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Results for “Metastatic Melanoma in the Central Nervous System”

69 trials

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Showing 20 of 69 results

Testing effectiveness (Phase 2)Study completedNCT02039947
What this trial is testing

Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the Brain

Who this might be right for
Melanoma and Brain Metastases
Novartis Pharmaceuticals 127
Early research (Phase 1)Study completedNCT00019019
What this trial is testing

Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerKidney Cancer+6 more
National Institutes of Health Clinical Center (CC) 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT04074096
What this trial is testing

Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis

Who this might be right for
Malignant MelanomaBRAF V600 MutationBrain Metastases
UNICANCER 10
Testing effectiveness (Phase 2)Study completedNCT00039572
What this trial is testing

Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain

Who this might be right for
Brain and Central Nervous System TumorsMelanoma (Skin)Metastatic Cancer
Beth Israel Deaconess Medical Center
Testing effectiveness (Phase 2)Looking for participantsNCT05026983
What this trial is testing

Binimetinib and Encorafenib for the Treatment of Metastatic Melanoma and Central Nervous System Metastases

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic MelanomaPathologic Stage IV Cutaneous Melanoma AJCC v8
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Study completedNCT00462982
What this trial is testing

Sunitinib in Treating Patients With Brain Metastases Caused by Kidney Cancer or Melanoma

Who this might be right for
Kidney CancerMelanoma (Skin)Metastatic Cancer
Memorial Sloan Kettering Cancer Center 8
Testing effectiveness (Phase 2)Study completedNCT03873818
What this trial is testing

Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Malignant Neoplasm in the BrainMetastatic Melanoma+1 more
M.D. Anderson Cancer Center 24
Not applicableWithdrawnNCT00378781
What this trial is testing

Heparin or M-EDTA in Preventing Catheter-Related Infections and Blockages in Patients at High Risk for a Catheter-Related Infection

Who this might be right for
Cancer
M.D. Anderson Cancer Center
Early research (Phase 1)Study completedNCT02223052
What this trial is testing

Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies

Who this might be right for
Hematological NeoplasmsNon-Hodgkin's LymphomaHodgkin's Lymphoma+17 more
Celgene 89
Testing effectiveness (Phase 2)Study completedNCT02038218
What this trial is testing

Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors

Who this might be right for
Primary Brain TumorsMetastatic Malignant Neoplasm to Brain
DEKK-TEC, Inc. 29
Testing effectiveness (Phase 2)Study completedNCT03898908
What this trial is testing

Encorafenib and Binimetinib Before Local Treatment in Patients With BRAF Mutant Melanoma Metastatic to the Brain

Who this might be right for
Metastatic MelanomaBrain Metastases
Grupo Español Multidisciplinar de Melanoma 48
Early research (Phase 1)Study completedNCT01460134
What this trial is testing

CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic Cancers

Who this might be right for
CD27 Expressing B-cell Malignancies for Example Hodgkin's LymphomaChronic Lymphocytic LeukemiaMantle Cell Lymphoma+7 more
Celldex Therapeutics 90
Testing effectiveness (Phase 2)Study completedNCT01266967
What this trial is testing

GSK2118436 in BRAF Mutant Metastatic Melanoma to the Brain

Who this might be right for
Melanoma and Brain Metastases
GlaxoSmithKline 172
Testing effectiveness (Phase 2)Looking for participantsNCT03563729
What this trial is testing

Melanoma Metastasized to the Brain and Steroids

Who this might be right for
Malignant Melanoma
Inge Marie Svane 80
Testing effectiveness (Phase 2)Ended earlyNCT00068666
What this trial is testing

Temozolomide and Radiation Therapy in Treating Patients With Stage IV Malignant Melanoma With Measurable and Unresectable Cancer of the Central Nervous System

Who this might be right for
Melanoma (Skin)Metastatic Cancer
Alliance for Clinical Trials in Oncology 41
Testing effectiveness (Phase 2)Study completedNCT01037790
What this trial is testing

Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer

Who this might be right for
Adult Solid TumorAdenocarcinoma of the ColonAdenocarcinoma of the Rectum+36 more
Abramson Cancer Center at Penn Medicine 304
Testing effectiveness (Phase 2)Looking for participantsNCT05909618
What this trial is testing

Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases

Who this might be right for
Advanced GlioblastomaMetastatic Melanoma in the Central Nervous SystemMGMT-Unmethylated Glioblastoma
Sheba Medical Center 33
Early research (Phase 1)Study completedNCT04430842
What this trial is testing

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Who this might be right for
AstrocytomaBrain CancerBrain Metastases+20 more
Quadriga Biosciences, Inc. 15
Not applicableStudy completedNCT02527304
What this trial is testing

Adaptive Staged Stereotactic Body Radiation Therapy in Treating Patients With Spinal Metastases That Cannot Be Removed by Surgery

Who this might be right for
MelanomaMetastatic Malignant Neoplasm in the SpineRenal Cell Carcinoma+2 more
Albert Einstein College of Medicine 24
Testing effectiveness (Phase 2)Study completedNCT02115139
What this trial is testing

GEM STUDY: Radiation And Yervoy in Patients With Melanoma and Brain Metastases

Who this might be right for
MelanomaBrain Metastases
Grupo Español Multidisciplinar de Melanoma 58
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