Not applicableApproved For MarketingNCT04729062What this trial is testingC3G/Primary IC-MPGN EAPWho this might be right forC3GIC-MPGNC3 Glomerulopathy+9 more Apellis Pharmaceuticals, Inc.
Large-scale testing (Phase 3)Looking for participantsNCT05755386What this trial is testingStudy of Efficacy and Safety of Iptacopan in Participants With IC-MPGNWho this might be right forIC-MPGN Novartis Pharmaceuticals 106
Not applicableStudy completedNCT03723512What this trial is testingNon-contrast Enhanced MRI in Patients With C3 Glomerulopathy (C3G) or Immune-complex Membranoproliferative Glomerulonephritis (IC-MPGN) Enrolled in the ACH471-205 StudyWho this might be right forC3 GlomerulonephritisC3 GlomerulopathyImmune Complex Membranoproliferative Glomerulonephritis+2 more Mario Negri Institute for Pharmacological Research 7
Early research (Phase 1)Study completedNCT01221181What this trial is testingEculizumab Therapy for Dense Deposit Disease and C3 NephropathyWho this might be right forDense Deposit DiseaseMembranoproliferative Glomerulonephritis Columbia University 6
Testing effectiveness (Phase 2)Ended earlyNCT03459443What this trial is testingA Proof of Concept Study for a 12 Month Treatment in Patients With C3G or IC-MPGN Treated With ACH-0144471Who this might be right forC3 GlomerulonephritisC3 GlomerulopathyImmune Complex Membranoproliferative Glomerulonephritis+2 more Alexion Pharmaceuticals, Inc. 22
Not applicableActive Not RecruitingNCT05985122What this trial is testingNew Analytic Tools for aHUS and C3G DiagnosisWho this might be right forHemolytic-Uremic SyndromeMembranoproliferative GlomerulonephritisHealthy Mario Negri Institute for Pharmacological Research 180
Testing effectiveness (Phase 2)Study completedNCT03124368What this trial is testingA Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGNWho this might be right forC3 GlomerulonephritisDense Deposit DiseaseC3 Glomerulopathy+2 more Alexion Pharmaceuticals, Inc. 6
Testing effectiveness (Phase 2)Looking for participantsNCT04183101What this trial is testingEvaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 GlomerulopathyWho this might be right forC3 GlomerulopathyMembranoproliferative GlomerulonephritisComplement Abnormality+2 more Region Skane 30
Testing effectiveness (Phase 2)Looking for participantsNCT07522099What this trial is testingChinese Adults With Kidney DiseaseWho this might be right forImmunoglobulin A Nephropathy (IgAN)Complement 3 Glomerulopathy (C3G)IC-MPGN ADARx Pharmaceuticals, Inc. 30
Testing effectiveness (Phase 2)Study completedNCT03301467What this trial is testingControlled Trial Evaluating Avacopan in C3 GlomerulopathyWho this might be right forC3 Glomerulopathy (C3G) Amgen 57
Testing effectiveness (Phase 2)Study completedNCT02093533What this trial is testingEculizumab in Primary MPGNWho this might be right forMembranoproliferative Glomerulonephritis Mario Negri Institute for Pharmacological Research 10
Testing effectiveness (Phase 2)Study completedNCT03369236What this trial is testingA Proof-of-Concept Study of Danicopan for 6 Months of Treatment in Participants With C3 Glomerulopathy (C3G)Who this might be right forC3 GlomerulopathyC3 GlomerulonephritisDense Deposit Disease Alexion Pharmaceuticals, Inc. 13
Post-approval studies (Phase 4)Looking for participantsNCT07746895What this trial is testingReal-World Effectiveness and Safety of Pegcetacoplan in Patients With C3G or IC-MPG: A Multi-Country StudyWho this might be right forC3 Glomerulopathy (C3G)Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN) Swedish Orphan Biovitrum 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT06786338What this trial is testingSGB-9768 in Patients With Complement-mediated Kidney DiseasesWho this might be right forIgA Nephropathy (IgAN)C3 GlomerulopathyIC-MPGN Suzhou Sanegene Bio Inc. 45
Testing effectiveness (Phase 2)Study completedNCT04572854What this trial is testingStudy Assessing the Safety and Efficacy of Pegcetacoplan in Post-Transplant Recurrence of C3G or IC-MPGNWho this might be right forC3GIC-MPGNRenal Transplant+9 more Apellis Pharmaceuticals, Inc. 13
Large-scale testing (Phase 3)Active Not RecruitingNCT03747159What this trial is testingSynergetic B-cell Immunomodulation in SLE - 2nd Study.Who this might be right forLupus Erythematosus, Systemic Leiden University Medical Center 70
Testing effectiveness (Phase 2)Study completedNCT03095118What this trial is testingDaratumumab in Treatment of PGNMID and C3 GNWho this might be right forMembranoproliferative Glomerulonephritis Fernando Fervenza 12
Large-scale testing (Phase 3)Study completedNCT05067127What this trial is testingPhase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative GlomerulonephritisWho this might be right forC3GIC-MPGNC3 Glomerulopathy+9 more Apellis Pharmaceuticals, Inc. 124
Not applicableLooking for participantsNCT06065852What this trial is testingNational Registry of Rare Kidney DiseasesWho this might be right forAdenine Phosphoribosyltransferase DeficiencyAH AmyloidosisAHL Amyloidosis+81 more UK Kidney Association 35,000
Large-scale testing (Phase 3)Active Not RecruitingNCT05809531What this trial is testingAn Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative GlomerulonephritisWho this might be right forC3GIC-MPGNC3 Glomerulopathy+9 more Apellis Pharmaceuticals, Inc. 100