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Results for “Mesothelin (Msln)”

107 trials

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Showing 20 of 107 results

Early research (Phase 1)Study completedNCT01897415
What this trial is testing

Autologous Redirected RNA Meso CAR T Cells for Pancreatic Cancer

Who this might be right for
Subjects With Metastatic Pancreatic Ductal Adenocarcinoma (PDA)
University of Pennsylvania 16
Not applicableUnknownNCT00155740
What this trial is testing

Mesothelin as a New Tumor Marker for Ovarian Cancer

Who this might be right for
Ovarian Cancer
National Taiwan University Hospital 250
Early research (Phase 1)Study completedNCT00066651
What this trial is testing

Immunotoxin Therapy in Treating Patients With Advanced Solid Tumors

Who this might be right for
Cervical CancerFallopian Tube CancerHead and Neck Cancer+5 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT06051695
What this trial is testing

Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNSCLC+17 more
A2 Biotherapeutics Inc. 474
Testing effectiveness (Phase 2)Ended earlyNCT01583686
What this trial is testing

CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer

Who this might be right for
Cervical CancerPancreatic CancerOvarian Cancer+2 more
National Cancer Institute (NCI) 15
Early research (Phase 1)UnknownNCT02930993
What this trial is testing

Anti-mesothelin CAR T Cells for Patients With Recurrent or Metastatic Malignant Tumors

Who this might be right for
Mesothelin Positive Tumors
China Meitan General Hospital 20
Testing effectiveness (Phase 2)UnknownNCT03356808
What this trial is testing

Antigen-specific T Cells Against Lung Cancer

Who this might be right for
Lung Cancer
Shenzhen Geno-Immune Medical Institute 20
Not applicableUnknownNCT00173394
What this trial is testing

The Assessment of Mesothelin Antigen Specific Immunologic Assays in Ovarian Cancer Patients

Who this might be right for
Ovarian Cancer
National Taiwan University Hospital 250
Early research (Phase 1)Study completedNCT02696642
What this trial is testing

Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment

Who this might be right for
Neoplasms
Bayer 54
Not applicableStudy completedNCT05372692
What this trial is testing

Study of LD013 in Subjects With Refractory or Relapsed Mesothelin -Positive Ovarian Cancer

Who this might be right for
Ovarian Cancer
Weijia Fang, MD 3
Very early researchLooking for participantsNCT05166070
What this trial is testing

An Exploratory Clinical Study of RD133 in Subjects With Relapsed or Refractory MSLN-Positive Solid Tumors

Who this might be right for
Solid Tumor
The First Affiliated Hospital with Nanjing Medical University 24
Testing effectiveness (Phase 2)Looking for participantsNCT07083323
What this trial is testing

A Phase I/II Study of HY05350 in Mesothelin(MSLN)-Positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Sichuan Huiyu Pharmaceutical Co., Ltd 262
Testing effectiveness (Phase 2)Study completedNCT03023722
What this trial is testing

Phase II Anetumab Ravtansine in Pre-treated Mesothelin-expressing Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Yale University 18
Early research (Phase 1)Study completedNCT01439152
What this trial is testing

Phase I Study to Determine the Maximum Tolerable Dose of BAY94-9343 in Patients With Advanced Solid Tumors.

Who this might be right for
Oncology
Bayer 148
Early research (Phase 1)UnknownNCT03545815
What this trial is testing

Study of CRISPR-Cas9 Mediated PD-1 and TCR Gene-knocked Out Mesothelin-directed CAR-T Cells in Patients With Mesothelin Positive Multiple Solid Tumors.

Who this might be right for
Solid Tumor, Adult
Chinese PLA General Hospital 10
Early research (Phase 1)WithdrawnNCT00024674
What this trial is testing

Study of SS1(dsFv)-PE38 (SS1P) Anti-Mesothelin Immunotoxin in Advanced Malignancies: Continuous Infusion for 10 Days

Who this might be right for
Neoplasms
INSYS Therapeutics Inc
Early research (Phase 1)Study completedNCT02751918
What this trial is testing

Phase Ib Study of Anetumab Ravtansine in Combination With Pegylated Liposomal Doxorubicin in Patients With Recurrent Mesothelin-expressing Platinum-resistant Cancer

Who this might be right for
Ovarian Neoplasms
Bayer 65
Early research (Phase 1)Study completedNCT06255665
What this trial is testing

JNJ-79032421 Targeting Mesothelin for Advanced Stage Solid Tumors

Who this might be right for
Advanced Stage Solid Tumors
Janssen Research & Development, LLC 35
Very early researchEnded earlyNCT01413451
What this trial is testing

Amatuximab for High Mesothelin Cancers

Who this might be right for
Carcinoma, Pancreatic DuctalMesotheliomaOvarian Neoplasms+1 more
National Cancer Institute (NCI) 7
Early research (Phase 1)Study completedNCT02884726
What this trial is testing

Phase 1 Study of Mesothelin-ADC

Who this might be right for
Advanced Cancer
Bristol-Myers Squibb 8
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