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Results for “Metastatic Malignant Neoplasm in the Central Nervous System”

446 trials

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Showing 20 of 446 results

Testing effectiveness (Phase 2)WithdrawnNCT00397501
What this trial is testing

BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerCognitive/Functional Effects+2 more
OHSU Knight Cancer Institute
Not applicableStudy completedNCT01713699
What this trial is testing

Circulating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for Leptomeningeal Metastases

Who this might be right for
Meningeal Carcinomatosis
The Netherlands Cancer Institute 146
Testing effectiveness (Phase 2)Looking for participantsNCT03508752
What this trial is testing

Neurocognitive Decline in Patients With Brain Metastases

Who this might be right for
Brain Metastases
University of Texas Southwestern Medical Center 80
Large-scale testing (Phase 3)Study completedNCT02360215
What this trial is testing

Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases

Who this might be right for
Cognitive ImpairmentMetastatic Malignant Neoplasm in the BrainSolid Neoplasm
NRG Oncology 518
Testing effectiveness (Phase 2)Looking for participantsNCT07227610
What this trial is testing

Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)

Who this might be right for
Brain MetastasesCancer (With CNS Involvement)
Medical University of South Carolina 54
Large-scale testing (Phase 3)Study completedNCT01345019
What this trial is testing

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

Who this might be right for
CancerHematologic MalignanciesMultiple Myeloma+3 more
Amgen 1,718
Testing effectiveness (Phase 2)Study completedNCT02336451
What this trial is testing

A Phase II Study to Evaluate the Efficacy and Safety of Oral Ceritinib in Patients With ALK-positive NSCLC Metastatic to the Brain and/or to Leptomeninges

Who this might be right for
ALK-positive Non-small Cell Lung Cancer
Novartis Pharmaceuticals 156
Testing effectiveness (Phase 2)Study completedNCT01806675
What this trial is testing

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

Who this might be right for
Adult Giant Cell GlioblastomaAdult GlioblastomaAdult Gliosarcoma+41 more
Sanjiv Sam Gambhir 25
Testing effectiveness (Phase 2)Ended earlyNCT00659126
What this trial is testing

Ferumoxytol- and Gadolinium-Labeled MRI in Measuring Tumors Before or After Treatment in Patients With Primary or Metastatic Brain Tumors

Who this might be right for
Metastatic Malignant Neoplasm in the BrainPrimary Brain Neoplasm
OHSU Knight Cancer Institute 40
Not applicableStudy completedNCT04132843
What this trial is testing

Novel MRI Techniques for the Characterization and Treatment Assessment of High Grade Brain Lesions

Who this might be right for
Brain NeoplasmLymphomaMetastatic Malignant Neoplasm in the Brain+1 more
M.D. Anderson Cancer Center 6
Testing effectiveness (Phase 2)Study completedNCT02039947
What this trial is testing

Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the Brain

Who this might be right for
Melanoma and Brain Metastases
Novartis Pharmaceuticals 127
Not applicableStudy completedNCT04763148
What this trial is testing

Tumor Heterogeneity in Diffuse Large B-cell Lymphoma in Relation to CNS Involvement and Cell-free DNA

Who this might be right for
Lymphoma, Large B-Cell, Diffuse
Herlev Hospital 26
Testing effectiveness (Phase 2)UnknownNCT01849484
What this trial is testing

Enhancement of Neurocognitive Functions by Hippocampal Sparing Radiotherapy

Who this might be right for
Radiation of Neurocranial Region
University of Erlangen-Nürnberg Medical School 150
Not applicableLooking for participantsNCT05864794
What this trial is testing

Value of Screening MRI Brain in Stage IV Non-small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer Metastatic
University Medical Center Groningen 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT04074096
What this trial is testing

Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis

Who this might be right for
Malignant MelanomaBRAF V600 MutationBrain Metastases
UNICANCER 10
Testing effectiveness (Phase 2)Ended earlyNCT00437073
What this trial is testing

Brain Metastases In ErbB2-Positive Breast Cancer

Who this might be right for
Neoplasms, Breast
GlaxoSmithKline 22
Not applicableStudy completedNCT00937794
What this trial is testing

Screening Study to Identify Pediatric Patients With Hunter Syndrome Who Demonstrate Evidence of Central Nervous System (CNS) Involvement and Who Are Currently Receiving Treatment With Elaprase®

Who this might be right for
Hunter Syndrome
Shire 33
Testing effectiveness (Phase 2)Looking for participantsNCT05692635
What this trial is testing

Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance

Who this might be right for
Brain MetastasesNonsmall Cell Lung Cancer Stage III
Wake Forest University Health Sciences 60
Testing effectiveness (Phase 2)WithdrawnNCT02724904
What this trial is testing

Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplant (HSCT) For Lymphoma

Who this might be right for
Lymphoma
Massachusetts General Hospital
Testing effectiveness (Phase 2)Study completedNCT00039572
What this trial is testing

Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain

Who this might be right for
Brain and Central Nervous System TumorsMelanoma (Skin)Metastatic Cancer
Beth Israel Deaconess Medical Center
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