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Results for “Metastatic Melanoma in the Central Nervous System”

70 trials

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Showing 20 of 70 results

Very early researchStudy completedNCT05704933
What this trial is testing

Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases

Who this might be right for
Metastatic MelanomaMetastasis to Brain
H. Lee Moffitt Cancer Center and Research Institute 1
Early research (Phase 1)Ended earlyNCT05388877
What this trial is testing

E6201 and Dabrafenib for the Treatment of Central Nervous System Metastases From BRAF V600 Mutated Metastatic Melanoma

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Malignant Neoplasm in the BrainMetastatic Malignant Neoplasm in the Central Nervous System+1 more
Mayo Clinic 13
Not applicableStudy completedNCT01624220
What this trial is testing

A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy

Who this might be right for
Spinal Tumor
M.D. Anderson Cancer Center 41
Large-scale testing (Phase 3)Ended earlyNCT04588246
What this trial is testing

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Lung Non-Small Cell CarcinomaMetastatic Lung Small Cell Carcinoma+9 more
NRG Oncology 19
Early research (Phase 1)Ended earlyNCT05831995
What this trial is testing

Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.

Who this might be right for
Advanced Solid TumorRAS MutationRAF Mutation+1 more
ABM Therapeutics Corporation 12
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Early research (Phase 1)Study completedNCT00019019
What this trial is testing

Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerKidney Cancer+6 more
National Institutes of Health Clinical Center (CC) 70
Testing effectiveness (Phase 2)Ended earlyNCT04789668
What this trial is testing

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Hematopoietic and Lymphoid Cell Neoplasm+11 more
M.D. Anderson Cancer Center 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT03175432
What this trial is testing

Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases

Who this might be right for
BRAF V600 Wild TypeClinical Stage IV Cutaneous Melanoma AJCC v8Intracranial Melanoma+4 more
M.D. Anderson Cancer Center 29
Testing effectiveness (Phase 2)Study completedNCT03625141
What this trial is testing

A Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases

Who this might be right for
Metastatic Melanoma
Hoffmann-La Roche 80
Large-scale testing (Phase 3)Study completedNCT00538850
What this trial is testing

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Who this might be right for
Cancer
INSYS Therapeutics Inc 130
Testing effectiveness (Phase 2)Study completedNCT02039947
What this trial is testing

Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the Brain

Who this might be right for
Melanoma and Brain Metastases
Novartis Pharmaceuticals 127
Early research (Phase 1)Study completedNCT00002754
What this trial is testing

Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Melanoma or Brain Tumors

Who this might be right for
Brain and Central Nervous System TumorsMelanoma (Skin)Metastatic Cancer
Duke University 6
Early research (Phase 1)Study completedNCT00527657
What this trial is testing

Temozolomide, Thalidomide, and Lomustine (TTL) in Melanoma Patients

Who this might be right for
Brain NeoplasmsMelanoma
M.D. Anderson Cancer Center 17
Testing effectiveness (Phase 2)Study completedNCT02978404
What this trial is testing

Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases

Who this might be right for
Clear-Cell Metastatic Renal Cell CarcinomaNon Small Cell Lung Cancer MetastaticBrain Metastases, Adult+2 more
Centre hospitalier de l'Université de Montréal (CHUM) 26
Large-scale testing (Phase 3)UnknownNCT02460068
What this trial is testing

Fotemustine(FTM) Vs FTM and Ipilimumab (IPI) or IPI and Nivolumab in Melanoma Brain Metastasis

Who this might be right for
Brain Metastases
Italian Network for Tumor Biotherapy Foundation 168
Testing effectiveness (Phase 2)Study completedNCT02308020
What this trial is testing

Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain

Who this might be right for
Breast CancerNon-small Cell Lung CancerMelanoma+1 more
Eli Lilly and Company 162
Testing effectiveness (Phase 2)Study completedNCT01266967
What this trial is testing

GSK2118436 in BRAF Mutant Metastatic Melanoma to the Brain

Who this might be right for
Melanoma and Brain Metastases
GlaxoSmithKline 172
Testing effectiveness (Phase 2)Study completedNCT00072163
What this trial is testing

Temozolomide and Thalidomide in Treating Patients With Brain Metastases Secondary to Melanoma

Who this might be right for
Recurrent MelanomaStage IV MelanomaTumors Metastatic to Brain
National Cancer Institute (NCI) 50
Testing effectiveness (Phase 2)Ended earlyNCT00068666
What this trial is testing

Temozolomide and Radiation Therapy in Treating Patients With Stage IV Malignant Melanoma With Measurable and Unresectable Cancer of the Central Nervous System

Who this might be right for
Melanoma (Skin)Metastatic Cancer
Alliance for Clinical Trials in Oncology 41
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