Early research (Phase 1)Study completedNCT02442414What this trial is testingKBP-5209 in Patients With Advanced Solid TumorsWho this might be right forAdvanced Solid Tumors Sihuan Pharmaceutical Holdings Group Ltd. 35
Post-approval studies (Phase 4)Active Not RecruitingNCT06282874What this trial is testingLorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal MetastasesWho this might be right forCarcinoma, Non-Small-Cell LungBrain MetastasesLeptomeningeal Metastasis Guangdong Association of Clinical Trials 41
Testing effectiveness (Phase 2)Active Not RecruitingNCT06007937What this trial is testingLorlatinib in Combination With Ramucirumab in People With Lung CancerWho this might be right forNon Small Cell Lung CancerMetastaticRecurrent Memorial Sloan Kettering Cancer Center 9
Testing effectiveness (Phase 2)Looking for participantsNCT07360743What this trial is testingImmunotherapy Without Chemotherapy for Advanced Lung Cancer Patients With High PD-L1 LevelsWho this might be right forNon Small Cell Lung Cancer (Squamous or Non Squamous) UNICANCER 275
Large-scale testing (Phase 3)Study completedNCT02352948What this trial is testingA Global Study to Assess the Effects of MEDI4736 (Durvalumab), Given as Monotherapy or in Combination With Tremelimumab Determined by PD-L1 Expression Versus Standard of Care in Patients With Locally Advanced or Metastatic Non Small Cell Lung CancerWho this might be right forNon - Small Cell Lung Cancer NSCLC AstraZeneca 597
Testing effectiveness (Phase 2)Study completedNCT04111705What this trial is testingLorlatinib After Failure of First-line Second-generation ALK Kinase Inhibitor in Patients With Advanced ALK-positive Non-small Cell Lung CancerWho this might be right forNon Small Cell Lung Cancer Metastatic Intergroupe Francophone de Cancerologie Thoracique 23
Early research (Phase 1)Active Not RecruitingNCT03611738What this trial is testingCeritinib Plus Docetaxel in ALK-Negative, EGFR WT Advanced NSCLCWho this might be right forNon-small Cell Lung CancerLung CancerNon-small Cell Lung Cancer Metastatic+3 more H. Lee Moffitt Cancer Center and Research Institute 21
Early research (Phase 1)Ended earlyNCT04849273What this trial is testingTPX-0131, a Novel Oral ALK Tyrosine Kinase Inhibitor, in Patients With ALK+ Advanced or Metastatic NSCLCWho this might be right forNon Small Cell Lung CancerNon-Small Cell Lung CancerNSCLC+3 more Turning Point Therapeutics, Inc. 11
Early research (Phase 1)Active Not RecruitingNCT04837716What this trial is testingEnsartinib, Carboplatin, Pemetrexed and Bevacizumab for the Treatment of Stage IIIC or IV or Recurrent ALK-Positive Non-small Cell Lung CancerWho this might be right forMetastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage IIIC Lung Cancer AJCC v8+3 more M.D. Anderson Cancer Center 12
Early research (Phase 1)Active Not RecruitingNCT04227028What this trial is testingBrigatinib and Bevacizumab for the Treatment of ALK-Rearranged Locally Advanced, Metastatic, or Recurrent NSCLCWho this might be right forLocally Advanced Lung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell Carcinoma+7 more City of Hope Medical Center 5