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Results for “Metastatic Anal Squamous Cell Carcinoma”

49 trials

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Showing 20 of 49 results

Testing effectiveness (Phase 2)UnknownNCT03944252
What this trial is testing

Cetuximab + Avelumab or Avelumab Alone for Unresectable, Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (SCCAC) Progressed After at Least One Line of Systemic Treatment (CARACAS)

Who this might be right for
Squamous Cell Anal Carcinoma
Gruppo Oncologico del Nord-Ovest 54
Testing effectiveness (Phase 2)Active Not RecruitingNCT02834013
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Who this might be right for
Acinar Cell CarcinomaAdenoid Cystic CarcinomaAdrenal Cortical Carcinoma+91 more
National Cancer Institute (NCI) 798
Testing effectiveness (Phase 2)Active Not RecruitingNCT03260023
What this trial is testing

Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers

Who this might be right for
HPV-Related CarcinomaHPV-Related Cervical CarcinomaHPV-Related Anal Squamous Cell Carcinoma+2 more
Transgene 143
Large-scale testing (Phase 3)Active Not RecruitingNCT04444921
What this trial is testing

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Who this might be right for
Anal Basaloid CarcinomaAnal Canal Cloacogenic CarcinomaMetastatic Anal Squamous Cell Carcinoma+4 more
National Cancer Institute (NCI) 205
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Early research (Phase 1)Study completedNCT00004074
What this trial is testing

Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu

Who this might be right for
Advanced Adult Primary Liver CancerAnaplastic Thyroid CancerBone Metastases+124 more
National Cancer Institute (NCI) 15
Early research (Phase 1)Study completedNCT03849469
What this trial is testing

XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors

Who this might be right for
MelanomaCervical CarcinomaPancreatic Carcinoma+20 more
Xencor, Inc. 78
Large-scale testing (Phase 3)Study completedNCT04472429
What this trial is testing

Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).

Who this might be right for
Squamous Cell Carcinoma of the Anal Canal
Incyte Corporation 308
Testing effectiveness (Phase 2)WithdrawnNCT04499352
What this trial is testing

Test BI 754091 Alone or in Combination With BI 836880 in People Who Have Advanced Anal Cancer

Who this might be right for
Anal Canal Squamous Cell Carcinoma
Boehringer Ingelheim
Early research (Phase 1)Ended earlyNCT02408861
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmAnal CarcinomaHIV Infection+7 more
National Cancer Institute (NCI) 79
Testing effectiveness (Phase 2)WithdrawnNCT04536922
What this trial is testing

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated or Viral Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab

Who this might be right for
Metastatic HPV-16 Positive Squamous Cell Anal Cancer
National Cancer Institute (NCI)
Early research (Phase 1)Ended earlyNCT04272034
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+15 more
Incyte Corporation 105
Early research (Phase 1)Looking for participantsNCT06270706
What this trial is testing

PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumor
Pliant Therapeutics, Inc. 124
Early research (Phase 1)Active Not RecruitingNCT05973487
What this trial is testing

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerCervical CancerNon-small Cell Carcinoma+18 more
TScan Therapeutics, Inc. 840
Not applicableUnknownNCT03896958
What this trial is testing

The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)

Who this might be right for
Cancer, All TypesCancer of LiverCancer of Stomach+42 more
SpeciCare 1,000
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07511023
What this trial is testing

Phase 2 Trial Of Sacituzumab Tirumotecan For Treatment Of Refractory Metastatic Or Unresectable Squamous Cell Carcinoma Of The Anus/Rectum

Who this might be right for
Phase 2Sacituzumab TirumotecanRefractory Metastatic+2 more
M.D. Anderson Cancer Center 20
Testing effectiveness (Phase 2)Study completedNCT02399813
What this trial is testing

Axalimogene Filolisbac (ADXS11-001) in Participants With Carcinoma of the Anorectal Canal

Who this might be right for
Anal CancerRectal Cancer
Advaxis, Inc. 36
Early research (Phase 1)Ended earlyNCT01249443
What this trial is testing

Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection

Who this might be right for
HIV InfectionRecurrent Anal CancerRecurrent Breast Cancer+31 more
AIDS Malignancy Consortium 17
Testing effectiveness (Phase 2)Study completedNCT04357873
What this trial is testing

Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations

Who this might be right for
Squamous Cell Lung CancerVulvar CancerPenile Cancer+3 more
UNICANCER 112
Early research (Phase 1)Study completedNCT00049296
What this trial is testing

Thalidomide and Docetaxel in Treating Patients With Advanced Cancer

Who this might be right for
Cancer
Case Comprehensive Cancer Center 26
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