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Results for “Metastatic HER2-positive Breast Cancer With Brain Metastasis”

47 trials

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Showing 20 of 47 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04538742
What this trial is testing

A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
AstraZeneca 245
Not applicableUnknownNCT03617341
What this trial is testing

Brain Monitoring for High Risk of Brain Metastases in Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer With HER2 PositiveTriple Negative Breast Cancer
Yonsei University 200
Testing effectiveness (Phase 2)UnknownNCT04334330
What this trial is testing

Palbociclib, Trastuzumab,Pyrotinib and Fulvestrant Treatment in Patients With Brain Metastasis From ER/PR Positive, HER-2 Positive Breast Cancer: A Multi-center, Prospective Study in China

Who this might be right for
Breast CancerBrain Metastases
Sun Yat-sen University 34
Testing effectiveness (Phase 2)UnknownNCT03933982
What this trial is testing

Pyrotinib Plus Vinorelbine in Patients With Brain Metastases From HER2-positive Metastatic Breast Cancer

Who this might be right for
Breast CancerBrain Metastases
Chinese Academy of Medical Sciences 30
Large-scale testing (Phase 3)Looking for participantsNCT03418961
What this trial is testing

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

Who this might be right for
CardiotoxicityHER2/Neu PositiveMetastatic Malignant Neoplasm in the Brain+2 more
SWOG Cancer Research Network 491
Testing effectiveness (Phase 2)Study completedNCT02614794
What this trial is testing

Tucatinib vs. Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer

Who this might be right for
HER2 Positive Breast Cancer
Seagen Inc. 612
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06797622
What this trial is testing

Heterogeneity of 68Ga-FAPI Uptake As Imaging Biomarker in T-DXd Treatment for Brain Metastasis of HER2 Positive Breast Cancer

Who this might be right for
Breast CancerMetastatic Breast Cancer
Fudan University 50
Testing effectiveness (Phase 2)Looking for participantsNCT04348747
What this trial is testing

Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Malignant Neoplasm in the BrainMetastatic Triple-Negative Breast Carcinoma+1 more
Roswell Park Cancer Institute 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT05041842
What this trial is testing

Treatment With Tucatinib in Patients With an Isolated Brain Progression of a Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer With a Isolated Brain Progression
UNICANCER 53
Not applicableUnknownNCT06015100
What this trial is testing

Efficacy and Safety of Inetetamab Plus Pyrotiniband and Capecitabine in HER2-positive Metastatic Breast Cancer Patients With or Without Brain Metastasis

Who this might be right for
Breast Cancer
Yan Xue 40
Testing effectiveness (Phase 2)UnknownNCT04639271
What this trial is testing

Pyrotinib, Trastuzumab And Abraxane in HER2-positive MBC With Brain Metastasis

Who this might be right for
Breast CancerHER2-positive Breast Cancer
Shandong Cancer Hospital and Institute 100
Large-scale testing (Phase 3)Active Not RecruitingNCT04739761
What this trial is testing

T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Who this might be right for
Breast Cancer
AstraZeneca 506
Testing effectiveness (Phase 2)WithdrawnNCT03203616
What this trial is testing

Kadcyla In pAtients With bRAin Metastasis

Who this might be right for
Metastatic HER2-positive Breast Cancer With Brain Metastasis
Jules Bordet Institute
Testing effectiveness (Phase 2)WithdrawnNCT00397501
What this trial is testing

BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerCognitive/Functional Effects+2 more
OHSU Knight Cancer Institute
Not applicableLooking for participantsNCT04030507
What this trial is testing

Screening Magnetic Resonance Imaging of the Brain in Patients With Breast Cancer

Who this might be right for
Breast CancerHER2-positive Breast CancerTriple Negative Breast Cancer+3 more
Dana-Farber Cancer Institute 214
Testing effectiveness (Phase 2)Study completedNCT00098605
What this trial is testing

Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases

Who this might be right for
Central Nervous System MetastasesHER2-positive Breast CancerMale Breast Cancer+3 more
National Cancer Institute (NCI) 37
Testing effectiveness (Phase 2)Ended earlyNCT02154529
What this trial is testing

Study of the Combination of KD019 and Trastuzumab in Subjects With HER2-Positive Metastatic Breast Cancer

Who this might be right for
HER-2 Positive Breast CancerMetastatic Malignant Neoplasm to Brain
Kadmon Corporation, LLC 17
Testing effectiveness (Phase 2)UnknownNCT05018702
What this trial is testing

ARX788 in HER2-positive Breast Cancer Patients With Brain Metastases

Who this might be right for
HER2-positive, Metastatic Breast Cancer
Fudan University 32
Testing effectiveness (Phase 2)Ended earlyNCT01217411
What this trial is testing

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Who this might be right for
Adult Solid NeoplasmExtensive Stage Lung Small Cell CarcinomaHER2/Neu Negative+10 more
National Cancer Institute (NCI) 5
Testing effectiveness (Phase 2)WithdrawnNCT01924351
What this trial is testing

HER2-positive Breast Cancer With Brain Metastasis (GCC 1345)

Who this might be right for
Breast Cancer With Brain Metastasis
University of Maryland, Baltimore
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