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Results for “Metastatic Squamous Cell Carcinoma”

1,375 trials

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Showing 20 of 1,375 results

Large-scale testing (Phase 3)UnknownNCT03958890
What this trial is testing

A Clinical Trial Comparing HLX10 With Placebo Combined With Chemotherapy (Cisplatin + 5-fu) in the First-line Treatment of Locally Advanced/Metastatic Esophageal Squamous Cell Carcinoma (ESCC)

Who this might be right for
Esophageal Squamous Cell Carcinoma
Shanghai Henlius Biotech 489
Testing effectiveness (Phase 2)Study completedNCT02259582
What this trial is testing

Carboplatin, Pemetrexed Plus Placebo vs Carboplatin, Pemetrexed Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With Non-Squamous Non-Small Cell Lung Cancer

Who this might be right for
Nonsquamous Nonsmall Cell Neoplasm of Lung
OncoMed Pharmaceuticals, Inc. 82
Testing effectiveness (Phase 2)Study completedNCT00084682
What this trial is testing

Depsipeptide in Unresectable Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Stage IV Squamous Cell Carcinoma of the HypopharynxStage IV Squamous Cell Carcinoma of the LarynxStage IV Squamous Cell Carcinoma of the Lip and Oral Cavity+1 more
National Cancer Institute (NCI) 14
Early research (Phase 1)Ended earlyNCT03809624
What this trial is testing

Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer

Who this might be right for
Metastatic Solid TumorsNon-small Cell Lung CancerMelanoma+6 more
Inhibrx Biosciences, Inc 160
Testing effectiveness (Phase 2)UnknownNCT05522894
What this trial is testing

AK104 Alone or in Combination With Chemotherapy in the First-line Treatment of ESCC

Who this might be right for
Unresectable Esophageal Squamous Cell CarcinomaLocally Advanced Esophageal Squamous Cell CarcinomaMetastatic Esophageal Squamous Cell Carcinoma
Chinese Academy of Medical Sciences 80
Testing effectiveness (Phase 2)Study completedNCT04815720
What this trial is testing

Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC)
Vaccinex Inc. 49
Testing effectiveness (Phase 2)Study completedNCT00043823
What this trial is testing

Avastin and Tarceva for Locally Advanced or Metastatic Non-Squamous Non-Small-Cell Lung Cancer

Who this might be right for
Lung Cancer
M.D. Anderson Cancer Center 41
Testing effectiveness (Phase 2)WithdrawnNCT05359692
What this trial is testing

INCAGN01876 in Combination With Immunotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Metastatic Head and Neck Squamous Cell CarcinomaAdvanced MalignanciesRecurrent Head and Neck Squamous Cell Carcinoma
Incyte Biosciences International Sàrl
Not applicableUnknownNCT05821751
What this trial is testing

The Effect of Prebiotic Inulin on Patients Affected by R/M HNSCC Treated With Immune Checkpoint Inhibitors

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Fondazione del Piemonte per l'Oncologia 40
Large-scale testing (Phase 3)Study completedNCT03515837
What this trial is testing

Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)

Who this might be right for
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 492
Testing effectiveness (Phase 2)Active Not RecruitingNCT06041802
What this trial is testing

Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) (Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180)) in Japanese Participants With Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC) or Locally Advanced (LA) Unresectable cSCC (MK-3475A-E39)

Who this might be right for
Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 19
Early research (Phase 1)Study completedNCT05479812
What this trial is testing

Dose Escalation and Expansion Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid Tumors

Who this might be right for
Metastatic Solid TumorAdvanced Solid Tumor
Werewolf Therapeutics, Inc. 156
Testing effectiveness (Phase 2)UnknownNCT05990231
What this trial is testing

Cadonilimab/Anlotinib in Locally Advanced or Relapsed/Metastatic ESCC Patients After Failure of PD-1 Combined With Platinum-containing Chemotherapy

Who this might be right for
Esophageal Squamous Cell Carcinoma
Second Affiliated Hospital, Zhejiang University, School of Medicine 35
Early research (Phase 1)Study completedNCT04196283
What this trial is testing

Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Advanced Solid Tumors Cancer
AbbVie 30
Testing effectiveness (Phase 2)Study completedNCT02830594
What this trial is testing

Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer

Who this might be right for
Gastric AdenocarcinomaGastric Squamous Cell CarcinomaGastroesophageal Junction Adenocarcinoma+3 more
City of Hope Medical Center 14
Testing effectiveness (Phase 2)Ended earlyNCT02068157
What this trial is testing

Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer

Who this might be right for
Recurrent Laryngeal Squamous Cell CarcinomaRecurrent Laryngeal Verrucous CarcinomaRecurrent Lip and Oral Cavity Squamous Cell Carcinoma+4 more
Roswell Park Cancer Institute 3
Testing effectiveness (Phase 2)Looking for participantsNCT07030257
What this trial is testing

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumor MalignanciesColorectal CarcinomaSmall Cell Lung Cancer ( SCLC )+4 more
Tasca Therapeutics 150
Large-scale testing (Phase 3)Active Not RecruitingNCT04534205
What this trial is testing

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

Who this might be right for
Unresectable Head and Neck Squamous Cell CarcinomaMetastatic Head and Neck CancerRecurrent Head and Neck Cancer
BioNTech SE 358
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07815197
What this trial is testing

Sacituzumab Tirumotecan as Second-Line Treatment for Penile Cancer

Who this might be right for
Penile Squamous Cell CarcinomaMetastatic Penile Squamous Cell Carcinoma
Latin American Cooperative Oncology Group 37
Testing effectiveness (Phase 2)Study completedNCT02499120
What this trial is testing

Safety And Efficacy Study Of Palbociclib Plus Cetuximab Versus Cetuximab To Treat Head And Neck Cancer

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Pfizer 125
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