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Results for “Mesothelin-expressing Advanced Cancers”

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Showing 17 of 0 results

Early research (Phase 1)Ended earlyNCT03455556
What this trial is testing

Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer

Who this might be right for
Mesothelin PositiveStage III Non-Small Cell Lung Cancer AJCC v7Stage IIIA Non-Small Cell Lung Cancer AJCC v7+2 more
Mayo Clinic 1
Early research (Phase 1)Ended earlyNCT02317419
What this trial is testing

RO6927005 Either As Monotherapy (Part A) or in Combination With Gemcitabine and Nab-Paclitaxel (Part B) to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Clinical Activity in Patients With Mesothelin-positive Metastatic and/or Locally Advanced Malignant Solid Tumors

Who this might be right for
Cancer
Hoffmann-La Roche 15
Early research (Phase 1)Study completedNCT04034238
What this trial is testing

Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors

Who this might be right for
Neoplasms With Mesothelin ExpressionEpithelioid MesotheliomaCholangiocarcinoma, Extrahepatic+1 more
National Cancer Institute (NCI) 19
Testing effectiveness (Phase 2)Looking for participantsNCT06051695
What this trial is testing

Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNSCLC+17 more
A2 Biotherapeutics Inc. 474
Testing effectiveness (Phase 2)Study completedNCT02810418
What this trial is testing

Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination With Nab-Paclitaxel in People With Previously Treated Metastatic and/or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors

Who this might be right for
NeoplasmsPancreatic Neoplasms
National Cancer Institute (NCI) 40
Early research (Phase 1)Active Not RecruitingNCT03816358
What this trial is testing

Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer

Who this might be right for
Pancreatic AdenocarcinomaStage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8+1 more
National Cancer Institute (NCI) 74
Early research (Phase 1)UnknownNCT05089266
What this trial is testing

Study of αPD1-MSLN-CAR T Cells to Evaluate the Safety, Tolerability, and Effectiveness for Patients With MSLN-positive Advanced Solid Tumors

Who this might be right for
Colorectal Cancer
Shanghai Cell Therapy Group Co.,Ltd 30
Testing effectiveness (Phase 2)UnknownNCT03615313
What this trial is testing

PD-1 Antibody Expressing mesoCAR-T Cells for Mesothelin Positive Advanced Solid Tumor

Who this might be right for
Advanced Solid Tumor
Shanghai Cell Therapy Research Institute 50
Early research (Phase 1)Study completedNCT02824042
What this trial is testing

Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole

Who this might be right for
Medical Oncology
Bayer 63
Testing effectiveness (Phase 2)UnknownNCT05944185
What this trial is testing

Phase I/II Study of αPD1-MSLN-CAR T Cells in MSLN-positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Shanghai Cell Therapy Group Co.,Ltd 42
Early research (Phase 1)Ended earlyNCT05164666
What this trial is testing

TAK-103 in Adult With Solid Tumors

Who this might be right for
Solid Tumors
Takeda 2
Early research (Phase 1)Active Not RecruitingNCT02792114
What this trial is testing

T-Cell Therapy for Advanced Breast Cancer

Who this might be right for
Breast CancerMetastatic HER2-negative Breast
Memorial Sloan Kettering Cancer Center 186
Early research (Phase 1)Looking for participantsNCT06760364
What this trial is testing

A Clinical Study of CHT102 in MSLN-Positive Advanced Pancreatic Cancer

Who this might be right for
Advanced Pancreatic Cancers
Tianjin Medical University Cancer Institute and Hospital 21
Testing effectiveness (Phase 2)UnknownNCT03182803
What this trial is testing

CTLA-4 and PD-1 Antibodies Expressing Mesothelin-CAR-T Cells for Mesothelin Positive Advanced Solid Tumor

Who this might be right for
Advanced Solid Tumor
Shanghai Cell Therapy Research Institute 40
Early research (Phase 1)Study completedNCT02696642
What this trial is testing

Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment

Who this might be right for
Neoplasms
Bayer 54
Early research (Phase 1)UnknownNCT05775666
What this trial is testing

UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Solid Tumor
Peking University 87
Early research (Phase 1)UnknownNCT05848999
What this trial is testing

UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Mesothelin-positive Advanced Malignant Solid Tumors
Zhejiang University 87