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Results for “Membranoproliferative Glomerulonephritis (MPGN)”

25 trials

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Showing 20 of 25 results

Large-scale testing (Phase 3)Study completedNCT05067127
What this trial is testing

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

Who this might be right for
C3GIC-MPGNC3 Glomerulopathy+9 more
Apellis Pharmaceuticals, Inc. 124
Not applicableActive Not RecruitingNCT05985122
What this trial is testing

New Analytic Tools for aHUS and C3G Diagnosis

Who this might be right for
Hemolytic-Uremic SyndromeMembranoproliferative GlomerulonephritisHealthy
Mario Negri Institute for Pharmacological Research 180
Testing effectiveness (Phase 2)Looking for participantsNCT04183101
What this trial is testing

Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy

Who this might be right for
C3 GlomerulopathyMembranoproliferative GlomerulonephritisComplement Abnormality+2 more
Region Skane 30
Testing effectiveness (Phase 2)Study completedNCT03301467
What this trial is testing

Controlled Trial Evaluating Avacopan in C3 Glomerulopathy

Who this might be right for
C3 Glomerulopathy (C3G)
Amgen 57
Testing effectiveness (Phase 2)Looking for participantsNCT07522099
What this trial is testing

Chinese Adults With Kidney Disease

Who this might be right for
Immunoglobulin A Nephropathy (IgAN)Complement 3 Glomerulopathy (C3G)IC-MPGN
ADARx Pharmaceuticals, Inc. 30
Large-scale testing (Phase 3)UnknownNCT03180723
What this trial is testing

Effect of Rituximab in Treatment of Membranoproliferative Glomerulonephritis

Who this might be right for
Membranoproliferative Glomerulonephritis
Assiut University 30
Large-scale testing (Phase 3)Active Not RecruitingNCT03747159
What this trial is testing

Synergetic B-cell Immunomodulation in SLE - 2nd Study.

Who this might be right for
Lupus Erythematosus, Systemic
Leiden University Medical Center 70
Large-scale testing (Phase 3)Active Not RecruitingNCT05809531
What this trial is testing

An Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

Who this might be right for
C3GIC-MPGNC3 Glomerulopathy+9 more
Apellis Pharmaceuticals, Inc. 100
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06786338
What this trial is testing

SGB-9768 in Patients with Complement-mediated Kidney Diseases

Who this might be right for
IgA Nephropathy (IgAN)C3 GlomerulopathyIC-MPGN
Suzhou Sanegene Bio Inc. 38
Large-scale testing (Phase 3)Looking for participantsNCT05755386
What this trial is testing

Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

Who this might be right for
IC-MPGN
Novartis Pharmaceuticals 106
Testing effectiveness (Phase 2)Study completedNCT03124368
What this trial is testing

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

Who this might be right for
C3 GlomerulonephritisDense Deposit DiseaseC3 Glomerulopathy+2 more
Alexion Pharmaceuticals, Inc. 6
Not applicableLooking for participantsNCT06065852
What this trial is testing

National Registry of Rare Kidney Diseases

Who this might be right for
Adenine Phosphoribosyltransferase DeficiencyAH AmyloidosisAHL Amyloidosis+81 more
UK Kidney Association 35,000
Testing effectiveness (Phase 2)Ended earlyNCT03459443
What this trial is testing

A Proof of Concept Study for a 12 Month Treatment in Patients With C3G or IC-MPGN Treated With ACH-0144471

Who this might be right for
C3 GlomerulonephritisC3 GlomerulopathyImmune Complex Membranoproliferative Glomerulonephritis+2 more
Alexion Pharmaceuticals, Inc. 22
Testing effectiveness (Phase 2)Study completedNCT03095118
What this trial is testing

Daratumumab in Treatment of PGNMID and C3 GN

Who this might be right for
Membranoproliferative Glomerulonephritis
Fernando Fervenza 12
Early research (Phase 1)Ended earlyNCT01791686
What this trial is testing

Clinical Trial of CDX-1135 in Pediatric and Adult Patients With Dense Deposit Disease

Who this might be right for
Dense Deposit DiseaseMembranoproliferative Glomerulonephritis Type IIC3 Glomerulonephritis
Celldex Therapeutics 1
Early research (Phase 1)Study completedNCT01221181
What this trial is testing

Eculizumab Therapy for Dense Deposit Disease and C3 Nephropathy

Who this might be right for
Dense Deposit DiseaseMembranoproliferative Glomerulonephritis
Columbia University 6
Testing effectiveness (Phase 2)Study completedNCT03369236
What this trial is testing

A Proof-of-Concept Study of Danicopan for 6 Months of Treatment in Participants With C3 Glomerulopathy (C3G)

Who this might be right for
C3 GlomerulopathyC3 GlomerulonephritisDense Deposit Disease
Alexion Pharmaceuticals, Inc. 13
Not applicableLooking for participantsNCT05996731
What this trial is testing

Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases

Who this might be right for
Atypical Hemolytic Uremic SyndromeMembranoproliferative GlomerulonephritisAutosomal Dominant Polycystic Kidney+1 more
Mario Negri Institute for Pharmacological Research 105
Not applicableStudy completedNCT03723512
What this trial is testing

Non-contrast Enhanced MRI in Patients With C3 Glomerulopathy (C3G) or Immune-complex Membranoproliferative Glomerulonephritis (IC-MPGN) Enrolled in the ACH471-205 Study

Who this might be right for
C3 GlomerulonephritisC3 GlomerulopathyImmune Complex Membranoproliferative Glomerulonephritis+2 more
Mario Negri Institute for Pharmacological Research 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT04572854
What this trial is testing

Study Assessing the Safety and Efficacy of Pegcetacoplan in Post-Transplant Recurrence of C3G or IC-MPGN

Who this might be right for
C3GIC-MPGNRenal Transplant+9 more
Apellis Pharmaceuticals, Inc. 13
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