Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Metachromatic Leukodystrophy (MLD)”

51 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 51 results

Testing effectiveness (Phase 2)Study completedNCT03406962
What this trial is testing

MGTA-456 in Patients With Inherited Metabolic Disorders Undergoing Hematopoietic Stem Cell Transplantation (HSCT)

Who this might be right for
Inherited Metabolic Disorders (IMD)
Magenta Therapeutics, Inc. 8
Large-scale testing (Phase 3)Active Not RecruitingNCT04283227
What this trial is testing

OTL-200 in Patients With Late Juvenile Metachromatic Leukodystrophy (MLD)

Who this might be right for
Lysosomal Storage DiseasesMetachromatic Leukodystrophy
Orchard Therapeutics 6
Not applicableStudy completedNCT01325025
What this trial is testing

Imaging Study of the White Matter Lesions in Children With Metachromatic Leucodystrophy

Who this might be right for
Late Infantile Metachromatic Leukodystrophy
Assistance Publique - Hôpitaux de Paris 29
Testing effectiveness (Phase 2)Study completedNCT00383448
What this trial is testing

HSCT for High Risk Inherited Inborn Errors

Who this might be right for
AdrenoleukodystrophyMetachromatic LeukodystrophyGloboid Cell Leukodystrophy+6 more
Masonic Cancer Center, University of Minnesota 38
Not applicableNo Longer AvailableNCT02084121
What this trial is testing

Allogeneic Stem Cell Transplantation for the Treatment of Multiple Sclerosis (Compassionate Use)

Who this might be right for
Metachromatic Leukodystrophy
Talaris Therapeutics Inc.
Not applicableLooking for participantsNCT04880356
What this trial is testing

Longitudinal Study of Ultra-rare Inherited Metabolic and Degenerative Neurological Diseases.

Who this might be right for
Inherited DiseaseRare DiseasesMetabolic Disease+3 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 100
Not applicableWithdrawnNCT01536327
What this trial is testing

Biomarker for Metachromatic Leukodystrophy (BioMeta) Disease

Who this might be right for
Peripheral NeuropathyMuscle Weakness
CENTOGENE GmbH Rostock
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Early research (Phase 1)Study completedNCT01586455
What this trial is testing

Human Placental-Derived Stem Cell Transplantation

Who this might be right for
Mucopolysaccharidosis IMucopolysaccharidosis VIAdrenoleukodystrophy+13 more
New York Medical College 43
Not applicableNot Yet RecruitingNCT07046338
What this trial is testing

Lentiviral Hematopoietic Stem Cell Gene Therapy for MLD

Who this might be right for
Metachromatic Leukodystrophy (MLD)
Shenzhen Geno-Immune Medical Institute 10
Not applicableWithdrawnNCT05755568
What this trial is testing

Learn About Metachromatic Leukodystrophy (MLD) in Children in Spain

Who this might be right for
Metachromatic Leukodystrophy (MLD)
Takeda
Not applicableUnknownNCT04324775
What this trial is testing

Comparison of Acute Effect of Different Manual Techniques on Muscle Fascia Stiffness

Who this might be right for
Manual Lymphatic DrainageSwedish MassageMuscle Fascia Stiffness
Marmara University 30
Testing effectiveness (Phase 2)Study completedNCT01801709
What this trial is testing

Intracerebral Gene Therapy for Children With Early Onset Forms of Metachromatic Leukodystrophy

Who this might be right for
Metachromatic Leukodystrophy
Institut National de la Santé Et de la Recherche Médicale, France 5
Not applicableEnded earlyNCT04008849
What this trial is testing

A Follow-up Study in Patients With Inherited Metabolic Disorders (IMD) Who Underwent Hematopoietic Stem Cell Transplantation (HSCT) With MGTA-456

Who this might be right for
Inherited Metabolic Disorders (IMD)
Magenta Therapeutics, Inc. 3
Testing effectiveness (Phase 2)Ended earlyNCT00681811
What this trial is testing

Open-Label Extension Study of Recombinant Human Arylsulfatase A (HGT-1111) in Late Infantile MLD

Who this might be right for
Late Infantile Metachromatic Leukodystrophy
Shire 11
Testing effectiveness (Phase 2)Study completedNCT01510028
What this trial is testing

Multicenter Study of HGT-1110 Administered Intrathecally in Children With Metachromatic Leukodystrophy (MLD)

Who this might be right for
Metachromatic Leukodystrophy (MLD)
Shire 24
Not applicableNo Longer AvailableNCT02021266
What this trial is testing

Single Patient Expanded Access Protocol: Metabolic Boost

Who this might be right for
Metachromatic Leukodystrophy
Talaris Therapeutics Inc.
Not applicableNot Yet RecruitingNCT03725670
What this trial is testing

Direct Lentiviral Injection Gene Therapy for MLD

Who this might be right for
Metachromatic Leukodystrophy (MLD)
Shenzhen Geno-Immune Medical Institute 10
Not applicableEnrolling By InvitationNCT05368038
What this trial is testing

ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening Program

Who this might be right for
Acid Sphingomyelinase DeficiencyCeroid Lipofuscinosis, Neuronal, 2Cerebrotendinous Xanthomatosis+11 more
Albert Einstein College of Medicine 100,000
Testing effectiveness (Phase 2)Ended earlyNCT01372228
What this trial is testing

Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders

Who this might be right for
Hurler Syndrome (MPS I)Hurler-Scheie SyndromeHunter Syndrome (MPS II)+9 more
Talaris Therapeutics Inc. 3
Next Page