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Results for “Mesothelin Positive Tumors”

59 trials

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Showing 20 of 59 results

Testing effectiveness (Phase 2)Study completedNCT02810418
What this trial is testing

Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination With Nab-Paclitaxel in People With Previously Treated Metastatic and/or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors

Who this might be right for
NeoplasmsPancreatic Neoplasms
National Cancer Institute (NCI) 40
Early research (Phase 1)Looking for participantsNCT06885697
What this trial is testing

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Who this might be right for
MesotheliomaNeoplasmsStomach Neoplasms+5 more
National Cancer Institute (NCI) 100
Early research (Phase 1)UnknownNCT05848999
What this trial is testing

UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Mesothelin-positive Advanced Malignant Solid Tumors
Zhejiang University 87
Early research (Phase 1)Looking for participantsNCT05410717
What this trial is testing

CLDN6/GPC3/Mesothelin/AXL-CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
Stage IV Ovarian CancerTestis Cancer, RefractoryEndometrial Cancer Recurrent+1 more
Second Affiliated Hospital of Guangzhou Medical University 200
Early research (Phase 1)UnknownNCT06256055
What this trial is testing

Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Malignant MesotheliomaColorectal CancerBile Duct Cancer+4 more
UTC Therapeutics Inc. 24
Testing effectiveness (Phase 2)UnknownNCT05944185
What this trial is testing

Phase I/II Study of αPD1-MSLN-CAR T Cells in MSLN-positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Shanghai Cell Therapy Group Co.,Ltd 42
Very early researchUnknownNCT04503980
What this trial is testing

ΑPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors

Who this might be right for
Colorectal CancerOvarian Cancer
Shanghai Cell Therapy Group Co.,Ltd 10
Not applicableLooking for participantsNCT06717022
What this trial is testing

A Clinical Study of CHT102 in Mesothelin Positive Advanced Solid Tumors

Who this might be right for
Mesothelin Positive Tumors
Tianjin Medical University Cancer Institute and Hospital 24
Early research (Phase 1)Ended earlyNCT05623488
What this trial is testing

CAR T Cells in Mesothelin-Expressing Breast Cancer

Who this might be right for
Breast Cancer
University of Pennsylvania 2
Early research (Phase 1)Active Not RecruitingNCT02792114
What this trial is testing

T-Cell Therapy for Advanced Breast Cancer

Who this might be right for
Breast CancerMetastatic HER2-negative Breast
Memorial Sloan Kettering Cancer Center 186
Early research (Phase 1)Looking for participantsNCT05568680
What this trial is testing

SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

Who this might be right for
Ovarian CancerCholangiocarcinoma RecurrentMesothelioma, Malignant
Verismo Therapeutics 42
Early research (Phase 1)UnknownNCT03545815
What this trial is testing

Study of CRISPR-Cas9 Mediated PD-1 and TCR Gene-knocked Out Mesothelin-directed CAR-T Cells in Patients With Mesothelin Positive Multiple Solid Tumors.

Who this might be right for
Solid Tumor, Adult
Chinese PLA General Hospital 10
Testing effectiveness (Phase 2)Looking for participantsNCT07083323
What this trial is testing

A Phase I/II Study of HY05350 in Mesothelin(MSLN)-Positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Sichuan Huiyu Pharmaceutical Co., Ltd 262
Early research (Phase 1)Study completedNCT04034238
What this trial is testing

Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors

Who this might be right for
Neoplasms With Mesothelin ExpressionEpithelioid MesotheliomaCholangiocarcinoma, Extrahepatic+1 more
National Cancer Institute (NCI) 19
Testing effectiveness (Phase 2)Active Not RecruitingNCT03907852
What this trial is testing

Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer

Who this might be right for
MesotheliomaMesothelioma, MalignantMesothelioma; Pleura+8 more
TCR2 Therapeutics 57
Early research (Phase 1)Study completedNCT00325494
What this trial is testing

MORAb-009 in Subjects With Pancreatic Cancer, Mesothelioma, or Certain Types of Ovarian or Lung Cancer

Who this might be right for
Pancreatic CancerMesotheliomaOvarian Cancer+1 more
Morphotek 24
Early research (Phase 1)Ended earlyNCT05164666
What this trial is testing

TAK-103 in Adult With Solid Tumors

Who this might be right for
Solid Tumors
Takeda 2
Testing effectiveness (Phase 2)UnknownNCT03030001
What this trial is testing

PD-1 Antibody Expressing CAR T Cells for Mesothelin Positive Advanced Malignancies

Who this might be right for
Solid Tumor, AdultAdvanced Cancer
Ningbo Cancer Hospital 40
Early research (Phase 1)Study completedNCT01018784
What this trial is testing

MORAb-009 in Patients With Solid Tumor

Who this might be right for
CancerMesothelin-positive
Eisai Co., Ltd. 17
Very early researchLooking for participantsNCT05166070
What this trial is testing

An Exploratory Clinical Study of RD133 in Subjects With Relapsed or Refractory MSLN-Positive Solid Tumors

Who this might be right for
Solid Tumor
The First Affiliated Hospital with Nanjing Medical University 24
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