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Results for “Metastatic Malignant Neoplasm to the Leptomeninges”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07789912
What this trial is testing

BRain-AVOidant Proton Craniospinal Irradiation for Leptomeningeal Metastases From Solid Tumor Malignancies

Who this might be right for
Leptomeningeal MetastasisBreast CancerLung Cancer (NSCLC)
University of Miami 40
Testing effectiveness (Phase 2)Study completedNCT05146219
What this trial is testing

Study of TY-9591 in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation

Who this might be right for
NSCLCEGFR Activating MutationBrain Metastases+1 more
TYK Medicines, Inc 29
Early research (Phase 1)Study completedNCT03101579
What this trial is testing

Intrathecal Pemetrexed for Recurrent Leptomeningeal Metastases From Non-small Cell Lung Cancer

Who this might be right for
Leptomeningeal Metastases
The First Hospital of Jilin University 13
Not applicableLooking for participantsNCT06638294
What this trial is testing

Study in Patients With Breast Cancer Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis of Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 30
Not applicableLooking for participantsNCT06643000
What this trial is testing

Evaluating High-dose Furmonertinib with Bevacizumab and Pemetrexed for EGFRm NSCLC with Leptomeningeal Metastasis

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal MetastasisEGFR Gene Mutation
Henan Cancer Hospital 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04588545
What this trial is testing

Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease

Who this might be right for
HER2-positive Breast CancerLeptomeningeal MetastasisLeptomeningeal Disease
H. Lee Moffitt Cancer Center and Research Institute 33
Testing effectiveness (Phase 2)Study completedNCT02336451
What this trial is testing

A Phase II Study to Evaluate the Efficacy and Safety of Oral Ceritinib in Patients With ALK-positive NSCLC Metastatic to the Brain and/or to Leptomeninges

Who this might be right for
ALK-positive Non-small Cell Lung Cancer
Novartis Pharmaceuticals 156
Not applicableActive Not RecruitingNCT06984523
What this trial is testing

Study of Craniospinal Irradiation With Linac Based Volumetric Modulated Arc Therapy (VMAT) for Patients With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
NYU Langone Health 20
Testing effectiveness (Phase 2)Ended earlyNCT00005812
What this trial is testing

Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma

Who this might be right for
Brain TumorsCentral Nervous System TumorsLeptomeningeal Metastases
Dartmouth-Hitchcock Medical Center 12
Not applicableUnknownNCT03027544
What this trial is testing

Tomotherapy for Refractory Brain Metastases

Who this might be right for
Brain Metastases
Chinese Academy of Medical Sciences 150
Not applicableUnknownNCT06346977
What this trial is testing

Diagnosis of Leptomeningeal Metastasis and the Monitoring of Intrathecal Chemotherapy Efficacy in NSCLC

Who this might be right for
Diagnosis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 60
Large-scale testing (Phase 3)Ended earlyNCT03275402
What this trial is testing

131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastases

Who this might be right for
NeuroblastomaCNS MetastasesLeptomeningeal Metastases
Y-mAbs Therapeutics 52
Not applicableStudy completedNCT07239102
What this trial is testing

Firmonertinib in the Treatment of EGFR(+) NSCLC Patients With Central Nervous System Metastasis

Who this might be right for
EGFR Positive Non-small Cell Lung CancerCentral Nervous System MetastasisLeptomeningeal Metastasis
Beijing Tiantan Hospital 300
Very early researchUnknownNCT05459441
What this trial is testing

Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases

Who this might be right for
GliomaBrain Metastases
Shanghai Pudong Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT06810804
What this trial is testing

A Phase IIa Study to Evaluate NBQ72S

Who this might be right for
Breast Cancer
Nantong Bencao Quadriga Medical Technology Co. Ltd. 10
Not applicableUnknownNCT05305885
What this trial is testing

Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
The First Hospital of Jilin University 100
Early research (Phase 1)Study completedNCT03719768
What this trial is testing

Avelumab With Radiotherapy in Patients With Leptomeningeal Disease

Who this might be right for
Leptomeningeal MetastasesLeptomeningeal Disease
H. Lee Moffitt Cancer Center and Research Institute 16
Early research (Phase 1)Study completedNCT03520504
What this trial is testing

Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07177950
What this trial is testing

A Two-cohort Study of SHR-A1811 in the Treatment of HER2-positive Breast Cancer With Brain Metastases

Who this might be right for
Breast CancerBrain MetastasesLeptomeningeal Metastasis
Peking University Cancer Hospital & Institute 51
Early research (Phase 1)Looking for participantsNCT06431685
What this trial is testing

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

Who this might be right for
NSCLCLow Dose RadiotherapyPD-1 Inhibitor+1 more
Sichuan University 10
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