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Results for “Mesothelin (Msln)”

121 trials

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Showing 20 of 121 results

Early research (Phase 1)Study completedNCT02639091
What this trial is testing

Phase Ib Study of Anetumab Ravtansine in Combination With Pemetrexed and Cisplatin in Mesothelin-expressing Solid Tumors

Who this might be right for
Medical Oncology
Bayer 36
Not applicableLooking for participantsNCT01950572
What this trial is testing

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

Who this might be right for
ThymomaStomach NeoplasmsPancreatic Neoplasms+3 more
National Cancer Institute (NCI) 1,000
Early research (Phase 1)Study completedNCT02696642
What this trial is testing

Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment

Who this might be right for
Neoplasms
Bayer 54
Testing effectiveness (Phase 2)Study completedNCT02610140
What this trial is testing

Phase II Anetumab Ravtansine as 2nd Line Treatment for Malignant Pleural Mesothelioma (MPM)

Who this might be right for
Mesothelioma
Bayer 248
Early research (Phase 1)Ended earlyNCT04809766
What this trial is testing

Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
Metastatic Pancreatic Ductal AdenocarcinomaStage IV Pancreatic Cancer AJCC v8
Fred Hutchinson Cancer Center 9
Testing effectiveness (Phase 2)Looking for participantsNCT07523529
What this trial is testing

Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors

Who this might be right for
Advanced UnresectableMetastatic
Beijing Biotech 72
Testing effectiveness (Phase 2)Active Not RecruitingNCT03126630
What this trial is testing

Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma

Who this might be right for
Pleural Malignant Mesothelioma
National Cancer Institute (NCI) 49
Testing effectiveness (Phase 2)Looking for participantsNCT07627711
What this trial is testing

Dual-Target CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma

Who this might be right for
Pancreatic Ductal Adenocarcinoma (PDAC)Unresectable Locally AdvancedMetastatic Disease
Beijing Biotech 42
Early research (Phase 1)Looking for participantsNCT06196294
What this trial is testing

GPC3/Mesothelin-CAR-γδT Cells Against Cancers

Who this might be right for
Pancreas CancerLung CancerLiver Cancer+3 more
Second Affiliated Hospital of Guangzhou Medical University 30
Early research (Phase 1)Study completedNCT02824042
What this trial is testing

Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole

Who this might be right for
Medical Oncology
Bayer 63
Early research (Phase 1)Looking for participantsNCT03198052
What this trial is testing

GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers

Who this might be right for
Lung CancerCancerImmunotherapy+1 more
Second Affiliated Hospital of Guangzhou Medical University 30
Early research (Phase 1)Study completedNCT00066651
What this trial is testing

Immunotoxin Therapy in Treating Patients With Advanced Solid Tumors

Who this might be right for
Cervical CancerFallopian Tube CancerHead and Neck Cancer+5 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT02004262
What this trial is testing

Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting

Who this might be right for
2nd-line, 3rd-line and Greater Metastatic Pancreatic Cancer
Aduro Biotech, Inc. 303
Early research (Phase 1)Looking for participantsNCT06756035
What this trial is testing

CT-95 in Advanced Cancers Associated With Mesothelin Expression

Who this might be right for
Mesothelin-Expressing TumorsEpithelial Ovarian CancerMalignant Pleural Mesothelioma, Advanced+8 more
Context Therapeutics Inc. 70
Not applicableLooking for participantsNCT06717022
What this trial is testing

A Clinical Study of CHT102 in Mesothelin Positive Advanced Solid Tumors

Who this might be right for
Mesothelin Positive Tumors
Tianjin Medical University Cancer Institute and Hospital 24
Early research (Phase 1)WithdrawnNCT05375825
What this trial is testing

Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin

Who this might be right for
Malignant Pleural Mesotheliomas (Mpm)Malignant Pleural Effusions (Mpe)Epithelial Tumors, Malignant+2 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT03054298
What this trial is testing

CAR T Cells in Mesothelin Expressing Cancers

Who this might be right for
Lung AdenocarcinomaOvarian CancerPeritoneal Carcinoma+3 more
University of Pennsylvania 65
Early research (Phase 1)WithdrawnNCT00024687
What this trial is testing

Study of SS1(dsFv)-PE38 (SS1P) Anti-Mesothelin Immunotoxin in Advanced Malignancies: IV Infusion QOD x Six Doses

Who this might be right for
Neoplasms
INSYS Therapeutics Inc
Early research (Phase 1)Study completedNCT01897415
What this trial is testing

Autologous Redirected RNA Meso CAR T Cells for Pancreatic Cancer

Who this might be right for
Subjects With Metastatic Pancreatic Ductal Adenocarcinoma (PDA)
University of Pennsylvania 16
Early research (Phase 1)Study completedNCT02798536
What this trial is testing

Mesothelin-Targeted Immunotoxin LMB-100 in People With Malignant Mesothelioma

Who this might be right for
Mesothelioma
National Cancer Institute (NCI) 21
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