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Results for “Metastatic Cancer or Locally Advanced”

2,863 trials

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Showing 20 of 2,863 results

Large-scale testing (Phase 3)Active Not RecruitingNCT04603807
What this trial is testing

Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Hoffmann-La Roche 217
Testing effectiveness (Phase 2)Study completedNCT03548467
What this trial is testing

Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Locally Advanced or Metastatic Solid Tumours
Nykode Therapeutics ASA 41
Early research (Phase 1)Not Yet RecruitingNCT07836036
What this trial is testing

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

Who this might be right for
Solid TumorRAS Mutation
Jiangsu Aosaikang Pharmaceutical Co., Ltd. 200
Early research (Phase 1)Ended earlyNCT00996892
What this trial is testing

Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Genentech, Inc. 178
Testing effectiveness (Phase 2)Ended earlyNCT00321308
What this trial is testing

Trial of Pemetrexed With or Without PF-3512676 in Advanced Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small Cell Lung
Pfizer 36
Early research (Phase 1)WithdrawnNCT05381935
What this trial is testing

ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
Elpiscience Biopharma, Ltd.
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Early research (Phase 1)Ended earlyNCT05573035
What this trial is testing

Investigate LYL845 in Adults With Solid Tumors

Who this might be right for
MelanomaNon-small Cell Lung CancerColorectal Cancer
Lyell Immunopharma, Inc. 39
Testing effectiveness (Phase 2)Study completedNCT00669591
What this trial is testing

A Safety and Efficacy Study of Bavituximab Plus Docetaxel in Patients With Advanced Breast Cancer

Who this might be right for
Breast Cancer
Peregrine Pharmaceuticals 46
Testing effectiveness (Phase 2)UnknownNCT05775874
What this trial is testing

Evaluate the Safety and Efficacy of AZD4547 Combination With Tislelizumab in Patients With mUC

Who this might be right for
Urothelial Carcinoma
Abbisko Therapeutics Co, Ltd 80
Testing effectiveness (Phase 2)Study completedNCT02810418
What this trial is testing

Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination With Nab-Paclitaxel in People With Previously Treated Metastatic and/or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors

Who this might be right for
NeoplasmsPancreatic Neoplasms
National Cancer Institute (NCI) 40
Early research (Phase 1)Study completedNCT01170897
What this trial is testing

Study of PEGPH20 With Initial Dexamethasone Premedication Given Intravenously to Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Halozyme Therapeutics 27
Testing effectiveness (Phase 2)Looking for participantsNCT07043972
What this trial is testing

Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Fox Chase Cancer Center 55
Testing effectiveness (Phase 2)Looking for participantsNCT07296341
What this trial is testing

HRS-4642 Combination With Other Antitumor Therapies in Patients With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Pancreatic Cancer With
Shanghai Hengrui Pharmaceutical Co., Ltd. 60
Testing effectiveness (Phase 2)Looking for participantsNCT06293651
What this trial is testing

Clinical Trial to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of DA-4505 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid Tumors
Dong-A ST Co., Ltd. 125
Early research (Phase 1)Ended earlyNCT05061537
What this trial is testing

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Who this might be right for
Renal Cell CancerMelanomaNon-Small-Cell Lung Cancer+7 more
Pfizer 13
Testing effectiveness (Phase 2)Study completedNCT03108131
What this trial is testing

Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors

Who this might be right for
Skin Squamous Cell CarcinomaAppendix AdenocarcinomaRare Lesion+9 more
M.D. Anderson Cancer Center 49
Testing effectiveness (Phase 2)Study completedNCT00098345
What this trial is testing

Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer

Who this might be right for
Thyroid Cancer
Genzyme, a Sanofi Company 40
Testing effectiveness (Phase 2)Ended earlyNCT05169437
What this trial is testing

Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors

Who this might be right for
Solid TumorBreast TumorColon Tumor, Malignant+9 more
Tempus AI 22
Large-scale testing (Phase 3)Study completedNCT03984214
What this trial is testing

Efficacy and Safety of Dronabinol in the Improvement of Chemotherapy-induced and Tumor-related Symptoms in Advanced Pancreatic Cancer

Who this might be right for
Pancreatic Cancer Non-resectableChemotherapy-induced Nausea and VomitingPancreatic Cancer Metastatic
Arbeitsgemeinschaft medikamentoese Tumortherapie 109
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