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Results for “Metastatic Malignant Neoplasm in the Central Nervous System”

459 trials

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Showing 20 of 459 results

Very early researchUnknownNCT05459441
What this trial is testing

Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases

Who this might be right for
GliomaBrain Metastases
Shanghai Pudong Hospital 30
Not applicableLooking for participantsNCT05746325
What this trial is testing

Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Leptomeninges+2 more
Mayo Clinic 5
Not applicableStudy completedNCT05169203
What this trial is testing

The Use of Biomarkers to Predict CNS Involvement in Diffuse Large B-Cell Lymphoma: a Danish Nationwide Registry Study

Who this might be right for
Diffuse Large B Cell LymphomaDiffuse Large B-Cell Lymphoma Cell of OriginDiffuse Large B-cell Lymphoma Recurrent
Herlev Hospital 2,969
Not applicableLooking for participantsNCT07143045
What this trial is testing

A Prospective Cohort Study of Zorifertinib as a First-line Treatment in Patients With Epidermal Growth Factor Receptor-mutant Advanced Non-small Cell Lung Cancer With Central Nervous System (CNS) Metastases

Who this might be right for
EGFR Mutant Advanced Non-small Cell Lung CancerCentral Nervous System (CNS) Metastases
Alpha Biopharma (Jiangsu) Co., Ltd. 800
Testing effectiveness (Phase 2)Study completedNCT00372775
What this trial is testing

Study Tests The Safety And Effectiveness Of SU011248 In Patients With Non-Small Cell Lung Cancer Having Brain Metastases

Who this might be right for
Non-Small Cell Lung Cancer
Pfizer 66
Not applicableNot Yet RecruitingNCT06852001
What this trial is testing

Efficacy of the RayerKnife X Stereotactic Radiotherapy System in the Treatment of Brain Metastases

Who this might be right for
Brain MetastasisSRS
Tianjin Medical University Cancer Institute and Hospital 34
Early research (Phase 1)Ended earlyNCT05673109
What this trial is testing

AC176 for the Treatment of Metastatic Castration Resistant Prostate Cancer

Who this might be right for
Metastatic Castration Resistant Prostate Cancer
Accutar Biotechnology Inc 8
Early research (Phase 1)Looking for participantsNCT03423628
What this trial is testing

Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Who this might be right for
Recurrent Glioblastoma MultiformePrimary Glioblastoma MultiformeBrain Neoplasms, Malignant+1 more
AstraZeneca 180
Early research (Phase 1)Study completedNCT03807765
What this trial is testing

Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases

Who this might be right for
Metastatic Breast CancerBrain Metastases
H. Lee Moffitt Cancer Center and Research Institute 14
Testing effectiveness (Phase 2)Ended earlyNCT03190967
What this trial is testing

T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery

Who this might be right for
Breast CancerBrain MetastasisBrain Cancer
National Cancer Institute (NCI) 12
Not applicableTemporarily pausedNCT05428852
What this trial is testing

Keto-Brain:Investigating the Use of Ketogenic Diets in Brain Metastases

Who this might be right for
Brain Metastases, Adult
Ohio State University Comprehensive Cancer Center 24
Not applicableLooking for participantsNCT05033691
What this trial is testing

Evaluate the Efficacy of Osimertinib With Early Intervention SRS Treatment Compared to the Continuation of Osimertinib Alone, in Patients With EGFR Mutated NSCLC and Asymptomatic Brain Metastases

Who this might be right for
NSCLCEGFR Gene MutationEGF-R Positive Non-Small Cell Lung Cancer+2 more
Hadassah Medical Organization 162
Testing effectiveness (Phase 2)Study completedNCT01281696
What this trial is testing

Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis

Who this might be right for
Breast NeoplasmsLeptomeningeal MetastasisBrain Metastases
National Taiwan University Hospital 40
Early research (Phase 1)Study completedNCT01259479
What this trial is testing

Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors

Who this might be right for
Solid TumorsBrain TumorsBrain Metastases
National Cancer Institute (NCI) 9
Early research (Phase 1)Ended earlyNCT03332589
What this trial is testing

E6201 Plus Dabrafenib for the Treatment of Metastatic Melanoma Central Nervous System Metastases (CNS)

Who this might be right for
Malignant MelanomaBrain Metastases
Spirita Oncology, LLC 4
Early research (Phase 1)WithdrawnNCT04585724
What this trial is testing

Stereotactic Radiosurgery With Abemaciclib, Ribociclib, or Palbociclib in Treating Patients With Hormone Receptor Positive Breast Cancer With Brain Metastases

Who this might be right for
Anatomic Stage IV Breast Cancer American Joint Committee on Cancer (AJCC) v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain+1 more
Emory University
Large-scale testing (Phase 3)UnknownNCT02972333
What this trial is testing

Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M

Who this might be right for
EGFR-TKI Resistant MutationNonsmall Cell Lung CancerAZD9291+1 more
Shandong Cancer Hospital and Institute 150
Early research (Phase 1)Not Yet RecruitingNCT07619599
What this trial is testing

A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaMetastatic Malignant Neoplasm in the BrainOligoprogressive Lung Non-Small Cell Carcinoma+1 more
City of Hope Medical Center 6
Testing effectiveness (Phase 2)UnknownNCT01410370
What this trial is testing

Continuous Endostar Infusion Combined With Radiotherapy in Patients With Brain Metastases

Who this might be right for
Brain Metastases
Jiangsu Simcere Pharmaceutical Co., Ltd. 80
Large-scale testing (Phase 3)Active Not RecruitingNCT04114981
What this trial is testing

Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease

Who this might be right for
Metastatic Malignant Neoplasm in the Brain
Alliance for Clinical Trials in Oncology 242
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