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Results for “Merkel Cell Carcinoma, Stage IV”

28 trials

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Showing 20 of 28 results

Early research (Phase 1)WithdrawnNCT02831179
What this trial is testing

Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor

Who this might be right for
Functional Pancreatic Neuroendocrine TumorMalignant SomatostatinomaMerkel Cell Carcinoma+26 more
Vanderbilt-Ingram Cancer Center
Early research (Phase 1)Active Not RecruitingNCT04616248
What this trial is testing

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaPrognostic Stage IV Breast Cancer AJCC v8+10 more
University of Southern California 14
Testing effectiveness (Phase 2)Looking for participantsNCT05896839
What this trial is testing

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+10 more
National Cancer Institute (NCI) 16
Testing effectiveness (Phase 2)Study completedNCT02267603
What this trial is testing

Pembrolizumab in Treating Patients With Advanced Merkel Cell Cancer

Who this might be right for
Recurrent Merkel Cell CarcinomaStage III Merkel Cell Carcinoma AJCC v7Stage IIIA Merkel Cell Carcinoma AJCC v7+2 more
National Cancer Institute (NCI) 50
Early research (Phase 1)Study completedNCT01155258
What this trial is testing

Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors

Who this might be right for
Extensive Stage Small Cell Lung CancerHereditary ParagangliomaMale Breast Cancer+45 more
University of Southern California 19
Testing effectiveness (Phase 2)Study completedNCT03304639
What this trial is testing

Testing the Addition of Radiation Therapy to Immunotherapy for Merkel Cell Carcinoma

Who this might be right for
Advanced Merkel Cell CarcinomaClinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8+5 more
National Cancer Institute (NCI) 9
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07472322
What this trial is testing

ASTX727 & Retifanlimab-dlwr for Advanced Merkel Cell After Progression on Anti-PD-(L)1

Who this might be right for
Merkel Cell CarcinomaMerkel Cell Carcinoma, Stage IIIMerkel Cell Carcinoma, Stage IV
University of Wisconsin, Madison 31
Early research (Phase 1)Ended earlyNCT00002947
What this trial is testing

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Langerhans Cell HistiocytosisGastrointestinal Carcinoid Tumor+9 more
Yale University 35
Testing effectiveness (Phase 2)Ended earlyNCT01758458
What this trial is testing

Viral Oncoprotein Targeted Autologous T Cell Therapy for Merkel Cell Carcinoma

Who this might be right for
Recurrent Merkel Cell CarcinomaStage IV Merkel Cell Carcinoma
Fred Hutchinson Cancer Center 4
Testing effectiveness (Phase 2)Ended earlyNCT04902040
What this trial is testing

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Who this might be right for
Advanced Bladder CarcinomaAdvanced Lung Non-Small Cell CarcinomaAdvanced Malignant Solid Neoplasm+32 more
M.D. Anderson Cancer Center 19
Testing effectiveness (Phase 2)Study completedNCT00079131
What this trial is testing

Oblimersen in Treating Patients With Merkel Cell Carcinoma

Who this might be right for
Recurrent Neuroendocrine Carcinoma of the SkinStage I Neuroendocrine Carcinoma of the SkinStage II Neuroendocrine Carcinoma of the Skin+2 more
National Cancer Institute (NCI) 37
Not applicableLooking for participantsNCT07215988
What this trial is testing

Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study

Who this might be right for
Clinical Stage II Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8+5 more
Ohio State University Comprehensive Cancer Center 70
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+97 more
Mayo Clinic 132
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07576725
What this trial is testing

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+40 more
Fred Hutchinson Cancer Center 50
Early research (Phase 1)Looking for participantsNCT06444815
What this trial is testing

VET3-TGI in Patients With Solid Tumors

Who this might be right for
Solid Tumor, AdultMicrosatellite Stable Colorectal CancerHead and Neck Squamous Cell Carcinoma+10 more
KaliVir Immunotherapeutics 60
Testing effectiveness (Phase 2)Study completedNCT02643303
What this trial is testing

Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers

Who this might be right for
Head and Neck Squamous Cell CarcinomaBreast CancerSarcoma+8 more
Ludwig Institute for Cancer Research 58
Testing effectiveness (Phase 2)Active Not RecruitingNCT05947500
What this trial is testing

Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial

Who this might be right for
Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8Locally Advanced Merkel Cell Carcinoma+3 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Ended earlyNCT03747484
What this trial is testing

Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer

Who this might be right for
Other Skin
Fred Hutchinson Cancer Center 7
Not applicableAvailableNCT04853602
What this trial is testing

IFx-Hu2.0 Expanded Access Program

Who this might be right for
Cutaneous Melanoma, Stage IIICutaneous Melanoma, Stage IVMerkel Cell Carcinoma+1 more
TuHURA Biosciences, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT02465957
What this trial is testing

QUILT-3.009: Patients With Stage III (IIIB) or Stage (IV) Merkel Cell Carcinoma (MCC)

Who this might be right for
Stage IIIB Merkel Cell CarcinomaStage IV Merkel Cell Carcinoma
ImmunityBio, Inc. 7
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