer Institute (NCI) 94
Testing effectiveness (Phase 2)Study completedNCT00936221
What this trial is testing

Comparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma Patients

Who this might be right for
Melanoma
AstraZeneca 385
Not applicableLooking for participantsNCT03740503
What this trial is testing

Genomic Investigation of Unusual Responders

Who this might be right for
CancerBreast CancerNon-small Cell Lung Cancer+8 more
University Health Network, Toronto 100
Early research (Phase 1)Active Not RecruitingNCT05341349
What this trial is testing

Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Melanoma of Unknown PrimaryMetastatic Malignant Neoplasm in the Brain+4 more
Emory University 1
Testing effectiveness (Phase 2)Active Not RecruitingNCT02713269
What this trial is testing

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

Who this might be right for
Malignant Digestive System NeoplasmMetastatic Head and Neck CarcinomaMetastatic Kidney Carcinoma+10 more
M.D. Anderson Cancer Center 60
Testing effectiveness (Phase 2)Study completedNCT03033576
What this trial is testing

Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Melanoma of Unknown Primary+3 more
National Cancer Institute (NCI) 94
Testing effectiveness (Phase 2)Study completedNCT02129075
What this trial is testing

A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma

Who this might be right for
Cutaneous MelanomaMelanomaMelanoma of Unknown Primary+9 more
National Cancer Institute (NCI) 60
Testing effectiveness (Phase 2)Study completedNCT04133948
What this trial is testing

Multicenter Phase 1b Trial Testing the Neoadjuvant Combination of Domatinostat, Nivolumab and Ipilimumab in IFN-gamma Signature-low and IFN-gamma Signature-high RECIST 1.1-measurable Stage III Cutaneous or Unknown Primary Melanoma

Who this might be right for
Malignant Melanoma Stage III
The Netherlands Cancer Institute 44
Testing effectiveness (Phase 2)Active Not RecruitingNCT04802876
What this trial is testing

Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors

Who this might be right for
MSI-H Colorectal CancerMelanomaAnal Carcinoma+28 more
SOLTI Breast Cancer Research Group 184
Not applicableStudy completedNCT01624220
What this trial is testing

A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy

Who this might be right for
Spinal Tumor
M.D. Anderson Cancer Center 41
Testing effectiveness (Phase 2)Ended earlyNCT04221438
What this trial is testing

Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement

Who this might be right for
Melanoma of Unknown PrimaryMetastatic Malignant Neoplasm in Lymph NodePathologic Stage IIIB Cutaneous Melanoma AJCC v8+3 more
ECOG-ACRIN Cancer Research Group 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT04462406
What this trial is testing

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Who this might be right for
Advanced MelanomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+8 more
ECOG-ACRIN Cancer Research Group 150
Not applicableStudy completedNCT02966509
What this trial is testing

Engagement of Patients With Advanced Cancer

Who this might be right for
End of LifeAdvanced CancerLung Neoplasm+11 more
Stanford University 213
Early research (Phase 1)Study completedNCT00423254
What this trial is testing

Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.

Who this might be right for
OvarianMelanomaRenal+20 more
Mannkind Corporation 12
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